Prxl2c (peroxiredoxin like 2C) - Rat Genome Database

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Gene: Prxl2c (peroxiredoxin like 2C) Heterocephalus glaber
Analyze
Symbol: Prxl2c
Name: peroxiredoxin like 2C
RGD ID: 18903004
Description: INVOLVED IN positive regulation of ERK1 and ERK2 cascade (ortholog); positive regulation of glycolytic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Aaed1; AhpC/TSA antioxidant enzyme domain containing 1; thioredoxin-like protein AAED1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475317,901,544 - 17,918,042 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475317,901,281 - 17,922,146 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Prxl2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475317,901,544 - 17,918,042 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475317,901,281 - 17,922,146 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRXL2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38996,639,577 - 96,655,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl996,639,577 - 96,655,317 (-)EnsemblGRCh38hg38GRCh38
GRCh37999,401,859 - 99,417,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,443,354 - 98,457,420 (-)NCBINCBI36Build 36hg18NCBI36
Celera969,845,106 - 69,859,172 (-)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef969,014,734 - 69,028,253 (-)NCBIHuRef
CHM1_1999,550,355 - 99,564,421 (-)NCBICHM1_1
T2T-CHM13v2.09108,811,352 - 108,827,123 (-)NCBIT2T-CHM13v2.0
Prxl2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,437,612 - 64,460,524 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,423,094 - 64,460,524 (-)EnsemblGRCm39 Ensembl
GRCm381364,289,798 - 64,312,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,275,280 - 64,312,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv371364,393,144 - 64,414,018 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361364,301,606 - 64,326,737 (-)NCBIMGSCv36mm8
Celera1365,956,327 - 65,976,100 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
Prxl2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817817,932 - 849,965 (+)NCBIGRCr8
mRatBN7.217812,199 - 839,536 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17812,213 - 844,075 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx17830,906 - 848,128 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,373,483 - 2,390,705 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017828,334 - 845,556 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,798,224 - 1,830,011 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,798,388 - 1,830,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,787,497 - 1,819,908 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,336,052 - 6,370,548 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera171,672,532 - 1,704,457 (-)NCBICelera
Cytogenetic Map17p14NCBI
PRXL2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21142,796,286 - 42,810,351 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1942,798,683 - 42,812,729 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0967,737,639 - 67,751,691 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1995,857,770 - 95,889,532 (-)NCBIpanpan1.1PanPan1.1panPan2
PRXL2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,199,278 - 70,209,026 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,199,357 - 70,208,534 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha170,962,502 - 70,972,184 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0170,487,981 - 70,508,109 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl170,498,486 - 70,509,863 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1170,312,093 - 70,321,759 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0170,074,911 - 70,084,654 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0170,786,250 - 70,795,855 (+)NCBIUU_Cfam_GSD_1.0
PRXL2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1025,428,164 - 25,446,185 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11025,428,129 - 25,444,609 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21076,570,687 - 76,584,991 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRXL2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112106,486,772 - 106,500,124 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12106,486,811 - 106,499,618 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603894,883,326 - 94,897,531 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023436   ⟹   ENSHGLP00000023220
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475317,901,544 - 17,918,042 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000023437   ⟹   ENSHGLP00000023221
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475317,901,544 - 17,917,902 (+)Ensembl
RefSeq Acc Id: XM_004846087   ⟹   XP_004846144
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475317,901,458 - 17,918,042 (+)NCBI
RefSeq Acc Id: XM_021259387   ⟹   XP_021115046
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475317,901,302 - 17,922,146 (+)NCBI
RefSeq Acc Id: XM_021259388   ⟹   XP_021115047
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475317,901,281 - 17,913,621 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846144 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115046 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115047 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09649 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023220
Reference Protein Sequences
RefSeq Acc Id: XP_021115047   ⟸   XM_021259388
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021115046   ⟸   XM_021259387
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004846144   ⟸   XM_004846087
- Peptide Label: isoform X1
- UniProtKB: G5BK38 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000023220   ⟸   ENSHGLT00000023436
RefSeq Acc Id: ENSHGLP00000023221   ⟸   ENSHGLT00000023437


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016555 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023436 ENTREZGENE
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro PXL2A/B/C UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene Prxl2c ENTREZGENE
PANTHER PEROXIREDOXIN-LIKE 2C UniProtKB/TrEMBL
  PTHR28630 UniProtKB/TrEMBL
Pfam AhpC-TSA_2 UniProtKB/TrEMBL
Superfamily-SCOP Thioredoxin-like UniProtKB/TrEMBL
UniProt G5BK38 ENTREZGENE, UniProtKB/TrEMBL