SMPD1 (sphingomyelin phosphodiesterase 1)

Gene: SMPD1 (sphingomyelin phosphodiesterase 1) Chlorocebus sabaeus

Analyze

Symbol:

SMPD1

Name:

sphingomyelin phosphodiesterase 1

RGD ID:

18791332

Description:

ENCODES a protein that exhibits acid sphingomyelin phosphodiesterase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); metal ion binding (inferred); INVOLVED IN ceramide biosynthetic process (ortholog); ceramide metabolic process (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; Trail mediated signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); Gaucher's disease (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); lamellar body (ortholog); lysosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sphingomyelin phosphodiesterase

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	58,431,677 - 58,436,233 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	58,432,068 - 58,436,236 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	156,257,313 - 156,261,990 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Diabetes Mellitus (ISO)

Gaucher's disease (ISO)

genetic disease (ISO)

intellectual disability (ISO)

kidney disease (ISO)

Neoplasm Invasiveness (ISO)

neuronal ceroid lipofuscinosis (ISO)

neuronal ceroid lipofuscinosis 6A (ISO)

Niemann-Pick disease (ISO)

Niemann-Pick disease type A (ISO)

Niemann-Pick disease type B (ISO)

Niemann-Pick disease type C1 (ISO)

Niemann-Pick Disease, Intermediate, Protracted Neurovisceral (ISO)

Wilson disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to calcium ion (IEA)

cellular response to UV (IEA)

ceramide biosynthetic process (IEA,ISO)

ceramide metabolic process (IEA,ISO)

cholesterol metabolic process (IEA,ISO)

plasma membrane repair (IEA)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of endocytosis (IEA)

positive regulation of protein dephosphorylation (IEA)

positive regulation of viral entry into host cell (IEA)

response to cocaine (ISO)

response to interleukin-1 (IEA)

response to ionizing radiation (IEA)

response to tumor necrosis factor (IEA)

response to type I interferon (IEA)

response to virus (IEA)

response to xenobiotic stimulus (ISO)

sphingomyelin catabolic process (IEA,ISO)

symbiont entry into host cell (IEA,ISO)

termination of signal transduction (IEA)

wound healing (IEA)

Cellular Component

endolysosome (IEA)

endosome (IEA)

extracellular region (IEA)

extracellular space (IEA,ISO)

lamellar body (ISO)

lysosome (IEA,ISO)

plasma membrane (IEA)

Molecular Function

acid sphingomyelin phosphodiesterase activity (IEA)

hydrolase activity, acting on glycosyl bonds (IEA)

metal ion binding (IEA)

protein binding (ISO)

sphingomyelin phosphodiesterase activity (IEA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ceramide signaling pathway (ISO)

FasL mediated signaling pathway (ISO)

Trail mediated signaling pathway (ISO)

tumor necrosis factor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SMPD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	58,431,677 - 58,436,233 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	58,432,068 - 58,436,236 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	156,257,313 - 156,261,990 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SMPD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	6,390,474 - 6,394,996 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	6,390,440 - 6,394,998 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	6,411,704 - 6,416,226 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	6,368,231 - 6,372,802 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	6,368,230 - 6,372,801	NCBI
Celera	11	6,530,711 - 6,535,296 (+)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	6,070,739 - 6,075,337 (+)	NCBI		HuRef
CHM1_1	11	6,410,778 - 6,415,363 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	6,448,931 - 6,453,455 (+)	NCBI		T2T-CHM13v2.0

Smpd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	105,203,567 - 105,207,596 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	105,203,567 - 105,207,596 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	105,554,360 - 105,558,389 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	105,554,360 - 105,558,389 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	112,702,874 - 112,706,903 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	105,428,236 - 105,432,203 (+)	NCBI		MGSCv36	mm8
Celera	7	105,825,502 - 105,829,531 (+)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	55.9	NCBI

Smpd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	169,304,772 - 169,308,615 (+)	NCBI		GRCr8
mRatBN7.2	1	159,892,946 - 159,896,789 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	159,892,859 - 159,896,794 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	167,915,425 - 167,919,268 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	175,101,419 - 175,105,262 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	168,003,243 - 168,007,086 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	170,383,682 - 170,387,525 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	170,383,682 - 170,387,524 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	177,389,588 - 177,393,431 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	163,278,970 - 163,282,813 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	157,825,620 - 157,829,463 (+)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

Smpd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	22,117,930 - 22,121,744 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	22,117,929 - 22,121,744 (+)	NCBI	ChiLan1.0	ChiLan1.0

SMPD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	8,826,802 - 8,831,484 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	8,790,673 - 8,795,342 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	6,521,812 - 6,526,349 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	6,205,278 - 6,209,950 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

SMPD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	29,714,418 - 29,719,035 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	29,714,557 - 29,719,033 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	29,416,446 - 29,421,072 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	30,540,703 - 30,545,329 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	30,540,764 - 30,545,592 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	29,861,608 - 29,866,232 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	30,027,386 - 30,032,012 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	30,222,733 - 30,227,359 (+)	NCBI		UU_Cfam_GSD_1.0

Smpd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	56,222,931 - 56,227,200 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936842	447,991 - 452,630 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936842	448,315 - 452,557 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMPD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	3,324,442 - 3,328,457 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	3,324,091 - 3,328,493 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	3,961,624 - 3,964,422 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Smpd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624817	7,909,468 - 7,913,417 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624817	7,909,777 - 7,913,419 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36	2	42
Low		18	18
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008008816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008008821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008008831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037999796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000002348 ⟹ ENSCSAP00000000661

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	1	58,432,068 - 58,436,236 (-)	Ensembl

RefSeq Acc Id:

XM_008008816 ⟹ XP_008007007

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	58,431,679 - 58,436,231 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	156,257,313 - 156,261,990 (-)	NCBI

Sequence:

show sequence

GGAGATCAGAGGAAGAGGAAGGGGCGGAGCTGCTTTGCGGCCGGCCGCGAAGCAGTCAGCCGGC
TACAGAGAAGGGTAATCGGGTGTCCTCAGCGCCGCCTGGGGCCCTGAGGGCCAGCTAGGGCCCA
GGCCGGTGGGGACGGGACAAACGAACTAGCCCCGTGTAGGAAGCCTGACAATGCCCCGCTACGG
AGCATCACCGCGCCAGAGTCGCCCCAGGTCCGGCCGGGAGCAGGGACAAGACAGGACCTTCGGA
GCCCCCCCACTCCTTTGGATGGGCCTGGTACTGGTGCTGGCGCTGGCTCTGGCTCTGTCTGACT
CTCTGGTTCTCTGGCCGGCAGAGGCTCATCCTCTTCCTCCCCAAGGCCATCCTGCCAGGTTACA
TCGCATAGCGCCCCGTCTCCGAGATGTCTTTGGGTGGGGGAACCTCACCTGCCCAGTCTGCAAA
GGTCTATTCACCGCCATCAACCTTGGGCTGAAGAAGGAACCCAATGTGGCTCGCGTGGGTTCCA
TGGCCATCAAGCTGTGCAATCTGCTGAAGATAGCACCACCTGCCGTGTGCCAATCCATTGTCCA
GCTCTTTGAGGATGACATGGTGGAGGTGTGGAGACGCTCAGTGCTGAGCCCATCTGAGGCCTGC
GGCCTGCTCCTGGGCTCCACCTGTGGGCACTGGGACATTTTCTCATCTTGGAACATCTCTTTGC
CTACTGTGCCGAAGCCGCCCCCCAAACCCCCTAGCCCCCCAGCCCCAGGTGCCCCTGTCAGCCG
CGTCCTCTTCCTCACTGACCTGCACTGGGATCATGACTACCTGGAGGGCATGGACCCTGACTGT
GCCGACCCACTGTGTTGCCGCCAGGGTTCTGGCCTGCCGCCGGCATCCCGGCCAGGTGCTGGAT
ACTGGGGGGAATACAGCAAGTGTGACCTGCCCCTGAGGACCCTGGAAAGCCTGTTGAGTGGGCT
GGGCCCAGCCGGCCCTTTTGATATGGTATACTGGACAGGAGACATCCCTGCACATGATGTCTGG
CACCAGACTCGTCAGGACCAGCTGCGGGCCCTGACCACTGTCACAGCACTTGTGAGGAAGTTCC
TGGGGCCAGTGCCAGTGTACCCTGCTGTGGGCAACCACGAGAGCACACCCGTCAATAGCTTCCC
TCCCCCCTTCATTGAGGGCAACCACTCCTCCCGCTGGCTCTACGAAGCGATGGCCAAGGCTTGG
GAGCCCTGGCTGCCTGCTGAAGCCCTGCGCACCCTCAGGTACTTATCATCCATGGAAACCCAGG
AAGGGAAAAAAAGAATTGGGGGGTTCTATGCTCTTTCCCCATACCCCGGTCTCCGCCTCATCTC
TCTCAATATGAATTTTTGTTCCCGTGAGAACTTCTGGCTCTTGATCAACTCCACGGATCCTGCA
GGACAGCTCCAGTGGCTGGTGGGGGAGCTCCAGGCTGCTGAGGATCGAGGAGACAAAGTGCATA
TAATTGGCCACATTCCCCCAGGGCACTGTCTGAAGAGCTGGAGCTGGAATTATTACCGAATTGT
AGCCAGGTATGAGAACACCCTGGCTGCTCAGTTCTTTGGCCACACTCATGTGGATGAATTTGAG
GTCTTCTATGATGAAGAGACTCTGAGCCGGCCGCTGGCTGTAGCCTTCCTGGCACCCAGTGCAA
CTACCTACATCGGCCTTAATCCTGGTTACCGTGTGTACCAAATAGATGGAAACTACTCCGGGAG
CTCTCACGTAGTCTTGGACCATGAGACTTACATCCTGAATCTGACCCAGGCGAACACACCGGGA
GCTATACCGCACTGGCAGCTTCTCTACAGGGCTCGAGAAACCTATGGGCTGCCCAACACACTGC
CTACCGCTTGGCACAACTTGGTATATCGCATGCGGGGCGACATGCAACTCTTCCAGACCTTCTG
GTTTCTCTACCATAAGGGCCACCCGCCCTCAGAGCCCTGTGGCACGCCCTGCCGTCTGGCTACT
CTTTGTGCCCAGCTCTCTGCCCGTGCTGACAGCCCTGCTCTGTGCCGCCACCTGATGCTAGATG
GGAGCCTCCCAGAGGCCCACAGCCTGTGGCCAAGGCCACTGTTTTGCTAGGGCCCCAGGGCCCA
CATTTGGAAAAGTTCTTGATGTAGGAAAGGATGAAAAAGCCCAAATGCTGCTGTGGTTCAACCA
AGCAAGGTCATCCAGTGGAAGAACCAGTCCCTGGGCCCCAAGGATGCCGGGGAAACAGGACCTT
ATCCTTTCTTGGAGCTCGTTTAGCTGGATATGGGAGGGGGTTTGGCTGCCTGTGCCCAGGAGCT
AAACTGCCTTGAGGCTGCTGTCCTTTCACAGCCATGGAATAGAGGCCTAAGTTGACACCGCCCT
GGGCAGACAAGACAGGAGCTGTTGCCCCAGGCCTGTGCTGCCCAGCCAGGAACCCTGTACTGCT
GCTGCGACCTGATCCCGCCAGTCTGTTAAAATAAAGATAAGAGACTTGCACTCTA

hide sequence

RefSeq Acc Id:

XM_008008821 ⟹ XP_008007012

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	58,431,677 - 58,436,233 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	156,257,313 - 156,261,990 (-)	NCBI

Sequence:

show sequence

TTGGAGATCAGAGGAAGAGGAAGGGGCGGAGCTGCTTTGCGGCCGGCCGCGAAGCAGTCAGCCG
GCTACAGAGAAGGGTAATCGGGTGTCCTCAGCGCCGCCTGGGGCCCTGAGGGCCAGCTAGGGCC
CAGGCCGGTGGGGACGGGACAAACGAACTAGCCCCGTGTAGGAAGCCTGACAATGCCCCGCTAC
GGAGCATCACCGCGCCAGAGTCGCCCCAGGTCCGGCCGGGAGCAGGGACAAGACAGGACCTTCG
GAGCCCCCCCACTCCTTTGGATGGGCCTGGTACTGGTGCTGGCGCTGGCTCTGGCTCTGTCTGA
CTCTCTGGTTCTCTGGCCGGCAGAGGCTCATCCTCTTCCTCCCCAAGGCCATCCTGCCAGGTTA
CATCGCATAGCGCCCCGTCTCCGAGATGTCTTTGGGTGGGGGAACCTCACCTGCCCAGTCTGCA
AAGGTCTATTCACCGCCATCAACCTTGGGCTGAAGAAGGAACCCAATGTGGCTCGCGTGGGTTC
CATGGCCATCAAGCTGTGCAATCTGCTGAAGATAGCACCACCTGCCGTGTGCCAATCCATTGTC
CAGCTCTTTGAGGATGACATGGTGGAGGTGTGGAGACGCTCAGTGCTGAGCCCATCTGAGGCCT
GCGGCCTGCTCCTGGGCTCCACCTGTGGGCACTGGGACATTTTCTCATCTTGGAACATCTCTTT
GCCTACTGTGCCGAAGCCGCCCCCCAAACCCCCTAGCCCCCCAGCCCCAGGTGCCCCTGTCAGC
CGCGTCCTCTTCCTCACTGACCTGCACTGGGATCATGACTACCTGGAGGGCATGGACCCTGACT
GTGCCGACCCACTGTGTTGCCGCCAGGGTTCTGGCCTGCCGCCGGCATCCCGGCCAGGTGCTGG
ATACTGGGGGGAATACAGCAAGTGTGACCTGCCCCTGAGGACCCTGGAAAGCCTGTTGAGTGGG
CTGGGCCCAGCCGGCCCTTTTGATATGGTATACTGGACAGGAGACATCCCTGCACATGATGTCT
GGCACCAGACTCGTCAGGACCAGCTGCGGGCCCTGACCACTGTCACAGCACTTGTGAGGAAGTT
CCTGGGGCCAGTGCCAGTGTACCCTGCTGTGGGCAACCACGAGAGCACACCCGTCAATAGCTTC
CCTCCCCCCTTCATTGAGGGCAACCACTCCTCCCGCTGGCTCTACGAAGCGATGGCCAAGGCTT
GGGAGCCCTGGCTGCCTGCTGAAGCCCTGCGCACCCTCAGAATTGGGGGGTTCTATGCTCTTTC
CCCATACCCCGGTCTCCGCCTCATCTCTCTCAATATGAATTTTTGTTCCCGTGAGAACTTCTGG
CTCTTGATCAACTCCACGGATCCTGCAGGACAGCTCCAGTGGCTGGTGGGGGAGCTCCAGGCTG
CTGAGGATCGAGGAGACAAAGTGCATATAATTGGCCACATTCCCCCAGGGCACTGTCTGAAGAG
CTGGAGCTGGAATTATTACCGAATTGTAGCCAGGTATGAGAACACCCTGGCTGCTCAGTTCTTT
GGCCACACTCATGTGGATGAATTTGAGGTCTTCTATGATGAAGAGACTCTGAGCCGGCCGCTGG
CTGTAGCCTTCCTGGCACCCAGTGCAACTACCTACATCGGCCTTAATCCTGGTTACCGTGTGTA
CCAAATAGATGGAAACTACTCCGGGAGCTCTCACGTAGTCTTGGACCATGAGACTTACATCCTG
AATCTGACCCAGGCGAACACACCGGGAGCTATACCGCACTGGCAGCTTCTCTACAGGGCTCGAG
AAACCTATGGGCTGCCCAACACACTGCCTACCGCTTGGCACAACTTGGTATATCGCATGCGGGG
CGACATGCAACTCTTCCAGACCTTCTGGTTTCTCTACCATAAGGGCCACCCGCCCTCAGAGCCC
TGTGGCACGCCCTGCCGTCTGGCTACTCTTTGTGCCCAGCTCTCTGCCCGTGCTGACAGCCCTG
CTCTGTGCCGCCACCTGATGCTAGATGGGAGCCTCCCAGAGGCCCACAGCCTGTGGCCAAGGCC
ACTGTTTTGCTAGGGCCCCAGGGCCCACATTTGGAAAAGTTCTTGATGTAGGAAAGGATGAAAA
AGCCCAAATGCTGCTGTGGTTCAACCAAGCAAGGTCATCCAGTGGAAGAACCAGTCCCTGGGCC
CCAAGGATGCCGGGGAAACAGGACCTTATCCTTTCTTGGAGCTCGTTTAGCTGGATATGGGAGG
GGGTTTGGCTGCCTGTGCCCAGGAGCTAAACTGCCTTGAGGCTGCTGTCCTTTCACAGCCATGG
AATAGAGGCCTAAGTTGACACCGCCCTGGGCAGACAAGACAGGAGCTGTTGCCCCAGGCCTGTG
CTGCCCAGCCAGGAACCCTGTACTGCTGCTGCGACCTGATCCCGCCAGTCTGTTAAAATAAAGA
TAAGAGACTTGCACTCTAGA

hide sequence

RefSeq Acc Id:

XM_037999796 ⟹ XP_037855724

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666038	156,257,313 - 156,261,990 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008007007	(Get FASTA)	NCBI Sequence Viewer
	XP_008007012	(Get FASTA)	NCBI Sequence Viewer
	XP_037855724	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000661.1

RefSeq Acc Id:	XP_008007012 ⟸ XM_008008821
- Peptide Label:	isoform X3
- UniProtKB:	A0A0D9QWC2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_008007007 ⟸ XM_008008816
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QWC2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000000661 ⟸ ENSCSAT00000002348

RefSeq Acc Id:	XP_037855724 ⟸ XM_037999796
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9QWC2 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004314	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002348.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.21.10	UniProtKB/TrEMBL
InterPro	ASM_C	UniProtKB/TrEMBL
	ASMase/PPN1_MPP	UniProtKB/TrEMBL
	Calcineurin-like_PHP_ApaH	UniProtKB/TrEMBL
	Metallo-depent_PP-like	UniProtKB/TrEMBL
	Saposin-like	UniProtKB/TrEMBL
	SaposinB_dom	UniProtKB/TrEMBL
	Sphingomy_PDE	UniProtKB/TrEMBL
NCBI Gene	SMPD1	ENTREZGENE
PANTHER	SPHINGOMYELIN PHOSPHODIESTERASE	UniProtKB/TrEMBL
	SPHINGOMYELIN PHOSPHODIESTERASE	UniProtKB/TrEMBL
Pfam	ASMase_C	UniProtKB/TrEMBL
	Metallophos	UniProtKB/TrEMBL
PIRSF	Sphingomy_PDE	UniProtKB/TrEMBL
PROSITE	SAP_B	UniProtKB/TrEMBL
SMART	SapB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47862	UniProtKB/TrEMBL
	SSF56300	UniProtKB/TrEMBL
UniProt	A0A0D9QWC2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)