Lhpp (phospholysine phosphohistidine inorganic pyrophosphate phosphatase) - Rat Genome Database

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Gene: Lhpp (phospholysine phosphohistidine inorganic pyrophosphate phosphatase) Heterocephalus glaber
Analyze
Symbol: Lhpp
Name: phospholysine phosphohistidine inorganic pyrophosphate phosphatase
RGD ID: 18900134
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN phosphate-containing compound metabolic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473722,498,276 - 22,621,179 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473722,433,400 - 22,620,586 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nuclear speck  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lhpp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473722,498,276 - 22,621,179 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473722,433,400 - 22,620,586 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LHPP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810124,461,823 - 124,614,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10124,461,823 - 124,617,888 (+)EnsemblGRCh38hg38GRCh38
GRCh3710126,150,392 - 126,302,710 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610126,140,402 - 126,292,699 (+)NCBINCBI36Build 36hg18NCBI36
Celera10119,922,531 - 120,076,588 (+)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10119,835,012 - 119,989,299 (+)NCBIHuRef
CHM1_110126,432,282 - 126,584,534 (+)NCBICHM1_1
T2T-CHM13v2.010125,340,028 - 125,495,193 (+)NCBIT2T-CHM13v2.0
Lhpp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397132,212,344 - 132,308,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7132,212,367 - 132,308,149 (+)EnsemblGRCm39 Ensembl
GRCm387132,610,615 - 132,706,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7132,610,638 - 132,706,420 (+)EnsemblGRCm38mm10GRCm38
MGSCv377139,802,326 - 139,898,102 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367132,448,986 - 132,544,762 (+)NCBIMGSCv36mm8
Celera7132,415,670 - 132,511,651 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map776.3NCBI
Lhpp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,833,516 - 196,924,687 (+)NCBIGRCr8
mRatBN7.21187,403,390 - 187,494,577 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1187,403,433 - 187,494,578 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1195,753,609 - 195,844,730 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01202,932,379 - 203,023,506 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01195,605,512 - 195,696,635 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01204,617,804 - 204,708,987 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1204,617,852 - 204,708,987 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,611,470 - 211,702,233 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41192,082,902 - 192,174,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11192,232,782 - 192,324,480 (+)NCBI
Celera1185,148,002 - 185,239,039 (+)NCBICelera
Cytogenetic Map1q41NCBI
Lhpp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554772,480,512 - 2,606,931 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554772,480,660 - 2,606,887 (+)NCBIChiLan1.0ChiLan1.0
LHPP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28136,307,474 - 136,460,818 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110136,312,833 - 136,465,237 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010121,020,252 - 121,169,792 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110125,288,085 - 125,438,338 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10125,288,124 - 125,438,214 (+)Ensemblpanpan1.1panPan2
LHPP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12833,828,088 - 33,954,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2833,816,035 - 33,954,356 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2833,890,466 - 34,016,883 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02834,384,943 - 34,512,355 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2834,373,150 - 34,512,353 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12833,941,616 - 34,068,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02833,933,827 - 34,060,784 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02834,184,936 - 34,312,308 (+)NCBIUU_Cfam_GSD_1.0
Lhpp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721312,693,887 - 12,789,338 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648612,771,896 - 12,868,542 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648612,771,977 - 12,867,411 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LHPP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14133,864,048 - 133,999,172 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114133,864,045 - 133,999,174 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214145,381,346 - 145,498,580 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LHPP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19117,122,951 - 117,273,044 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9117,123,021 - 117,272,348 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604878,440,531 - 78,624,928 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017652   ⟹   ENSHGLP00000017478
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473722,498,276 - 22,621,179 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000017653   ⟹   ENSHGLP00000017479
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473722,541,321 - 22,620,453 (-)Ensembl
RefSeq Acc Id: XM_004838752   ⟹   XP_004838809
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473722,498,966 - 22,620,582 (-)NCBI
RefSeq Acc Id: XM_004838754   ⟹   XP_004838811
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473722,498,966 - 22,620,578 (-)NCBI
RefSeq Acc Id: XM_021253302   ⟹   XP_021108961
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473722,560,690 - 22,620,586 (-)NCBI
RefSeq Acc Id: XM_021253303   ⟹   XP_021108962
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473722,433,400 - 22,620,586 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004838809 (Get FASTA)   NCBI Sequence Viewer  
  XP_004838811 (Get FASTA)   NCBI Sequence Viewer  
  XP_021108961 (Get FASTA)   NCBI Sequence Viewer  
  XP_021108962 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14541 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017478
  ENSHGLP00000017479
  ENSHGLP00100005918
GenBank Protein JAO00271 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021108962   ⟸   XM_021253303
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004838809   ⟸   XM_004838752
- Peptide Label: isoform X1
- UniProtKB: G5BZ30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004838811   ⟸   XM_004838754
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021108961   ⟸   XM_021253302
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000017478   ⟸   ENSHGLT00000017652
RefSeq Acc Id: ENSHGLP00000017479   ⟸   ENSHGLT00000017653


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012519 Ensembl, ENTREZGENE
  ENSHGLG00100004464 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017652 ENTREZGENE
  ENSHGLT00000017653 ENTREZGENE
  ENSHGLT00100006001 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1000 UniProtKB/TrEMBL
InterPro HAD-like_sf UniProtKB/TrEMBL
  HAD-SF_hydro_IIA UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  LHPP/HDHD2 UniProtKB/TrEMBL
KEGG Report hgl:101723766 UniProtKB/TrEMBL
NCBI Gene Lhpp ENTREZGENE
PANTHER 4-NITROPHENYLPHOSPHATASE-RELATED UniProtKB/TrEMBL
  PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE UniProtKB/TrEMBL
Pfam Hydrolase_6 UniProtKB/TrEMBL
  Hydrolase_like UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
UniProt G5BZ30 ENTREZGENE, UniProtKB/TrEMBL