Scai (suppressor of cancer cell invasion) - Rat Genome Database

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Gene: Scai (suppressor of cancer cell invasion) Heterocephalus glaber
Analyze
Symbol: Scai
Name: suppressor of cancer cell invasion
RGD ID: 18902423
Description: ENCODES a protein that exhibits transcription corepressor activity (inferred); INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of Rho protein signal transduction (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nuclear membrane (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein SCAI
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476010,076,998 - 10,246,535 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476010,076,870 - 10,248,480 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Scai
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476010,076,998 - 10,246,535 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476010,076,870 - 10,248,480 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SCAI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389124,942,608 - 125,143,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9124,942,608 - 125,143,528 (-)EnsemblGRCh38hg38GRCh38
GRCh379127,704,887 - 127,905,807 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,754,888 - 126,945,596 (-)NCBINCBI36Build 36hg18NCBI36
Build 349124,794,620 - 124,985,329NCBI
Celera998,352,855 - 98,553,772 (-)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef997,317,193 - 97,517,971 (-)NCBIHuRef
CHM1_19127,853,646 - 128,054,558 (-)NCBICHM1_1
T2T-CHM13v2.09137,140,969 - 137,341,870 (-)NCBIT2T-CHM13v2.0
Scai
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,956,226 - 39,080,770 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl238,956,226 - 39,080,746 (-)EnsemblGRCm39 Ensembl
GRCm38239,066,214 - 39,190,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl239,066,214 - 39,190,734 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,921,734 - 39,046,250 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36238,888,223 - 39,012,739 (-)NCBIMGSCv36mm8
Celera240,791,951 - 40,916,923 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.42NCBI
Scai
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8343,222,983 - 43,335,056 (-)NCBIGRCr8
mRatBN7.2322,813,283 - 22,925,337 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl322,819,574 - 22,925,363 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx326,281,839 - 26,393,797 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0334,866,820 - 34,978,786 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0332,679,424 - 32,791,572 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0323,357,586 - 23,474,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,582,235 - 28,696,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,856,362 - 18,960,182 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera321,249,476 - 21,357,620 (-)NCBICelera
Cytogenetic Map3q12NCBI
Scai
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554193,137,749 - 3,296,454 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554193,137,745 - 3,296,460 (+)NCBIChiLan1.0ChiLan1.0
SCAI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21114,214,418 - 14,415,795 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1914,216,784 - 14,418,139 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0996,063,149 - 96,264,502 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19124,579,449 - 124,780,072 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9124,589,616 - 124,780,072 (-)Ensemblpanpan1.1panPan2
SCAI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1957,924,995 - 58,090,837 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl957,924,530 - 58,082,053 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha957,124,828 - 57,289,680 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0958,845,385 - 59,011,277 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl958,845,415 - 59,003,189 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1957,604,632 - 57,770,289 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0957,921,148 - 58,086,095 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0958,011,467 - 58,176,812 (+)NCBIUU_Cfam_GSD_1.0
Scai
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947193,376,918 - 193,508,070 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648713,146,123 - 13,276,617 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648713,145,445 - 13,276,539 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCAI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,714,211 - 265,867,101 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,710,644 - 265,867,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,541,771 - 299,618,963 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCAI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11213,010,370 - 13,194,231 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1213,010,479 - 13,192,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660792,908,330 - 3,093,627 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000016497   ⟹   ENSHGLP00000016328
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476010,076,998 - 10,246,535 (+)Ensembl
RefSeq Acc Id: XM_004849384   ⟹   XP_004849441
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476010,076,870 - 10,248,480 (+)NCBI
RefSeq Acc Id: XM_021262077   ⟹   XP_021117736
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476010,076,870 - 10,248,480 (+)NCBI
RefSeq Acc Id: XR_002396582
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476010,076,870 - 10,239,619 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004849441 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117736 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016328
Reference Protein Sequences
RefSeq Acc Id: XP_004849441   ⟸   XM_004849384
- Peptide Label: isoform X1
- UniProtKB: G5B6W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117736   ⟸   XM_021262077
- Peptide Label: isoform X2
- UniProtKB: G5B6W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000016328   ⟸   ENSHGLT00000016497


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011703 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000016497 ENTREZGENE
InterPro SCAI UniProtKB/TrEMBL
NCBI Gene Scai ENTREZGENE
PANTHER PROTEIN SCAI UniProtKB/TrEMBL
  PROTEIN SCAI UniProtKB/TrEMBL
Pfam SCAI UniProtKB/TrEMBL
UniProt G5B6W0 ENTREZGENE, UniProtKB/TrEMBL