Dact3 (dishevelled binding antagonist of beta catenin 3) - Rat Genome Database

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Gene: Dact3 (dishevelled binding antagonist of beta catenin 3) Heterocephalus glaber
Analyze
Symbol: Dact3
Name: dishevelled binding antagonist of beta catenin 3
RGD ID: 18900174
Description: ENCODES a protein that exhibits delta-catenin binding (ortholog); identical protein binding (ortholog); protein kinase A binding (ortholog); INVOLVED IN canonical Wnt signaling pathway (ortholog); epithelial to mesenchymal transition (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); long QT syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dapper homolog 3; guanine nucleotide binding protein (G protein), gamma 8
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,921,148 - 6,929,587 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,920,984 - 6,930,391 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dact3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,921,148 - 6,929,587 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,920,984 - 6,930,391 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DACT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,647,551 - 46,661,182 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,647,551 - 46,661,182 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,150,808 - 47,164,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,842,709 - 51,849,754 (-)NCBINCBI36Build 36hg18NCBI36
Celera1943,954,390 - 43,967,921 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,575,796 - 43,589,524 (-)NCBIHuRef
CHM1_11947,152,719 - 47,166,253 (-)NCBICHM1_1
T2T-CHM13v2.01949,473,085 - 49,486,718 (-)NCBIT2T-CHM13v2.0
Dact3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,609,242 - 16,621,226 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,609,242 - 16,621,387 (+)EnsemblGRCm39 Ensembl
GRCm38716,875,317 - 16,887,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,875,317 - 16,887,462 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,460,666 - 17,472,650 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36717,460,666 - 17,472,650 (+)NCBIMGSCv36mm8
Celera714,081,734 - 14,093,719 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Dact3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,674,989 - 86,686,722 (+)NCBIGRCr8
mRatBN7.2177,546,900 - 77,558,631 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,546,900 - 77,558,630 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,926,980 - 82,938,814 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,491,025 - 91,502,859 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,682,071 - 84,693,905 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,800,754 - 78,812,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,800,754 - 78,812,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0180,048,066 - 80,059,888 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,201,808 - 77,213,537 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera172,031,999 - 72,043,732 (+)NCBICelera
Cytogenetic Map1q21NCBI
DACT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,797,372 - 52,810,945 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,668,208 - 54,681,776 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,639,921 - 43,653,473 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,168,739 - 52,182,015 (-)NCBIpanpan1.1PanPan1.1panPan2
DACT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,247,743 - 109,264,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,248,556 - 109,255,975 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,727,017 - 108,737,775 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,773,700 - 109,784,467 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,774,943 - 109,783,588 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,450,821 - 109,461,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,085,023 - 109,095,784 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,953,717 - 109,964,488 (+)NCBIUU_Cfam_GSD_1.0
Dact3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,889,423 - 18,896,201 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936664505,356 - 514,313 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DACT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,543,580 - 52,553,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,543,737 - 52,554,258 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,864,372 - 47,874,835 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DACT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,003,475 - 40,016,690 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,004,348 - 40,016,621 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,715,587 - 19,728,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSHGLT00000007488   ⟹   ENSHGLP00000007403
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248326,921,148 - 6,929,587 (+)Ensembl
RefSeq Acc Id: XM_004867092   ⟹   XP_004867149
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,921,000 - 6,930,391 (+)NCBI
RefSeq Acc Id: XM_021245929   ⟹   XP_021101588
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,920,993 - 6,930,391 (+)NCBI
RefSeq Acc Id: XM_021245930   ⟹   XP_021101589
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,920,994 - 6,930,391 (+)NCBI
RefSeq Acc Id: XM_021245931   ⟹   XP_021101590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,920,984 - 6,930,391 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004867149 (Get FASTA)   NCBI Sequence Viewer  
  XP_021101588 (Get FASTA)   NCBI Sequence Viewer  
  XP_021101589 (Get FASTA)   NCBI Sequence Viewer  
  XP_021101590 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021101590   ⟸   XM_021245931
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021101588   ⟸   XM_021245929
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021101589   ⟸   XM_021245930
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004867149   ⟸   XM_004867092
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000007403   ⟸   ENSHGLT00000007488


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005393 Ensembl
NCBI Gene Dact3 ENTREZGENE