Mgst2 (microsomal glutathione S-transferase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Mgst2 (microsomal glutathione S-transferase 2) Heterocephalus glaber
Analyze
Symbol: Mgst2
Name: microsomal glutathione S-transferase 2
RGD ID: 18899989
Description: ENCODES a protein that exhibits glutathione peroxidase activity (ortholog); glutathione transferase activity (ortholog); leukotriene-C4 synthase activity (ortholog); INVOLVED IN response to lipopolysaccharide (ortholog); response to organonitrogen compound (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477719,901,862 - 19,927,011 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477719,902,013 - 19,924,272 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mgst2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477719,901,862 - 19,927,011 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477719,902,013 - 19,924,272 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MGST2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384139,665,819 - 139,754,618 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4139,665,768 - 139,740,745 (+)EnsemblGRCh38hg38GRCh38
GRCh374140,586,973 - 140,661,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364140,806,372 - 140,844,857 (+)NCBINCBI36Build 36hg18NCBI36
Build 344140,944,526 - 140,983,009NCBI
Celera4137,919,740 - 137,958,224 (+)NCBICelera
Cytogenetic Map4q31.1NCBI
HuRef4136,315,768 - 136,391,008 (+)NCBIHuRef
CHM1_14140,564,114 - 140,639,227 (+)NCBICHM1_1
T2T-CHM13v2.04142,985,421 - 143,074,258 (+)NCBIT2T-CHM13v2.0
Mgst2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39351,544,179 - 51,590,096 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl351,567,781 - 51,590,098 (+)EnsemblGRCm39 Ensembl
GRCm38351,636,912 - 51,682,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl351,660,360 - 51,682,677 (+)EnsemblGRCm38mm10GRCm38
MGSCv37351,465,115 - 51,486,597 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36351,749,166 - 51,770,603 (+)NCBIMGSCv36mm8
Celera351,392,546 - 51,414,043 (+)NCBICelera
Cytogenetic Map3CNCBI
cM Map322.52NCBI
Mgst2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82137,821,787 - 137,866,664 (+)NCBIGRCr8
mRatBN7.22135,679,524 - 135,715,828 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2135,693,557 - 135,715,828 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2142,269,446 - 142,291,715 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02140,381,704 - 140,403,975 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02135,013,740 - 135,035,919 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02140,708,396 - 140,727,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2140,708,397 - 140,727,281 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02160,180,714 - 160,202,851 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42140,546,939 - 140,568,616 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12140,497,066 - 140,518,579 (+)NCBI
Celera2130,188,760 - 130,210,429 (+)NCBICelera
Cytogenetic Map2q26NCBI
Mgst2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554284,014,810 - 4,037,901 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554284,006,054 - 4,049,497 (-)NCBIChiLan1.0ChiLan1.0
MGST2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23137,540,753 - 137,605,499 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14137,933,175 - 137,997,878 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04132,031,087 - 132,106,864 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14143,338,016 - 143,412,966 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4143,338,016 - 143,412,966 (+)Ensemblpanpan1.1panPan2
MGST2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,067,062 - 3,070,579 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha193,314,243 - 3,335,238 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0193,136,172 - 3,157,176 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,122,591 - 3,157,324 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,069,101 - 3,090,099 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,429,861 - 3,450,892 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,793,259 - 3,814,268 (-)NCBIUU_Cfam_GSD_1.0
Mgst2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530150,548,928 - 50,578,317 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365357,995,248 - 8,015,463 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365357,995,185 - 8,015,463 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGST2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl887,327,425 - 87,390,520 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1887,318,180 - 87,394,563 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MGST2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1786,629,691 - 86,666,912 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl786,629,642 - 86,666,857 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603766,152,315 - 66,189,340 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000014405   ⟹   ENSHGLP00000014261
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477719,901,862 - 19,927,011 (+)Ensembl
RefSeq Acc Id: XM_004854992   ⟹   XP_004855049
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477719,902,013 - 19,924,272 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855049 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014261
  ENSHGLP00000045891
  ENSHGLP00100047035
GenBank Protein JAN96753 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004855049   ⟸   XM_004854992
- UniProtKB: A0A0P6J319 (UniProtKB/TrEMBL),   G5BXF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014261   ⟸   ENSHGLT00000014405


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010191 Ensembl, ENTREZGENE
  ENSHGLG00000040336 UniProtKB/TrEMBL
  ENSHGLG00100041049 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014405 ENTREZGENE
  ENSHGLT00000059091 UniProtKB/TrEMBL
  ENSHGLT00100074567 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.550 UniProtKB/TrEMBL
InterPro 5_LipOase_AP UniProtKB/TrEMBL
  FLAP/GST2/LTC4S_CS UniProtKB/TrEMBL
  MAPEG-like_dom_sf UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/TrEMBL
KEGG Report hgl:101716174 UniProtKB/TrEMBL
NCBI Gene Mgst2 ENTREZGENE
PANTHER MICROSOMAL GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
  MICROSOMAL GLUTATHIONE S-TRANSFERASE 2 UniProtKB/TrEMBL
Pfam MAPEG UniProtKB/TrEMBL
PRINTS 5LPOXGNASEAP UniProtKB/TrEMBL
PROSITE FLAP_GST2_LTC4S UniProtKB/TrEMBL
Superfamily-SCOP SSF161084 UniProtKB/TrEMBL
UniProt A0A0P6J319 ENTREZGENE, UniProtKB/TrEMBL
  G5BXF3 ENTREZGENE, UniProtKB/TrEMBL