RAB40C (RAB40C, member RAS oncogene family) - Rat Genome Database

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Gene: RAB40C (RAB40C, member RAS oncogene family) Chlorocebus sabaeus
Analyze
Symbol: RAB40C
Name: RAB40C, member RAS oncogene family
RGD ID: 18785915
Description: ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); INVOLVED IN intracellular signal transduction (inferred); protein localization to plasma membrane (inferred); protein ubiquitination (inferred); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); idiopathic generalized epilepsy (ortholog); FOUND IN Golgi apparatus (ortholog); lipid droplet (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-40C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15511,517 - 545,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5511,660 - 544,225 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,589,408 - 30,648,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAB40C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15511,517 - 545,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5511,660 - 544,225 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,589,408 - 30,648,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAB40C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816589,357 - 629,268 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16589,357 - 629,272 (+)EnsemblGRCh38hg38GRCh38
GRCh3716639,357 - 679,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616580,177 - 619,273 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416580,179 - 619,272NCBI
Celera16840,134 - 879,407 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16561,196 - 600,572 (+)NCBIHuRef
CHM1_116639,212 - 679,111 (+)NCBICHM1_1
T2T-CHM13v2.016593,278 - 633,302 (+)NCBIT2T-CHM13v2.0
Rab40c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,101,088 - 26,138,688 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,101,088 - 26,138,701 (-)EnsemblGRCm39 Ensembl
GRCm381725,882,114 - 25,919,714 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,882,114 - 25,919,727 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,019,059 - 26,056,659 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,609,714 - 25,647,302 (-)NCBIMGSCv36mm8
Celera1726,415,170 - 26,452,734 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.97NCBI
Rab40c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,405,436 - 15,440,659 (-)NCBIGRCr8
mRatBN7.21014,900,926 - 14,936,153 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,900,929 - 14,936,557 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,641,467 - 19,675,115 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,130,345 - 19,163,990 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,630,680 - 14,664,091 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,247,913 - 15,283,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,247,914 - 15,282,951 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,060,856 - 15,096,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,147,861 - 15,181,653 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,147,860 - 15,181,653 (-)NCBI
Celera1014,571,341 - 14,604,815 (-)NCBICelera
Cytogenetic Map10q12NCBI
Rab40c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,577,843 - 16,614,639 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,577,843 - 16,614,132 (-)NCBIChiLan1.0ChiLan1.0
RAB40C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218831,336 - 869,340 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,615,216 - 4,653,206 (+)NCBINHGRI_mPanPan1
PanPan1.116600,153 - 642,365 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16606,023 - 640,714 (+)Ensemblpanpan1.1panPan2
RAB40C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,937,858 - 39,968,042 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,939,004 - 39,945,765 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,201,465 - 41,228,245 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,280,019 - 40,306,809 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,280,023 - 40,307,845 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,968,542 - 39,995,318 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,928,729 - 39,955,488 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,407,910 - 40,434,695 (-)NCBIUU_Cfam_GSD_1.0
Rab40c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,277,803 - 112,311,387 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501373,859 - 409,267 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501375,663 - 409,243 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB40C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,140,561 - 41,160,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,140,557 - 41,160,101 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,328,868 - 41,330,727 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rab40c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,403,374 - 1,442,382 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,402,655 - 1,441,509 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 55
Low 1 20 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000010768   ⟹   ENSCSAP00000008858
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl5511,660 - 544,225 (+)Ensembl
RefSeq Acc Id: XM_007980258   ⟹   XP_007978449
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.15511,517 - 545,868 (+)NCBI
Vero_WHO_p1.0NW_02366606830,589,408 - 30,648,400 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007978449 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008858
  ENSCSAP00000008858.1
Reference Protein Sequences
RefSeq Acc Id: XP_007978449   ⟸   XM_007980258
- UniProtKB: A0A0D9RJR9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000008858   ⟸   ENSCSAT00000010768


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012720 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010768.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
  SOCS_box-like_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103225477 UniProtKB/TrEMBL
NCBI Gene RAB40C ENTREZGENE
PANTHER LD44762P UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-40C UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9RJR9 ENTREZGENE, UniProtKB/TrEMBL