Hrob (homologous recombination factor with OB-fold) - Rat Genome Database

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Gene: Hrob (homologous recombination factor with OB-fold) Heterocephalus glaber
Analyze
Symbol: Hrob
Name: homologous recombination factor with OB-fold
RGD ID: 18901015
Description: ENCODES a protein that exhibits single-stranded DNA binding (ortholog); INVOLVED IN DNA damage response (ortholog); DNA synthesis involved in DNA repair (ortholog); female gamete generation (ortholog); ASSOCIATED WITH GRN-related frontotemporal lobar degeneration with TDP43 inclusions (ortholog); primary ovarian insufficiency (ortholog); FOUND IN site of DNA damage (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromosome unknown C17orf53 homolog; CUNH17orf53; homologous recombincation factor with OB-fold; uncharacterized protein C17orf53 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624795799,533 - 806,876 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hrob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624795799,533 - 806,876 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HROB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381744,141,930 - 44,162,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1744,141,906 - 44,162,476 (+)EnsemblGRCh38hg38GRCh38
GRCh371742,219,298 - 42,239,844 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361739,574,852 - 39,595,369 (+)NCBINCBI36Build 36hg18NCBI36
Celera1738,927,986 - 38,948,557 (+)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1737,983,300 - 38,003,871 (+)NCBIHuRef
CHM1_11742,454,660 - 42,475,226 (+)NCBICHM1_1
T2T-CHM13v2.01744,995,027 - 45,015,576 (+)NCBIT2T-CHM13v2.0
Hrob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,139,677 - 102,156,009 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11102,139,708 - 102,156,013 (+)EnsemblGRCm39 Ensembl
GRCm3811102,248,857 - 102,265,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11102,248,882 - 102,265,187 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711102,110,196 - 102,126,497 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,064,975 - 102,081,268 (+)NCBIMGSCv36mm8
Celera11113,955,724 - 113,972,051 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1166.21NCBI
Hrob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81087,705,846 - 87,722,635 (+)NCBIGRCr8
mRatBN7.21087,206,017 - 87,222,483 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1087,206,049 - 87,222,483 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1092,235,757 - 92,252,069 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01091,707,723 - 91,724,057 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01087,101,040 - 87,117,376 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01090,192,608 - 90,214,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1090,192,627 - 90,214,486 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,978,419 - 90,001,064 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,329,706 - 91,347,594 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11091,344,075 - 91,361,964 (+)NCBI
Celera1085,922,100 - 85,938,261 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Hrob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545117,256,593 - 17,264,872 (+)NCBIChiLan1.0ChiLan1.0
HROB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21920,744,231 - 20,767,556 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11722,708,577 - 22,731,897 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01713,233,464 - 13,254,726 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11713,395,473 - 13,415,346 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1713,395,473 - 13,409,505 (-)Ensemblpanpan1.1panPan2
HROB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1919,230,345 - 19,245,518 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl919,230,399 - 19,245,624 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha918,621,143 - 18,636,309 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0919,926,089 - 19,941,286 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl919,926,137 - 19,941,347 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1918,779,466 - 18,794,637 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0918,962,526 - 18,977,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,107,482 - 19,122,654 (-)NCBIUU_Cfam_GSD_1.0
Hrob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560218,559,665 - 18,575,134 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936541620,754 - 633,499 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936541619,120 - 633,590 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HROB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,044,043 - 19,077,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11219,044,569 - 19,077,877 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21219,338,655 - 19,344,491 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HROB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11662,230,588 - 62,251,090 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1662,230,261 - 62,250,734 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607732,998,346 - 33,023,368 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021240212   ⟹   XP_021095871
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624795799,533 - 806,876 (-)NCBI
RefSeq Acc Id: XM_021240213   ⟹   XP_021095872
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624795799,533 - 806,876 (-)NCBI
RefSeq Acc Id: XM_021240214   ⟹   XP_021095873
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624795799,533 - 805,735 (-)NCBI
RefSeq Acc Id: XM_021240215   ⟹   XP_021095874
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624795799,682 - 806,876 (-)NCBI
RefSeq Acc Id: XM_021240216   ⟹   XP_021095875
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624795799,832 - 806,876 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021095872   ⟸   XM_021240213
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021095871   ⟸   XM_021240212
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021095873   ⟸   XM_021240214
- Peptide Label: isoform X3
- UniProtKB: G5BN72 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021095874   ⟸   XM_021240215
- Peptide Label: isoform X4
- UniProtKB: G5BN72 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021095875   ⟸   XM_021240216
- Peptide Label: isoform X5
- UniProtKB: G5BN72 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
InterPro HROB UniProtKB/TrEMBL
NCBI Gene Hrob ENTREZGENE
PANTHER HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN UniProtKB/TrEMBL
  UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG UniProtKB/TrEMBL
Pfam HROB UniProtKB/TrEMBL
UniProt G5BN72 ENTREZGENE, UniProtKB/TrEMBL