Tsku (tsukushi, small leucine rich proteoglycan) - Rat Genome Database

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Gene: Tsku (tsukushi, small leucine rich proteoglycan) Heterocephalus glaber
Analyze
Symbol: Tsku
Name: tsukushi, small leucine rich proteoglycan
RGD ID: 18901703
Description: ENCODES a protein that exhibits transforming growth factor beta binding (ortholog); INVOLVED IN anterior commissure morphogenesis (ortholog); camera-type eye development (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tsukushin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624817366,101 - 373,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624817364,543 - 379,742 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tsku
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624817366,101 - 373,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624817364,543 - 379,742 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TSKU
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381176,782,280 - 76,798,144 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1176,782,251 - 76,798,153 (+)EnsemblGRCh38hg38GRCh38
GRCh371176,493,324 - 76,509,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361176,171,933 - 76,186,846 (+)NCBINCBI36Build 36hg18NCBI36
Celera1173,801,738 - 73,816,651 (+)NCBICelera
Cytogenetic Map11q13.5NCBI
HuRef1172,791,056 - 72,806,897 (+)NCBIHuRef
CHM1_11176,376,410 - 76,392,251 (+)NCBICHM1_1
T2T-CHM13v2.01176,712,593 - 76,728,455 (+)NCBIT2T-CHM13v2.0
Tsku
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39797,999,875 - 98,010,602 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl797,999,875 - 98,010,535 (-)EnsemblGRCm39 Ensembl
GRCm38798,350,668 - 98,361,390 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,350,668 - 98,361,328 (-)EnsemblGRCm38mm10GRCm38
MGSCv377105,499,178 - 105,509,838 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36798,226,060 - 98,236,480 (-)NCBIMGSCv36mm8
Celera798,670,613 - 98,681,273 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.66NCBI
Tsku
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81162,071,459 - 162,082,972 (-)NCBIGRCr8
mRatBN7.21152,660,259 - 152,671,682 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1152,656,693 - 152,672,588 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1160,648,580 - 160,659,888 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,828,744 - 167,840,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01160,702,272 - 160,713,580 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01163,317,281 - 163,328,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,317,282 - 163,328,591 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,524,020 - 169,535,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,611,069 - 155,622,378 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11155,689,480 - 155,700,780 (-)NCBI
Celera1150,750,146 - 150,761,455 (-)NCBICelera
Cytogenetic Map1q32NCBI
Tsku
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541415,166,349 - 15,178,284 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541415,166,349 - 15,178,284 (-)NCBIChiLan1.0ChiLan1.0
TSKU
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2977,704,718 - 77,719,598 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,750,093 - 78,764,950 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01171,833,654 - 71,848,509 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11175,480,674 - 75,495,449 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1175,492,912 - 75,493,973 (+)Ensemblpanpan1.1panPan2
TSKU
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12121,910,333 - 21,927,758 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2121,915,956 - 21,928,119 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2121,743,504 - 21,757,126 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02122,116,699 - 22,130,306 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2122,116,701 - 22,130,823 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12121,887,862 - 21,901,417 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02122,107,232 - 22,120,834 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02122,030,572 - 22,044,179 (-)NCBIUU_Cfam_GSD_1.0
Tsku
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,835,116 - 63,887,751 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364985,434,911 - 5,447,147 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364985,434,912 - 5,487,354 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSKU
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,927,342 - 10,942,668 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,927,224 - 10,940,851 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2912,036,689 - 12,050,312 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSKU
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,988,729 - 68,003,959 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl168,001,429 - 68,002,490 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604357,785,591 - 57,800,748 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027594   ⟹   ENSHGLP00000027352
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624817366,101 - 373,034 (-)Ensembl
RefSeq Acc Id: XM_004863197   ⟹   XP_004863254
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624817364,543 - 379,742 (-)NCBI
RefSeq Acc Id: XM_004863199   ⟹   XP_004863256
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624817364,543 - 378,846 (-)NCBI
RefSeq Acc Id: XM_004863200   ⟹   XP_004863257
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624817364,543 - 377,970 (-)NCBI
RefSeq Acc Id: XM_004863201   ⟹   XP_004863258
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624817364,543 - 378,006 (-)NCBI
RefSeq Acc Id: XM_004863202   ⟹   XP_004863259
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624817364,543 - 378,730 (-)NCBI
RefSeq Acc Id: XM_021243229   ⟹   XP_021098888
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624817364,543 - 373,591 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004863254   ⟸   XM_004863197
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004863256   ⟸   XM_004863199
- Peptide Label: isoform X2
- UniProtKB: G5AW83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863259   ⟸   XM_004863202
- Peptide Label: isoform X2
- UniProtKB: G5AW83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863258   ⟸   XM_004863201
- Peptide Label: isoform X2
- UniProtKB: G5AW83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863257   ⟸   XM_004863200
- Peptide Label: isoform X2
- UniProtKB: G5AW83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098888   ⟸   XM_021243229
- Peptide Label: isoform X2
- UniProtKB: G5AW83 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000027352   ⟸   ENSHGLT00000027594


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019448 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027594 ENTREZGENE
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Tsku ENTREZGENE
PANTHER LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 6 UniProtKB/TrEMBL
  SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt G5AW83 ENTREZGENE, UniProtKB/TrEMBL