Cgref1 (cell growth regulator with EF-hand domain 1) - Rat Genome Database

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Gene: Cgref1 (cell growth regulator with EF-hand domain 1) Heterocephalus glaber
Analyze
Symbol: Cgref1
Name: cell growth regulator with EF-hand domain 1
RGD ID: 18901792
Description: ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH essential fructosuria (ortholog); genetic disease (ortholog); Liver Neoplasms (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cell growth regulator with EF hand domain protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247389,203,367 - 9,216,309 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247389,203,367 - 9,216,485 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Cgref1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247389,203,367 - 9,216,309 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247389,203,367 - 9,216,485 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CGREF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38227,099,353 - 27,119,128 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl227,098,889 - 27,119,128 (-)EnsemblGRCh38hg38GRCh38
GRCh37227,322,221 - 27,341,996 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36227,176,973 - 27,195,475 (-)NCBINCBI36Build 36hg18NCBI36
Build 34227,235,119 - 27,253,622NCBI
Celera227,168,567 - 27,188,302 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef227,064,526 - 27,084,159 (-)NCBIHuRef
CHM1_1227,252,137 - 27,271,942 (-)NCBICHM1_1
T2T-CHM13v2.0227,141,029 - 27,160,791 (-)NCBIT2T-CHM13v2.0
Cgref1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39531,090,487 - 31,102,771 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl531,090,487 - 31,102,935 (-)EnsemblGRCm39 Ensembl
GRCm38530,933,143 - 30,945,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,933,143 - 30,945,591 (-)EnsemblGRCm38mm10GRCm38
MGSCv37531,235,516 - 31,247,853 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36531,209,724 - 31,222,166 (-)NCBIMGSCv36mm8
Celera528,412,941 - 28,425,273 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.9NCBI
Cgref1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,151,795 - 31,163,801 (+)NCBIGRCr8
mRatBN7.2625,431,846 - 25,443,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,431,799 - 25,443,852 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx625,732,163 - 25,744,167 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,048,027 - 26,060,031 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,527,201 - 25,539,214 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,797,126 - 26,809,132 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,797,126 - 26,809,129 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,612,741 - 36,624,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,414,812 - 25,426,818 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1625,417,842 - 25,429,770 (+)NCBI
Celera624,922,567 - 24,934,501 (+)NCBICelera
RH 3.4 Map6119.2RGD
Cytogenetic Map6q14NCBI
Cgref1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554699,072,563 - 9,086,615 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554699,072,333 - 9,086,427 (-)NCBIChiLan1.0ChiLan1.0
CGREF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,396,407 - 99,415,823 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,400,376 - 99,419,791 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,098,387 - 27,118,129 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A27,189,151 - 27,207,263 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A27,188,352 - 27,199,407 (-)Ensemblpanpan1.1panPan2
CGREF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11721,093,664 - 21,106,797 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1720,985,489 - 20,998,849 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01721,414,345 - 21,427,720 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,413,017 - 21,427,705 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11721,101,095 - 21,114,500 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01721,112,197 - 21,125,293 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01721,159,031 - 21,161,865 (-)NCBIUU_Cfam_GSD_1.0
Cgref1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,395,880 - 65,410,272 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,429,131 - 5,442,965 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,429,397 - 5,444,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CGREF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.13112,006,596 - 112,020,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,000,618 - 119,018,207 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CGREF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,500,056 - 80,516,893 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,513,701 - 80,516,698 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,622,380 - 31,639,353 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004839165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01015634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000024104   ⟹   ENSHGLP00000023886
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247389,203,367 - 9,216,309 (-)Ensembl
RefSeq Acc Id: XM_004839165   ⟹   XP_004839222
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247389,203,367 - 9,216,485 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004839222 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023886
Reference Protein Sequences
RefSeq Acc Id: XP_004839222   ⟸   XM_004839165
- UniProtKB: G5BYZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000023886   ⟸   ENSHGLT00000024104


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017028 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024104 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene Cgref1 ENTREZGENE
PANTHER CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1 UniProtKB/TrEMBL
  MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
Superfamily-SCOP EF-hand UniProtKB/TrEMBL
UniProt G5BYZ3 ENTREZGENE, UniProtKB/TrEMBL