Abca12 (ATP binding cassette subfamily A member 12) - Rat Genome Database

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Gene: Abca12 (ATP binding cassette subfamily A member 12) Heterocephalus glaber
Analyze
Symbol: Abca12
Name: ATP binding cassette subfamily A member 12
RGD ID: 18903347
Description: ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN ceramide metabolic process (ortholog); ceramide transport (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis (ortholog); autosomal recessive congenital ichthyosis 1 (ortholog); autosomal recessive congenital ichthyosis 4A (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); epidermal lamellar body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family A member 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247651,010,287 - 1,197,910 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247651,009,883 - 1,198,225 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Abca12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247651,010,287 - 1,197,910 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247651,009,883 - 1,198,225 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ABCA12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382214,931,542 - 215,138,626 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2214,931,542 - 215,138,626 (-)EnsemblGRCh38hg38GRCh38
GRCh372215,796,266 - 216,003,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362215,504,511 - 215,711,396 (-)NCBINCBI36Build 36hg18NCBI36
Build 342215,621,772 - 215,828,657NCBI
Celera2209,565,986 - 209,772,883 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2207,652,444 - 207,860,132 (-)NCBIHuRef
CHM1_12215,801,932 - 216,008,974 (-)NCBICHM1_1
T2T-CHM13v2.02215,416,237 - 215,623,360 (-)NCBIT2T-CHM13v2.0
Abca12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39171,282,249 - 71,454,069 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl171,281,435 - 71,454,069 (-)EnsemblGRCm39 Ensembl
GRCm38171,243,090 - 71,414,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl171,242,276 - 71,414,910 (-)EnsemblGRCm38mm10GRCm38
MGSCv37171,289,664 - 71,461,484 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36171,176,298 - 71,348,118 (-)NCBIMGSCv36mm8
Celera171,798,849 - 71,970,916 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map135.81NCBI
Abca12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8980,272,121 - 80,445,340 (-)NCBIGRCr8
mRatBN7.2972,822,661 - 72,995,748 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl972,823,350 - 72,996,049 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0978,521,477 - 78,693,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl978,522,464 - 78,693,028 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0978,296,546 - 78,466,160 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4970,328,327 - 70,501,128 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1970,475,308 - 70,648,110 (-)NCBI
Celera970,239,719 - 70,413,488 (-)NCBICelera
Cytogenetic Map9q33NCBI
Abca12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955457879,510 - 1,062,713 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955457885,941 - 1,062,713 (+)NCBIChiLan1.0ChiLan1.0
ABCA12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213117,561,295 - 117,675,718 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B117,576,162 - 117,783,122 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B102,194,286 - 102,401,175 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B220,668,359 - 220,873,566 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B220,668,957 - 220,873,566 (-)Ensemblpanpan1.1panPan2
ABCA12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13722,136,732 - 22,306,917 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3722,138,245 - 22,405,736 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3722,965,092 - 23,134,494 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03722,160,884 - 22,330,640 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3722,161,609 - 22,374,148 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13722,049,739 - 22,219,457 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03722,001,062 - 22,170,768 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03722,017,286 - 22,187,312 (-)NCBIUU_Cfam_GSD_1.0
Abca12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303170,531,373 - 170,687,485 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365861,938,617 - 2,094,279 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365861,938,617 - 2,094,231 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCA12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15117,244,719 - 117,450,863 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115117,244,704 - 117,451,009 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215129,788,302 - 129,879,763 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABCA12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110100,759,196 - 100,972,307 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10100,759,225 - 100,888,912 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604098,407,554 - 98,614,915 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000006593   ⟹   ENSHGLP00000006511
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247651,010,287 - 1,197,910 (+)Ensembl
RefSeq Acc Id: XM_021263432   ⟹   XP_021119091
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247651,009,883 - 1,198,225 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021119091 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006511
Reference Protein Sequences
RefSeq Acc Id: XP_021119091   ⟸   XM_021263432
- UniProtKB: G5BHR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000006511   ⟸   ENSHGLT00000006593


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004765 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006593 ENTREZGENE
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC2_TM UniProtKB/TrEMBL
  ABC_transporter-like_ATP-bd UniProtKB/TrEMBL
  ABC_transporter-like_CS UniProtKB/TrEMBL
  ABCA UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Abca12 ENTREZGENE
PANTHER ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA UniProtKB/TrEMBL
  GLUCOSYLCERAMIDE TRANSPORTER ABCA12 UniProtKB/TrEMBL
Pfam ABC2_membrane_3 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt G5BHR7 ENTREZGENE, UniProtKB/TrEMBL