Oxt (oxytocin/neurophysin I prepropeptide) - Rat Genome Database

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Gene: Oxt (oxytocin/neurophysin I prepropeptide) Heterocephalus glaber
Analyze
Symbol: Oxt
Name: oxytocin/neurophysin I prepropeptide
RGD ID: 18900417
Description: ENCODES a protein that exhibits neuropeptide hormone activity (ortholog); oxytocin receptor binding (ortholog); INVOLVED IN drinking behavior (ortholog); eating behavior (ortholog); female pregnancy (ortholog); PARTICIPATES IN oxytocin signaling pathway; ASSOCIATED WITH anxiety disorder (ortholog); autistic disorder (ortholog); Burns (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: oxytocin-neurophysin 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,200,478 - 4,201,580 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,200,594 - 4,201,416 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
drinking behavior  (ISO)
eating behavior  (ISO)
female pregnancy  (ISO)
grooming behavior  (ISO)
heart development  (ISO)
male mating behavior  (ISO)
maternal aggressive behavior  (ISO)
maternal behavior  (ISO)
memory  (ISO)
negative regulation of blood pressure  (ISO)
negative regulation of urine volume  (ISO)
positive regulation of blood pressure  (ISO)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of female receptivity  (ISO)
positive regulation of hindgut contraction  (ISO)
positive regulation of norepinephrine secretion  (ISO)
positive regulation of ossification  (ISO)
positive regulation of penile erection  (ISO)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of synapse assembly  (ISO)
positive regulation of synaptic transmission  (ISO)
positive regulation of uterine smooth muscle contraction  (ISO)
regulation of heart rate  (ISO)
response to activity  (ISO)
response to amphetamine  (ISO)
response to cAMP  (ISO)
response to cocaine  (ISO)
response to electrical stimulus  (ISO)
response to estradiol  (ISO)
response to ether  (ISO)
response to food  (ISO)
response to genistein  (ISO)
response to glucocorticoid  (ISO)
response to peptide hormone  (ISO)
response to progesterone  (ISO)
response to prostaglandin E  (ISO)
response to retinoic acid  (ISO)
response to steroid hormone  (ISO)
response to sucrose  (ISO)
social behavior  (ISO)
sperm ejaculation  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Oxt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,200,478 - 4,201,580 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,200,594 - 4,201,416 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
OXT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,071,620 - 3,072,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,071,620 - 3,072,517 (+)EnsemblGRCh38hg38GRCh38
GRCh37203,052,266 - 3,053,163 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,000,266 - 3,001,162 (+)NCBINCBI36Build 36hg18NCBI36
Build 34203,000,265 - 3,001,162NCBI
Celera203,114,251 - 3,115,147 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef202,998,607 - 2,999,505 (+)NCBIHuRef
CHM1_1203,046,806 - 3,047,704 (+)NCBICHM1_1
T2T-CHM13v2.0203,099,764 - 3,103,415 (+)NCBIT2T-CHM13v2.0
Oxt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,416,432 - 130,418,974 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,418,093 - 130,418,974 (+)EnsemblGRCm39 Ensembl
GRCm382130,574,519 - 130,577,054 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,576,173 - 130,577,054 (+)EnsemblGRCm38mm10GRCm38
MGSCv372130,401,909 - 130,402,724 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,267,614 - 130,268,429 (+)NCBIMGSCv36mm8
Celera2131,800,597 - 131,801,412 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.24NCBI
Oxt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,235,754 - 138,236,594 (+)NCBIGRCr8
mRatBN7.23117,782,650 - 117,783,490 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,782,650 - 117,783,490 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,677,109 - 121,677,940 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,274,375 - 130,275,205 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,933,240 - 127,934,071 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,106,694 - 123,107,534 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,106,694 - 123,107,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,604,822 - 129,605,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,194,219 - 118,195,056 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,097,303 - 118,100,512 (+)NCBI
Celera3116,593,509 - 116,594,349 (+)NCBICelera
Cytogenetic Map3q36NCBI
OXT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,039,169 - 4,040,042 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,034,732 - 4,036,865 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,157,246 - 3,159,013 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
OXT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,193,381 - 18,194,232 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,193,339 - 18,194,170 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,021,790 - 18,022,393 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,612,328 - 18,612,968 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,612,281 - 18,613,193 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,205,647 - 18,206,253 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,318,339 - 18,318,942 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,646,119 - 18,646,759 (-)NCBIUU_Cfam_GSD_1.0
OXT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,605,586 - 32,606,546 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,605,586 - 32,606,449 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,975,726 - 36,976,589 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OXT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,749,520 - 33,750,981 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl233,750,108 - 33,750,968 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,763,922 - 10,764,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004840694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01018865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000021858   ⟹   ENSHGLP00000021648
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247414,200,478 - 4,201,580 (+)Ensembl
RefSeq Acc Id: XM_004840694   ⟹   XP_004840751
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,200,594 - 4,201,416 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004840751 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021648
RefSeq Acc Id: XP_004840751   ⟸   XM_004840694
Ensembl Acc Id: ENSHGLP00000021648   ⟸   ENSHGLT00000021858


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015471 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021858 ENTREZGENE
NCBI Gene Oxt ENTREZGENE
UniProt A0AAX6P069_HETGA UniProtKB/TrEMBL