TAS2R4 (taste 2 receptor member 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TAS2R4 (taste 2 receptor member 4) Chlorocebus sabaeus
Analyze
Symbol: TAS2R4
Name: taste 2 receptor member 4
RGD ID: 18795017
Description: ENCODES a protein that exhibits bitter taste receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN respiratory gaseous exchange by respiratory system (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hereditary Pancreatitis (ortholog); RASopathy (ortholog); FOUND IN ciliary membrane (inferred); cilium (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: taste receptor type 2 member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121110,522,405 - 110,526,497 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21110,524,134 - 110,525,030 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660727,202,226 - 7,203,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TAS2R4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121110,522,405 - 110,526,497 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21110,524,134 - 110,525,030 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660727,202,226 - 7,203,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TAS2R4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387141,776,674 - 141,781,691 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7141,776,674 - 141,781,691 (+)EnsemblGRCh38hg38GRCh38
GRCh377141,476,474 - 141,481,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367141,124,758 - 141,125,657 (+)NCBINCBI36Build 36hg18NCBI36
Build 347140,931,472 - 140,932,372NCBI
Celera7136,199,919 - 136,200,818 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7135,774,951 - 135,775,850 (+)NCBIHuRef
CHM1_17141,412,637 - 141,413,536 (+)NCBICHM1_1
T2T-CHM13v2.07143,092,504 - 143,097,521 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27140,816,001 - 140,816,900 (+)NCBI
Tas2r108
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39640,470,526 - 40,471,419 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl640,470,463 - 40,471,475 (+)EnsemblGRCm39 Ensembl
GRCm38640,493,592 - 40,494,485 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl640,493,529 - 40,494,541 (+)EnsemblGRCm38mm10GRCm38
MGSCv37640,443,591 - 40,444,484 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36640,423,199 - 40,424,092 (+)NCBIMGSCv36mm8
Celera640,481,006 - 40,481,899 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.82NCBI
Tas2r108
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8470,254,367 - 70,255,281 (+)NCBIGRCr8
mRatBN7.2469,287,667 - 69,288,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl469,287,667 - 69,288,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx474,215,943 - 74,216,857 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0470,137,097 - 70,138,011 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0468,548,582 - 68,549,496 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0468,656,928 - 68,657,842 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl468,656,928 - 68,657,842 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04133,442,680 - 133,443,594 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4468,048,215 - 68,049,129 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera464,290,689 - 64,291,603 (+)NCBICelera
Cytogenetic Map4q23NCBI
Tas2r4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554941,790,395 - 1,791,294 (-)NCBIChiLan1.0ChiLan1.0
TAS2R4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26178,559,485 - 178,569,624 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1730,568,935 - 30,579,865 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07133,707,669 - 133,712,521 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17146,178,828 - 146,181,638 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7146,179,311 - 146,180,210 (+)Ensemblpanpan1.1panPan2
TAS2R4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1167,424,277 - 7,425,302 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl167,424,403 - 7,425,492 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha168,269,058 - 8,269,957 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0167,345,992 - 7,346,891 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl167,345,992 - 7,346,891 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1167,299,289 - 7,300,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0167,141,662 - 7,142,561 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0167,209,422 - 7,210,321 (-)NCBIUU_Cfam_GSD_1.0
Tas2r4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511813,577,619 - 13,580,155 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365925,639,761 - 5,642,187 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAS2R4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl188,134,381 - 8,135,271 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1188,133,298 - 8,136,564 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Tas2r4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476521,784,123 - 21,785,022 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476521,780,469 - 21,786,230 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system nervous system
High
Medium
Low 11
Below cutoff 7 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007983194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000019241   ⟹   ENSCSAP00000018661
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl21110,524,134 - 110,525,030 (+)Ensembl
RefSeq Acc Id: XM_007983194   ⟹   XP_007981385
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.121110,522,405 - 110,526,497 (+)NCBI
Vero_WHO_p1.0NW_0236660727,202,226 - 7,203,992 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007981385 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018661.1
Reference Protein Sequences
RefSeq Acc Id: XP_007981385   ⟸   XM_007983194
- UniProtKB: A0A0D9SCS2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000018661   ⟸   ENSCSAT00000019241


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019151 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019241.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro T2R UniProtKB/TrEMBL
  TAS2R4 UniProtKB/TrEMBL
KEGG Report csab:103227039 UniProtKB/TrEMBL
NCBI Gene TAS2R4 ENTREZGENE
PANTHER PTHR11394:SF55 UniProtKB/TrEMBL
  TASTE RECEPTOR TYPE 2 UniProtKB/TrEMBL
Pfam TAS2R UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9SCS2 ENTREZGENE, UniProtKB/TrEMBL