PIGU (phosphatidylinositol glycan anchor biosynthesis class U) - Rat Genome Database

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Gene: PIGU (phosphatidylinositol glycan anchor biosynthesis class U) Chlorocebus sabaeus
Analyze
Symbol: PIGU
Name: phosphatidylinositol glycan anchor biosynthesis class U
RGD ID: 18786149
Description: ENCODES a protein that exhibits GPI anchor binding (ortholog); INVOLVED IN regulation of receptor signaling pathway via JAK-STAT (ortholog); ASSOCIATED WITH genetic disease (ortholog); Glycosylphosphatidylinositol Biosynthesis Defect 21 (ortholog); long QT syndrome (ortholog); FOUND IN GPI-anchor transamidase complex (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol glycan anchor biosynthesis class U protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1238,859,142 - 38,965,926 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl238,859,474 - 38,965,731 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605087,863,868 - 87,971,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PIGU
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1238,859,142 - 38,965,926 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl238,859,474 - 38,965,731 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605087,863,868 - 87,971,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PIGU
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382034,560,542 - 34,677,092 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2034,560,542 - 34,698,790 (-)EnsemblGRCh38hg38GRCh38
GRCh372033,148,346 - 33,264,896 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362032,612,007 - 32,728,750 (-)NCBINCBI36Build 36hg18NCBI36
Build 342032,612,006 - 32,728,750NCBI
Celera2029,897,474 - 30,014,189 (-)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2029,928,895 - 30,044,277 (-)NCBIHuRef
CHM1_12033,049,160 - 33,166,522 (-)NCBICHM1_1
T2T-CHM13v2.02036,283,696 - 36,397,781 (-)NCBIT2T-CHM13v2.0
Pigu
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,120,163 - 155,199,344 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2155,120,163 - 155,199,350 (-)EnsemblGRCm39 Ensembl
GRCm382155,278,243 - 155,357,424 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,278,243 - 155,357,430 (-)EnsemblGRCm38mm10GRCm38
MGSCv372155,103,988 - 155,183,160 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362154,969,693 - 155,048,865 (-)NCBIMGSCv36mm8
Celera2161,210,808 - 161,289,950 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.18NCBI
Pigu
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,245,011 - 164,341,444 (-)NCBIGRCr8
mRatBN7.23143,784,831 - 143,881,268 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3143,784,832 - 143,880,807 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3147,650,902 - 147,724,039 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,268,183 - 156,341,312 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,007,720 - 154,080,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03150,803,096 - 150,885,597 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3150,803,097 - 150,885,616 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,171,341 - 157,253,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,760,693 - 145,841,916 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13145,666,315 - 145,747,538 (-)NCBI
Celera3142,512,108 - 142,584,503 (-)NCBICelera
Cytogenetic Map3q41NCBI
Pigu
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,685,060 - 26,775,416 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,685,060 - 26,774,261 (+)NCBIChiLan1.0ChiLan1.0
PIGU
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,293,599 - 40,408,274 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,286,701 - 40,401,376 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02030,889,183 - 31,004,166 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,020,608 - 32,133,493 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,020,608 - 32,133,493 (-)Ensemblpanpan1.1panPan2
PIGU
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12423,674,133 - 23,768,119 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2423,674,137 - 23,768,073 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,319,722 - 23,413,720 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,364,628 - 24,458,705 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,364,632 - 24,458,661 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12423,651,987 - 23,746,793 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02423,747,087 - 23,841,930 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,186,009 - 24,280,792 (-)NCBIUU_Cfam_GSD_1.0
Pigu
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640172,645,001 - 172,736,404 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365616,013,145 - 6,107,667 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365616,013,145 - 6,104,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIGU
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1737,942,707 - 38,081,392 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11737,959,703 - 38,081,110 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21743,158,041 - 43,276,737 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pigu
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248424,692,741 - 4,800,825 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248424,692,831 - 4,800,342 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 6 44
Low 14 16
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000010094   ⟹   ENSCSAP00000008193
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl238,859,474 - 38,965,731 (-)Ensembl
RefSeq Acc Id: XM_008021426   ⟹   XP_008019617
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1238,859,142 - 38,965,926 (-)NCBI
Vero_WHO_p1.0NW_02366605087,863,868 - 87,971,667 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021436   ⟹   XP_008019627
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1238,859,142 - 38,965,787 (-)NCBI
Vero_WHO_p1.0NW_02366605087,863,922 - 87,971,667 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021444   ⟹   XP_008019635
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1238,859,142 - 38,965,779 (-)NCBI
Vero_WHO_p1.0NW_02366605087,863,922 - 87,971,667 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008019617 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019627 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019635 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008193
  ENSCSAP00000008193.1
Reference Protein Sequences
RefSeq Acc Id: XP_008019617   ⟸   XM_008021426
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019627   ⟸   XM_008021436
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008019635   ⟸   XM_008021444
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000008193   ⟸   ENSCSAT00000010094


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012058 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010094.1 UniProtKB/TrEMBL
InterPro PIG-U UniProtKB/TrEMBL
KEGG Report csab:103248784 UniProtKB/TrEMBL
NCBI Gene PIGU ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN UniProtKB/TrEMBL
  PTHR13121 UniProtKB/TrEMBL
Pfam PIG-U UniProtKB/TrEMBL
UniProt A0A0D9RHV4 ENTREZGENE, UniProtKB/TrEMBL