Fcn3 (ficolin 3) - Rat Genome Database

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Gene: Fcn3 (ficolin 3) Heterocephalus glaber
Analyze
Symbol: Fcn3
Name: ficolin 3
RGD ID: 18903511
Description: ENCODES a protein that exhibits antigen binding (ortholog); identical protein binding (ortholog); INVOLVED IN complement activation (ortholog); complement activation, lectin pathway (ortholog); negative regulation of RNA biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); Immunodeficiency due to Ficolin 3 Deficiency (ortholog); FOUND IN serine-type endopeptidase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); Ficolin-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476411,265,505 - 11,269,650 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476411,265,740 - 11,269,588 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Fcn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476411,265,505 - 11,269,650 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476411,265,740 - 11,269,588 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FCN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38127,369,110 - 27,374,824 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl127,369,110 - 27,374,824 (-)EnsemblGRCh38hg38GRCh38
GRCh37127,695,601 - 27,701,315 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,568,188 - 27,573,902 (-)NCBINCBI36Build 36hg18NCBI36
Build 34127,379,744 - 27,385,457NCBI
Celera126,092,884 - 26,098,611 (-)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef125,951,741 - 25,957,459 (-)NCBIHuRef
CHM1_1127,810,336 - 27,816,061 (-)NCBICHM1_1
T2T-CHM13v2.0127,210,348 - 27,216,135 (-)NCBIT2T-CHM13v2.0
Fcna
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,514,677 - 25,525,448 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,514,678 - 25,518,042 (-)EnsemblGRCm39 Ensembl
GRCm38225,624,665 - 25,635,440 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,624,666 - 25,628,030 (-)EnsemblGRCm38mm10GRCm38
MGSCv37225,480,187 - 25,483,494 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36225,446,675 - 25,449,923 (-)NCBIMGSCv36mm8
Celera225,353,030 - 25,356,335 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.58NCBI
Fcn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554526,630,505 - 6,635,235 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554526,630,548 - 6,635,334 (-)NCBIChiLan1.0ChiLan1.0
FCN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21199,473,046 - 199,511,475 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11198,589,723 - 198,615,789 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,620,373 - 26,636,424 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,676,740 - 27,683,889 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,676,866 - 27,683,861 (-)Ensemblpanpan1.1panPan2
FCN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha269,476,250 - 69,480,708 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0273,460,937 - 73,465,399 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1270,286,939 - 70,291,401 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,298,410 - 71,302,868 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0272,294,469 - 72,298,931 (+)NCBIUU_Cfam_GSD_1.0
Fcn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505845,855,319 - 45,861,098 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647411,680,166 - 11,685,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120105,414,626 - 105,420,684 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20105,414,650 - 105,420,558 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603311,038,178 - 11,049,768 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017394   ⟹   ENSHGLP00000017221
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476411,265,505 - 11,269,650 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000017395   ⟹   ENSHGLP00000017222
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476411,265,505 - 11,269,650 (-)Ensembl
RefSeq Acc Id: XM_004850708   ⟹   XP_004850765
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476411,265,740 - 11,269,588 (-)NCBI
RefSeq Acc Id: XM_004850709   ⟹   XP_004850766
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476411,265,740 - 11,269,588 (-)NCBI
RefSeq Acc Id: XM_021263143   ⟹   XP_021118802
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476411,265,740 - 11,269,541 (-)NCBI
RefSeq Acc Id: XM_021263144   ⟹   XP_021118803
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476411,265,740 - 11,269,541 (-)NCBI
RefSeq Acc Id: XM_021263145   ⟹   XP_021118804
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476411,265,740 - 11,269,542 (-)NCBI
RefSeq Acc Id: XM_021263146   ⟹   XP_021118805
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476411,265,913 - 11,269,545 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004850766   ⟸   XM_004850709
- Peptide Label: isoform X6
- UniProtKB: A0A0P6JN51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850765   ⟸   XM_004850708
- Peptide Label: isoform X4
- UniProtKB: G5AUT5 (UniProtKB/TrEMBL),   A0A0P6JN51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118804   ⟸   XM_021263145
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JN51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118803   ⟸   XM_021263144
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JN51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118802   ⟸   XM_021263143
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JN51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118805   ⟸   XM_021263146
- Peptide Label: isoform X5
RefSeq Acc Id: ENSHGLP00000017221   ⟸   ENSHGLT00000017394
RefSeq Acc Id: ENSHGLP00000017222   ⟸   ENSHGLT00000017395


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012337 Ensembl, ENTREZGENE
  ENSHGLG00100016721 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017394 ENTREZGENE
  ENSHGLT00000017395 ENTREZGENE
  ENSHGLT00100022976 UniProtKB/TrEMBL
Gene3D-CATH 3.90.215.10 UniProtKB/TrEMBL
  Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 UniProtKB/TrEMBL
InterPro Fibrinogen-like_C UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_1 UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/TrEMBL
  Fibrinogen_CS UniProtKB/TrEMBL
KEGG Report hgl:101698364 UniProtKB/TrEMBL
NCBI Gene Fcn3 ENTREZGENE
PANTHER FIBRINOGEN/TENASCIN/ANGIOPOEITIN UniProtKB/TrEMBL
  FICOLIN-3 UniProtKB/TrEMBL
Pfam Fibrinogen_C UniProtKB/TrEMBL
PROSITE FIBRINOGEN_C_1 UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/TrEMBL
SMART FBG UniProtKB/TrEMBL
Superfamily-SCOP SSF56496 UniProtKB/TrEMBL
UniProt A0A0P6JN51 ENTREZGENE, UniProtKB/TrEMBL
  G5AUT5 ENTREZGENE, UniProtKB/TrEMBL