Phc3 (polyhomeotic homolog 3) - Rat Genome Database

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Gene: Phc3 (polyhomeotic homolog 3) Heterocephalus glaber
Analyze
Symbol: Phc3
Name: polyhomeotic homolog 3
RGD ID: 18903150
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); histone binding (inferred); INVOLVED IN negative regulation of DNA-templated transcription (inferred); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 1 (ortholog); Fanconi syndrome (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (ortholog); PcG protein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Polyhomeotic-like protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473048,153,414 - 48,238,279 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473048,144,767 - 48,258,807 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Phc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473048,153,414 - 48,238,279 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473048,144,767 - 48,258,807 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PHC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383170,087,584 - 170,181,733 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3170,086,732 - 170,181,749 (-)EnsemblGRCh38hg38GRCh38
GRCh373169,805,372 - 169,899,521 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363171,288,062 - 171,382,231 (-)NCBINCBI36Build 36hg18NCBI36
Build 343171,297,359 - 171,382,218NCBI
Celera3168,204,684 - 168,298,819 (-)NCBICelera
Cytogenetic Map3q26.2NCBI
HuRef3167,175,971 - 167,270,090 (-)NCBIHuRef
CHM1_13169,768,808 - 169,862,971 (-)NCBICHM1_1
T2T-CHM13v2.03172,872,255 - 172,966,417 (-)NCBIT2T-CHM13v2.0
Phc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39330,953,444 - 31,023,628 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl330,953,520 - 31,023,564 (-)EnsemblGRCm39 Ensembl
GRCm38330,899,295 - 30,969,479 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl330,899,371 - 30,969,415 (-)EnsemblGRCm38mm10GRCm38
MGSCv37330,798,217 - 30,868,337 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36331,097,687 - 31,160,279 (-)NCBIMGSCv36mm8
Celera330,811,260 - 30,881,515 (-)NCBICelera
Cytogenetic Map3A3NCBI
cM Map314.36NCBI
Phc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82114,337,180 - 114,412,132 (+)NCBIGRCr8
mRatBN7.22112,408,709 - 112,483,719 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2112,408,531 - 112,476,540 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2119,066,709 - 119,130,894 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02117,179,274 - 117,243,458 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02111,882,251 - 111,946,375 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02116,028,735 - 116,103,227 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2116,028,781 - 116,096,045 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02135,723,966 - 135,798,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42116,831,190 - 116,895,396 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12116,772,507 - 116,840,332 (+)NCBI
Celera2107,599,159 - 107,663,187 (+)NCBICelera
Cytogenetic Map2q24NCBI
Phc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955420329,215 - 403,168 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955420329,215 - 403,191 (-)NCBIChiLan1.0ChiLan1.0
PHC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22167,980,926 - 168,075,166 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13167,985,650 - 168,079,877 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03167,100,797 - 167,194,987 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13175,291,594 - 175,384,905 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3175,291,594 - 175,384,905 (-)Ensemblpanpan1.1panPan2
PHC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13434,651,828 - 34,739,613 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3434,668,040 - 34,739,882 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3443,665,363 - 43,752,722 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03434,733,032 - 34,820,084 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3434,744,357 - 34,820,676 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13434,678,961 - 34,765,867 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03434,646,521 - 34,733,841 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03434,910,864 - 34,997,759 (-)NCBIUU_Cfam_GSD_1.0
Phc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602101,283,888 - 101,358,093 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365932,263,829 - 2,336,856 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365932,263,892 - 2,336,856 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13108,776,220 - 108,883,572 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113108,791,675 - 108,883,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213117,553,499 - 117,628,878 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11519,214,818 - 19,308,248 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1519,217,677 - 19,293,583 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606328,013,543 - 28,108,102 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020829   ⟹   ENSHGLP00000020627
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473048,153,414 - 48,238,279 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000020830   ⟹   ENSHGLP00000020628
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473048,153,414 - 48,235,357 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000020831   ⟹   ENSHGLP00000020629
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473048,153,659 - 48,237,745 (-)Ensembl
RefSeq Acc Id: XM_004834579   ⟹   XP_004834636
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,238,318 (-)NCBI
RefSeq Acc Id: XM_004834580   ⟹   XP_004834637
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,238,318 (-)NCBI
RefSeq Acc Id: XM_013071518   ⟹   XP_012926972
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,238,318 (-)NCBI
RefSeq Acc Id: XM_013071523   ⟹   XP_012926977
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,238,318 (-)NCBI
RefSeq Acc Id: XM_013071526   ⟹   XP_012926980
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,238,318 (-)NCBI
RefSeq Acc Id: XM_021254029   ⟹   XP_021109688
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,237,739 (-)NCBI
RefSeq Acc Id: XM_021254030   ⟹   XP_021109689
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,258,807 (-)NCBI
RefSeq Acc Id: XM_021254033   ⟹   XP_021109692
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,239,103 (-)NCBI
RefSeq Acc Id: XR_002393038
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473048,144,767 - 48,238,318 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021109689   ⟸   XM_021254030
- Peptide Label: isoform X2
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109692   ⟸   XM_021254033
- Peptide Label: isoform X2
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926980   ⟸   XM_013071526
- Peptide Label: isoform X6
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834637   ⟸   XM_004834580
- Peptide Label: isoform X5
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926977   ⟸   XM_013071523
- Peptide Label: isoform X4
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834636   ⟸   XM_004834579
- Peptide Label: isoform X3
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926972   ⟸   XM_013071518
- Peptide Label: isoform X1
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109688   ⟸   XM_021254029
- Peptide Label: isoform X2
- UniProtKB: G5AXZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020627   ⟸   ENSHGLT00000020829
RefSeq Acc Id: ENSHGLP00000020629   ⟸   ENSHGLT00000020831
RefSeq Acc Id: ENSHGLP00000020628   ⟸   ENSHGLT00000020830


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014756 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020829 ENTREZGENE
  ENSHGLT00000020830 ENTREZGENE
  ENSHGLT00000020831 ENTREZGENE
Gene3D-CATH 3.30.60.160 UniProtKB/TrEMBL
  Transcription Factor, Ets-1 UniProtKB/TrEMBL
InterPro SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Znf_FCS UniProtKB/TrEMBL
  Znf_FCS_sf UniProtKB/TrEMBL
NCBI Gene Phc3 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/TrEMBL
  POLYHOMEOTIC-LIKE PROTEIN 3 UniProtKB/TrEMBL
Pfam SAM_1 UniProtKB/TrEMBL
  zf-FCS_1 UniProtKB/TrEMBL
PROSITE SAM_DOMAIN UniProtKB/TrEMBL
  ZF_FCS UniProtKB/TrEMBL
SMART SAM UniProtKB/TrEMBL
Superfamily-SCOP SAM/Pointed domain UniProtKB/TrEMBL
UniProt G5AXZ5 ENTREZGENE, UniProtKB/TrEMBL