Dnmt3l (DNA methyltransferase 3 like) - Rat Genome Database

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Gene: Dnmt3l (DNA methyltransferase 3 like) Heterocephalus glaber
Analyze
Symbol: Dnmt3l
Name: DNA methyltransferase 3 like
RGD ID: 18900847
Description: ENCODES a protein that exhibits DNA (cytosine-5-)-methyltransferase activity (ortholog); enzyme binding (ortholog); INVOLVED IN autosome genomic imprinting (ortholog); chorionic trophoblast cell differentiation (ortholog); DNA methylation-dependent heterochromatin formation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autoimmune polyendocrine syndrome type 1 (ortholog); cataract 9 multiple types (ortholog); FOUND IN catalytic complex (ortholog); condensed nuclear chromosome (ortholog); ESC/E(Z) complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA (cytosine-5)-methyltransferase 3-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474529,869,196 - 29,878,169 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474529,869,174 - 29,878,189 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dnmt3l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474529,869,196 - 29,878,169 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474529,869,174 - 29,878,189 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DNMT3L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382144,246,339 - 44,261,897 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2144,246,339 - 44,262,216 (-)EnsemblGRCh38hg38GRCh38
GRCh372145,666,222 - 45,681,780 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,490,651 - 44,506,527 (-)NCBINCBI36Build 36hg18NCBI36
Build 342144,490,650 - 44,506,527NCBI
Celera2130,771,480 - 30,787,356 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2131,036,675 - 31,052,591 (-)NCBIHuRef
CHM1_12145,226,863 - 45,242,733 (-)NCBICHM1_1
T2T-CHM13v2.02142,600,400 - 42,615,957 (-)NCBIT2T-CHM13v2.0
Dnmt3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,878,121 - 77,899,456 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1077,877,781 - 77,899,456 (+)EnsemblGRCm39 Ensembl
GRCm381078,042,287 - 78,063,622 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,041,947 - 78,063,622 (+)EnsemblGRCm38mm10GRCm38
MGSCv371077,505,032 - 77,526,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361077,452,971 - 77,466,744 (+)NCBIMGSCv36mm8
Celera1079,081,287 - 79,102,649 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Dnmt3l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82010,614,591 - 10,628,989 (-)NCBIGRCr8
mRatBN7.22010,614,933 - 10,629,337 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2010,614,934 - 10,629,516 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2011,314,285 - 11,328,650 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02010,675,187 - 10,689,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02011,147,204 - 11,161,604 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02011,344,513 - 11,359,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,344,514 - 11,359,090 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,514,653 - 13,529,169 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,958,957 - 10,973,422 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12010,959,183 - 10,973,649 (-)NCBI
Celera2012,120,702 - 12,135,281 (-)NCBICelera
Cytogenetic Map20p12NCBI
Dnmt3l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,177,582 - 41,186,965 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540741,177,582 - 41,186,965 (+)NCBIChiLan1.0ChiLan1.0
DNMT3L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22240,255,079 - 40,269,622 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12135,105,200 - 35,119,723 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02130,503,194 - 30,520,237 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12143,798,778 - 43,814,283 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2143,798,778 - 43,814,283 (-)Ensemblpanpan1.1panPan2
DNMT3L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13138,099,100 - 38,111,432 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3137,256,521 - 37,272,413 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03137,646,747 - 37,659,063 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3137,645,326 - 37,659,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13137,513,901 - 37,526,213 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03137,497,879 - 37,510,191 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,992,522 - 38,008,421 (-)NCBIUU_Cfam_GSD_1.0
Dnmt3l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497137,307,350 - 37,324,745 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936500143,078 - 160,212 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936500143,078 - 160,318 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNMT3L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13207,119,051 - 207,132,538 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113207,119,025 - 207,141,990 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213216,998,088 - 217,011,839 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNMT3L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1287,991,868 - 88,006,399 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl287,991,936 - 88,005,459 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605416,105,634 - 16,119,773 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013364   ⟹   ENSHGLP00000013225
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474529,869,196 - 29,878,169 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000013365   ⟹   ENSHGLP00000013226
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474529,869,808 - 29,878,160 (+)Ensembl
RefSeq Acc Id: XM_004842591   ⟹   XP_004842648
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474529,869,174 - 29,878,189 (+)NCBI
RefSeq Acc Id: XM_021256378   ⟹   XP_021112037
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474529,869,174 - 29,878,189 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004842648 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112037 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021112037   ⟸   XM_021256378
- Peptide Label: isoform X1
- UniProtKB: G5BG15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842648   ⟸   XM_004842591
- Peptide Label: isoform X2
- UniProtKB: G5BG15 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000013226   ⟸   ENSHGLT00000013365
RefSeq Acc Id: ENSHGLP00000013225   ⟸   ENSHGLT00000013364


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009448 Ensembl
Gene3D-CATH Vaccinia Virus protein VP39 UniProtKB/TrEMBL
InterPro ADD UniProtKB/TrEMBL
  DNMT3_ADD UniProtKB/TrEMBL
  DNMT3_ADD_PHD UniProtKB/TrEMBL
  SAM-dependent_MTases_sf UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
NCBI Gene Dnmt3l ENTREZGENE
PANTHER DNA (CYTOSINE-5)-METHYLTRANSFERASE 3-LIKE UniProtKB/TrEMBL
  DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED UniProtKB/TrEMBL
Pfam ADD_DNMT3 UniProtKB/TrEMBL
  ADDz_Dnmt3b UniProtKB/TrEMBL
PROSITE ADD UniProtKB/TrEMBL
Superfamily-SCOP FYVE/PHD zinc finger UniProtKB/TrEMBL
UniProt G5BG15 ENTREZGENE, UniProtKB/TrEMBL