Gpr27 (G protein-coupled receptor 27)

Gene: Gpr27 (G protein-coupled receptor 27) Heterocephalus glaber

Analyze

Symbol:

Gpr27

Name:

G protein-coupled receptor 27

RGD ID:

18901388

Description:

INVOLVED IN positive regulation of insulin secretion involved in cellular response to glucose stimulus (ortholog); positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); malignant mesothelioma (ortholog); FOUND IN plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

probable G-protein coupled receptor 27

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624773	6,294,850 - 6,296,010 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624773	6,294,850 - 6,297,249 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

malignant mesothelioma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of insulin secretion involved in cellular response to glucose stimulus (ISO)

positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (ISO)

Cellular Component

plasma membrane (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Gpr27
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624773	6,294,850 - 6,296,010 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624773	6,294,850 - 6,297,249 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

GPR27
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	71,753,855 - 71,756,496 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	71,753,855 - 71,756,496 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	71,803,006 - 71,805,647 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	71,885,891 - 71,887,018 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	71,885,890 - 71,887,018	NCBI
Celera	3	71,733,794 - 71,734,921 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI
CHM1_1	3	71,754,610 - 71,755,737 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	71,793,122 - 71,795,766 (+)	NCBI		T2T-CHM13v2.0

Gpr27
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	99,669,328 - 99,672,027 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	99,669,640 - 99,672,027 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	99,692,367 - 99,695,066 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	99,692,679 - 99,695,066 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	99,642,673 - 99,643,812 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	99,658,142 - 99,659,281 (+)	NCBI		MGSCv36	mm8
Celera	6	101,556,763 - 101,557,942 (+)	NCBI		Celera
Cytogenetic Map	6	D3	NCBI
cM Map	6	46.22	NCBI

Gpr27
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	133,884,894 - 133,886,027 (+)	NCBI		GRCr8
mRatBN7.2	4	132,328,364 - 132,329,497 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	132,328,364 - 132,329,497 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	137,745,693 - 137,746,826 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	133,526,475 - 133,527,608 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	132,144,746 - 132,145,879 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	132,137,793 - 132,138,926 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	132,137,793 - 132,138,926 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	196,629,031 - 196,630,164 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	134,541,534 - 134,542,667 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	134,786,374 - 134,787,508 (+)	NCBI
Celera	4	121,187,535 - 121,188,668 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Gpr27
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955421	16,352,643 - 16,353,094 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR27
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	71,713,162 - 71,715,808 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	71,717,950 - 71,720,596 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	71,693,611 - 71,696,247 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	73,050,542 - 73,052,347 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

GPR27
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	20	20,249,117 - 20,251,750 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	20,307,618 - 20,309,127 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	20,307,969 - 20,309,117 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	19,992,950 - 19,995,575 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	20,342,113 - 20,344,735 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	20,408,115 - 20,410,754 (-)	NCBI		UU_Cfam_GSD_1.0

Gpr27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	3,284,932 - 3,289,003 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936603	3,241,741 - 3,289,996 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR27
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	53,152,062 - 53,153,192 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	53,152,038 - 53,154,537 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

GPR27
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	32,708,228 - 32,709,820 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	32,708,599 - 32,709,729 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	134,068,927 - 134,071,765 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_004854205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01051783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSHGLT00000003541 ⟹ ENSHGLP00000003486

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624773	6,294,850 - 6,296,010 (+)	Ensembl

RefSeq Acc Id:

XM_004854205 ⟹ XP_004854262

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624773	6,294,850 - 6,297,249 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_004854262	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_004854262 ⟸ XM_004854205

RefSeq Acc Id:

ENSHGLP00000003486 ⟸ ENSHGLT00000003541

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000002574	Ensembl
NCBI Gene	Gpr27	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD