Chd8 (chromodomain helicase DNA binding protein 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Chd8 (chromodomain helicase DNA binding protein 8) Heterocephalus glaber
Analyze
Symbol: Chd8
Name: chromodomain helicase DNA binding protein 8
RGD ID: 18901785
Description: ENCODES a protein that exhibits armadillo repeat domain binding (ortholog); INVOLVED IN brain development (ortholog); digestive tract development (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN MLL1 complex (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromodomain-helicase-DNA-binding protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,411,629 - 7,474,526 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,411,629 - 7,475,111 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Chd8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,411,629 - 7,474,526 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,411,629 - 7,475,111 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CHD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381421,385,199 - 21,456,123 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1421,385,194 - 21,456,126 (-)EnsemblGRCh38hg38GRCh38
GRCh371421,853,358 - 21,924,282 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,923,198 - 20,975,244 (-)NCBINCBI36Build 36hg18NCBI36
Celera141,718,849 - 1,770,858 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,973,207 - 2,025,186 (-)NCBIHuRef
CHM1_11421,855,022 - 21,906,934 (-)NCBICHM1_1
T2T-CHM13v2.01415,582,676 - 15,653,513 (-)NCBIT2T-CHM13v2.0
Chd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391452,435,608 - 52,495,499 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1452,435,608 - 52,495,237 (-)EnsemblGRCm39 Ensembl
GRCm381452,198,151 - 52,258,042 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1452,198,151 - 52,257,780 (-)EnsemblGRCm38mm10GRCm38
MGSCv371452,817,826 - 52,857,247 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361451,120,096 - 51,159,523 (-)NCBIMGSCv36mm8
Celera1449,182,118 - 49,221,458 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1426.84NCBI
Chd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81527,379,285 - 27,438,959 (-)NCBIGRCr8
mRatBN7.21524,905,789 - 24,965,461 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,905,789 - 24,951,285 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,678,019 - 27,716,742 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,632,597 - 28,671,160 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,885,536 - 26,924,098 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,612,932 - 28,672,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,612,932 - 28,672,569 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01532,423,198 - 32,482,762 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,642,767 - 27,704,443 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,684,891 - 27,696,816 (-)NCBI
Celera1525,209,591 - 25,269,314 (-)NCBICelera
Cytogenetic Map15p14NCBI
Chd8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555502,115,649 - 2,175,181 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555502,115,649 - 2,175,687 (-)NCBIChiLan1.0ChiLan1.0
CHD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,840,472 - 22,911,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11422,056,959 - 22,128,117 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,202,847 - 2,274,012 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11420,281,422 - 20,326,361 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1420,281,422 - 20,326,361 (-)Ensemblpanpan1.1panPan2
CHD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,430,601 - 18,492,564 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,431,019 - 18,491,920 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,915,263 - 18,977,048 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,689,452 - 18,730,186 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,689,459 - 18,736,281 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11518,371,825 - 18,433,622 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,427,678 - 18,489,656 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,556,498 - 18,618,517 (-)NCBIUU_Cfam_GSD_1.0
Chd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,636,869 - 32,698,700 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936880546,236 - 608,080 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936880546,250 - 608,061 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHD8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl777,719,582 - 77,780,146 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1777,719,476 - 77,780,148 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,061,334 - 83,121,484 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHD8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,856,434 - 21,924,761 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,856,263 - 21,924,787 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605924,505,797 - 24,574,122 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000004910   ⟹   ENSHGLP00000004846
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248257,411,629 - 7,474,526 (-)Ensembl
RefSeq Acc Id: XM_013065682   ⟹   XP_012921136
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,411,629 - 7,474,547 (-)NCBI
RefSeq Acc Id: XM_013065683   ⟹   XP_012921137
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,411,629 - 7,474,547 (-)NCBI
RefSeq Acc Id: XM_021244555   ⟹   XP_021100214
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,411,629 - 7,475,111 (-)NCBI
RefSeq Acc Id: XM_021244556   ⟹   XP_021100215
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,411,629 - 7,461,546 (-)NCBI
RefSeq Acc Id: XM_021244557   ⟹   XP_021100216
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,411,629 - 7,474,501 (-)NCBI
RefSeq Acc Id: XM_021244558   ⟹   XP_021100217
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,412,050 - 7,455,502 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021100214   ⟸   XM_021244555
- Peptide Label: isoform X1
- UniProtKB: G5BFV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012921137   ⟸   XM_013065683
- Peptide Label: isoform X3
- UniProtKB: G5BFV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012921136   ⟸   XM_013065682
- Peptide Label: isoform X1
- UniProtKB: G5BFV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100216   ⟸   XM_021244557
- Peptide Label: isoform X1
- UniProtKB: G5BFV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100215   ⟸   XM_021244556
- Peptide Label: isoform X1
- UniProtKB: G5BFV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100217   ⟸   XM_021244558
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JVY2 (UniProtKB/TrEMBL),   G5BFV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000004846   ⟸   ENSHGLT00000004910


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003559 Ensembl, ENTREZGENE
  ENSHGLG00100001031 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000004910 ENTREZGENE
  ENSHGLT00100001336 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
  3.40.5.120 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro BRK_domain UniProtKB/TrEMBL
  BRK_sf UniProtKB/TrEMBL
  CHD8 UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
KEGG Report hgl:101698950 UniProtKB/TrEMBL
NCBI Gene Chd8 ENTREZGENE
PANTHER CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 UniProtKB/TrEMBL
  DNA HELICASE UniProtKB/TrEMBL
Pfam BRK UniProtKB/TrEMBL
  Chromo UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
PROSITE CHROMO_2 UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART BRK UniProtKB/TrEMBL
  CHROMO UniProtKB/TrEMBL
  DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF160481 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF54160 UniProtKB/TrEMBL
UniProt A0A0P6JVY2 ENTREZGENE, UniProtKB/TrEMBL
  G5BFV2 ENTREZGENE, UniProtKB/TrEMBL