Slc24a4 (solute carrier family 24 member 4) - Rat Genome Database

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Gene: Slc24a4 (solute carrier family 24 member 4) Heterocephalus glaber
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Symbol: Slc24a4
Name: solute carrier family 24 member 4
RGD ID: 18902186
Description: ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); calmodulin binding (ortholog); INVOLVED IN amelogenesis (ortholog); calcium ion export across plasma membrane (ortholog); calcium ion homeostasis (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH achondrogenesis type IA (ortholog); amelogenesis imperfecta (ortholog); amelogenesis imperfecta hypomaturation type 2A5 (ortholog); FOUND IN apical plasma membrane (ortholog); cone photoreceptor outer segment (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sodium/potassium/calcium exchanger 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247348,911,455 - 9,063,063 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247348,911,376 - 9,069,054 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc24a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247348,911,455 - 9,063,063 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247348,911,376 - 9,069,054 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLC24A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,322,581 - 92,501,481 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1492,322,581 - 92,501,481 (+)EnsemblGRCh38hg38GRCh38
GRCh371492,788,925 - 92,967,825 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361491,858,678 - 92,032,349 (+)NCBINCBI36Build 36hg18NCBI36
Celera1472,841,198 - 73,019,912 (+)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1472,971,235 - 73,150,009 (+)NCBIHuRef
CHM1_11492,727,545 - 92,906,261 (+)NCBICHM1_1
T2T-CHM13v2.01486,552,327 - 86,731,081 (+)NCBIT2T-CHM13v2.0
Slc24a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,094,986 - 102,239,562 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12102,094,992 - 102,233,350 (+)EnsemblGRCm39 Ensembl
GRCm3812102,128,727 - 102,267,133 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,128,733 - 102,267,091 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712103,367,629 - 103,504,959 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612102,530,469 - 102,667,799 (+)NCBIMGSCv36mm8
Celera12103,346,630 - 103,484,305 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.42NCBI
Slc24a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,044,470 - 127,184,684 (+)NCBIGRCr8
mRatBN7.26121,279,590 - 121,419,811 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,280,031 - 121,414,949 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6121,421,469 - 121,560,529 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06121,716,729 - 121,855,788 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,053,045 - 121,191,790 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,015,799 - 126,158,727 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,018,841 - 126,153,867 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06135,226,112 - 135,364,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46126,403,837 - 126,538,501 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16126,300,244 - 126,541,897 (+)NCBI
Celera6118,769,531 - 118,903,571 (+)NCBICelera
Cytogenetic Map6q32NCBI
Slc24a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543814,609,424 - 14,759,673 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543814,609,779 - 14,765,516 (+)NCBIChiLan1.0ChiLan1.0
SLC24A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21593,480,347 - 93,659,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11492,696,423 - 92,875,680 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,956,230 - 73,128,851 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11492,299,467 - 92,471,426 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,299,507 - 92,468,939 (+)Ensemblpanpan1.1panPan2
SLC24A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,570,833 - 1,685,135 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,517,560 - 1,680,208 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha81,539,853 - 1,708,276 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.081,570,067 - 1,738,485 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl81,567,138 - 1,740,126 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.181,507,888 - 1,676,257 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,464,369 - 1,626,873 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.081,585,200 - 1,753,590 (+)NCBIUU_Cfam_GSD_1.0
Slc24a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,828,736 - 12,951,485 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936733515,510 - 639,705 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936733515,546 - 639,699 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC24A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7113,836,230 - 114,014,949 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17113,836,207 - 114,014,952 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,439,442 - 120,621,231 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC24A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,068,924 - 70,242,148 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,179,850 - 70,239,517 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605357,318,844 - 57,493,322 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000018685   ⟹   ENSHGLP00000018501
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247348,911,455 - 9,063,063 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000018686   ⟹   ENSHGLP00000018502
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247349,011,162 - 9,061,974 (+)Ensembl
RefSeq Acc Id: XM_004837023   ⟹   XP_004837080
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247348,911,376 - 9,069,054 (+)NCBI
RefSeq Acc Id: XM_004837024   ⟹   XP_004837081
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247348,911,376 - 9,069,054 (+)NCBI
RefSeq Acc Id: XM_021244813   ⟹   XP_021100472
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247348,911,376 - 9,069,054 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004837080 (Get FASTA)   NCBI Sequence Viewer  
  XP_004837081 (Get FASTA)   NCBI Sequence Viewer  
  XP_021100472 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018501
RefSeq Acc Id: XP_004837080   ⟸   XM_004837023
- Peptide Label: isoform X1
- UniProtKB: G5BK99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004837081   ⟸   XM_004837024
- Peptide Label: isoform X2
- UniProtKB: G5BK99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100472   ⟸   XM_021244813
- Peptide Label: isoform X3
- UniProtKB: G5BK99 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018501   ⟸   ENSHGLT00000018685
Ensembl Acc Id: ENSHGLP00000018502   ⟸   ENSHGLT00000018686


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013245 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000018685 ENTREZGENE
Gene3D-CATH NCX, central ion-binding region UniProtKB/TrEMBL
InterPro K/Na/Ca-exchanger UniProtKB/TrEMBL
  NaCa_Exmemb UniProtKB/TrEMBL
  NCX_ion-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene Slc24a4 ENTREZGENE
PANTHER SODIUM/POTASSIUM/CALCIUM EXCHANGER UniProtKB/TrEMBL
  SODIUM/POTASSIUM/CALCIUM EXCHANGER 4 UniProtKB/TrEMBL
Pfam Na_Ca_ex UniProtKB/TrEMBL
UniProt A0AAX6NUB0_HETGA UniProtKB/TrEMBL
  A0AAX6NUF2_HETGA UniProtKB/TrEMBL
  A0AAX6RV19_HETGA UniProtKB/TrEMBL
  G5BK99 ENTREZGENE, UniProtKB/TrEMBL