Atp1b1 (ATPase Na+/K+ transporting subunit beta 1) - Rat Genome Database

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Gene: Atp1b1 (ATPase Na+/K+ transporting subunit beta 1) Heterocephalus glaber
Analyze
Symbol: Atp1b1
Name: ATPase Na+/K+ transporting subunit beta 1
RGD ID: 18903282
Description: ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); P-type sodium:potassium-exchanging transporter activity (ortholog); INVOLVED IN ATP metabolic process (ortholog); blastocyst development (ortholog); cardiac muscle contraction (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); acute myeloid leukemia (ortholog); Cardiac Arrhythmias (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/potassium-transporting ATPase subunit beta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248267,054,371 - 7,076,919 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248267,058,046 - 7,076,919 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Atp1b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248267,054,371 - 7,076,919 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248267,058,046 - 7,076,919 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ATP1B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,106,690 - 169,132,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,105,697 - 169,310,992 (+)EnsemblGRCh38hg38GRCh38
GRCh371169,075,928 - 169,101,957 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,342,571 - 167,368,584 (+)NCBINCBI36Build 36hg18NCBI36
Build 341165,807,604 - 165,833,618NCBI
Celera1142,186,000 - 142,212,016 (+)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1140,321,997 - 140,348,078 (+)NCBIHuRef
CHM1_11170,498,009 - 170,524,021 (+)NCBICHM1_1
T2T-CHM13v2.01168,462,171 - 168,488,201 (+)NCBIT2T-CHM13v2.0
Atp1b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,264,668 - 164,285,924 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,264,678 - 164,285,924 (-)EnsemblGRCm39 Ensembl
GRCm381164,437,099 - 164,458,355 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,437,109 - 164,458,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv371166,367,398 - 166,388,486 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361166,273,942 - 166,295,030 (-)NCBIMGSCv36mm8
Celera1166,878,624 - 166,899,734 (-)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.75NCBI
Atp1b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81379,319,708 - 79,340,226 (-)NCBIGRCr8
mRatBN7.21376,786,580 - 76,807,096 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1376,786,578 - 76,807,459 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1379,404,955 - 79,425,485 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01380,708,953 - 80,729,485 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01377,964,000 - 77,984,560 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01382,737,161 - 82,757,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,737,159 - 82,758,004 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01387,621,447 - 87,641,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41380,214,056 - 80,234,576 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11380,228,241 - 80,249,087 (-)NCBI
Celera1376,517,954 - 76,538,475 (-)NCBICelera
RH 3.4 Map13485.8RGD
Cytogenetic Map13q23NCBI
Atp1b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554628,073,679 - 8,094,880 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554628,072,519 - 8,095,311 (-)NCBIChiLan1.0ChiLan1.0
ATP1B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2180,630,907 - 80,659,587 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1180,299,320 - 80,328,363 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,592,667 - 144,621,052 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11148,314,700 - 148,343,205 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1148,314,793 - 148,342,050 (+)Ensemblpanpan1.1panPan2
ATP1B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1729,464,132 - 29,487,124 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl729,464,132 - 29,487,947 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha728,995,904 - 29,019,080 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0729,266,289 - 29,289,513 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl729,265,440 - 29,289,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1729,114,027 - 29,137,166 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0729,155,842 - 29,179,013 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0729,386,814 - 29,410,001 (-)NCBIUU_Cfam_GSD_1.0
Atp1b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934499,591,400 - 99,613,578 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648117,436,270 - 17,460,348 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648117,438,146 - 17,460,329 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP1B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl481,911,561 - 81,991,840 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1481,912,543 - 81,937,015 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2489,530,583 - 89,550,423 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap4q1.3-q2.1NCBI
ATP1B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12559,898,745 - 59,925,166 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2559,895,341 - 59,925,522 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605561,575,309 - 61,602,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021244711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01082602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000002698   ⟹   ENSHGLP00000002645
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248267,054,371 - 7,076,919 (+)Ensembl
RefSeq Acc Id: XM_021244711   ⟹   XP_021100370
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248267,058,046 - 7,076,919 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021100370 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021100370   ⟸   XM_021244711
Ensembl Acc Id: ENSHGLP00000002645   ⟸   ENSHGLT00000002698


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001991 Ensembl
NCBI Gene Atp1b1 ENTREZGENE
UniProt A0AAX6RW87_HETGA UniProtKB/TrEMBL