Rgl1 (ral guanine nucleotide dissociation stimulator like 1) - Rat Genome Database

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Gene: Rgl1 (ral guanine nucleotide dissociation stimulator like 1) Heterocephalus glaber
Analyze
Symbol: Rgl1
Name: ral guanine nucleotide dissociation stimulator like 1
RGD ID: 18903151
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN Ras protein signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ral guanine nucleotide dissociation stimulator-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,950,327 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248149,747,154 - 10,062,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,950,327 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248149,747,154 - 10,062,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381183,636,109 - 183,928,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1183,636,085 - 183,928,532 (+)EnsemblGRCh38hg38GRCh38
GRCh371183,605,244 - 183,897,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,871,831 - 182,164,289 (+)NCBINCBI36Build 36hg18NCBI36
Build 341180,336,876 - 180,629,322NCBI
Celera1156,716,240 - 157,008,586 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1154,841,067 - 155,133,408 (+)NCBIHuRef
CHM1_11185,027,897 - 185,320,329 (+)NCBICHM1_1
T2T-CHM13v2.01182,995,391 - 183,287,882 (+)NCBIT2T-CHM13v2.0
Rgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,392,513 - 152,642,056 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,392,511 - 152,642,102 (-)EnsemblGRCm39 Ensembl
GRCm381152,516,762 - 152,766,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,516,760 - 152,766,351 (-)EnsemblGRCm38mm10GRCm38
MGSCv371154,364,660 - 154,472,241 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,279,748 - 154,387,329 (-)NCBIMGSCv36mm8
Celera1154,937,769 - 155,046,515 (-)NCBICelera
Cytogenetic Map1G2- G3NCBI
cM Map164.85NCBI
Ralgdsl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81367,184,402 - 67,454,019 (-)NCBIGRCr8
mRatBN7.21364,634,489 - 64,904,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,635,246 - 64,904,191 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1367,243,711 - 67,506,393 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,520,706 - 68,799,251 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01365,781,720 - 66,050,138 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01369,909,122 - 70,174,590 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1369,909,096 - 70,174,565 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01374,881,101 - 75,145,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41367,468,218 - 67,754,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11367,483,775 - 67,596,194 (-)NCBI
Celera1364,547,086 - 64,810,801 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540622,483,336 - 22,670,537 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540622,419,137 - 22,670,537 (+)NCBIChiLan1.0ChiLan1.0
RGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2165,790,123 - 66,081,962 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,473,320 - 65,765,120 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01159,166,090 - 159,457,883 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,323,651 - 163,614,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,429,258 - 163,614,657 (+)Ensemblpanpan1.1panPan2
RGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,986,304 - 17,236,549 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl717,041,296 - 17,235,193 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha716,571,833 - 16,821,876 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0716,718,212 - 16,968,704 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl716,718,185 - 16,968,890 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1716,626,490 - 16,876,720 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0716,735,857 - 16,985,375 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0716,866,935 - 17,116,349 (+)NCBIUU_Cfam_GSD_1.0
Rgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934488,179,408 - 88,420,192 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,267,012 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364816,026,157 - 6,175,453 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,848,338 - 125,144,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19124,848,358 - 125,143,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29137,178,640 - 137,472,441 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12545,444,588 - 45,730,912 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2545,444,468 - 45,568,506 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605546,660,856 - 46,947,508 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004862803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004862804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004862805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013078924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021242892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01077816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01077834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000026805   ⟹   ENSHGLP00000026569
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,950,327 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000026806   ⟹   ENSHGLP00000026570
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,921,851 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000026807   ⟹   ENSHGLP00000026571
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,871,726 (-)Ensembl
RefSeq Acc Id: XM_004862803   ⟹   XP_004862860
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248149,747,154 - 10,062,828 (-)NCBI
RefSeq Acc Id: XM_004862804   ⟹   XP_004862861
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248149,747,154 - 9,871,122 (-)NCBI
RefSeq Acc Id: XM_004862805   ⟹   XP_004862862
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248149,747,154 - 10,062,827 (-)NCBI
RefSeq Acc Id: XM_013078924   ⟹   XP_012934378
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248149,747,154 - 9,972,951 (-)NCBI
RefSeq Acc Id: XM_021242892   ⟹   XP_021098551
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248149,747,154 - 9,950,276 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004862860   ⟸   XM_004862803
- Peptide Label: isoform X1
- UniProtKB: G5BGP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862862   ⟸   XM_004862805
- Peptide Label: isoform X3
- UniProtKB: G5BGP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012934378   ⟸   XM_013078924
- Peptide Label: isoform X1
- UniProtKB: G5BGP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098551   ⟸   XM_021242892
- Peptide Label: isoform X1
- UniProtKB: G5BGP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862861   ⟸   XM_004862804
- Peptide Label: isoform X2
- UniProtKB: G5BGP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000026569   ⟸   ENSHGLT00000026805
RefSeq Acc Id: ENSHGLP00000026570   ⟸   ENSHGLT00000026806
RefSeq Acc Id: ENSHGLP00000026571   ⟸   ENSHGLT00000026807


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018901 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026805 ENTREZGENE
  ENSHGLT00000026806 ENTREZGENE
  ENSHGLT00000026807 ENTREZGENE
Gene3D-CATH Ras guanine-nucleotide exchange factors catalytic domain UniProtKB/TrEMBL
  Son of sevenless (SoS) protein Chain: S domain 1 UniProtKB/TrEMBL
InterPro RA_dom UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras-like_Gua-exchang_fac_N UniProtKB/TrEMBL
  Ras_G-nucl-exch_fac_CS UniProtKB/TrEMBL
  Ras_GEF_dom_sf UniProtKB/TrEMBL
  RASGEF_cat_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
  RGL1_RA UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Rgl1 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE EXCHANGE FACTOR UniProtKB/TrEMBL
  RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1 UniProtKB/TrEMBL
Pfam PF00788 UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
  RasGEF_N UniProtKB/TrEMBL
PROSITE PS50200 UniProtKB/TrEMBL
  RASGEF UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
  RASGEF_NTER UniProtKB/TrEMBL
SMART RasGEF UniProtKB/TrEMBL
  RasGEFN UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP Ras GEF UniProtKB/TrEMBL
  Ubiquitin-like UniProtKB/TrEMBL
UniProt G5BGP4 ENTREZGENE, UniProtKB/TrEMBL