SLC46A1 (solute carrier family 46 member 1)

Gene: SLC46A1 (solute carrier family 46 member 1) Chlorocebus sabaeus

Analyze

Symbol:

SLC46A1

Name:

solute carrier family 46 member 1

RGD ID:

18784887

Description:

ENCODES a protein that exhibits heme transmembrane transporter activity (ortholog); INVOLVED IN folate import across plasma membrane (inferred); folate transmembrane transport (inferred); folic acid transport (inferred); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; folate metabolic pathway; ASSOCIATED WITH anemia (ortholog); chronic kidney disease (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN basolateral plasma membrane (ortholog); brush border membrane (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

proton-coupled folate transporter

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	22,164,661 - 22,173,376 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	22,166,318 - 22,173,240 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	7,954,712 - 7,965,674 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

anemia (ISO)

chronic kidney disease (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

hereditary folate malabsorption (ISO)

hyperhomocysteinemia (ISO)

intellectual disability (ISO)

Malabsorption Syndromes (ISO)

pancytopenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

folate import across plasma membrane (IEA)

folate transmembrane transport (IEA)

folic acid transport (IEA)

heme transport (IEA)

methotrexate transport (IEA)

proton transmembrane transport (IEA)

transmembrane transport (IEA)

Cellular Component

apical plasma membrane (IEA)

basolateral plasma membrane (IEA,ISO)

brush border membrane (ISO)

cytoplasm (IEA)

endosome (IEA)

endosome membrane (IEA)

membrane (IEA)

plasma membrane (IEA,ISO)

Molecular Function

folic acid binding (IEA)

folic acid transmembrane transporter activity (IEA)

folic acid:proton symporter activity (IEA)

heme transmembrane transporter activity (IEA,ISO)

methotrexate transmembrane transporter activity (IEA)

proton transmembrane transporter activity (IEA)

symporter activity (IEA)

transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

altered folate cycle metabolic pathway (ISO)

folate cycle metabolic pathway (ISO)

folate metabolic pathway (ISO)

hereditary folate malabsorption pathway (ISO)

methotrexate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SLC46A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	22,164,661 - 22,173,376 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	22,166,318 - 22,173,240 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	7,954,712 - 7,965,674 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SLC46A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	28,394,642 - 28,406,592 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	28,394,642 - 28,407,197 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	26,721,661 - 26,733,230 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	23,745,788 - 23,757,355 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	23,583,422 - 23,594,992 (-)	NCBI		Celera
Cytogenetic Map	17	q11.2	NCBI
HuRef	17	22,930,003 - 22,941,574 (-)	NCBI		HuRef
CHM1_1	17	26,784,574 - 26,796,145 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	29,336,494 - 29,348,065 (-)	NCBI		T2T-CHM13v2.0

Slc46a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	78,356,527 - 78,362,771 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	78,356,523 - 78,362,885 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	78,465,701 - 78,471,945 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	78,465,697 - 78,472,059 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	78,279,203 - 78,285,447 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	78,281,913 - 78,288,125 (+)	NCBI		MGSCv36	mm8
Celera	11	88,097,777 - 88,104,021 (+)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	46.74	NCBI

Slc46a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	63,859,551 - 63,865,987 (+)	NCBI		GRCr8
mRatBN7.2	10	63,361,504 - 63,367,940 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	63,361,486 - 63,368,848 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	67,994,160 - 68,000,596 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	67,499,487 - 67,505,923 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	62,969,164 - 62,975,602 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	65,728,508 - 65,741,708 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	65,733,991 - 65,740,828 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	65,902,790 - 65,915,107 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	64,576,068 - 64,582,504 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	64,589,690 - 64,596,123 (+)	NCBI
Celera	10	62,338,075 - 62,344,511 (+)	NCBI		Celera
Cytogenetic Map	10	q25	NCBI

Slc46a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,734,967 - 4,745,586 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	4,735,325 - 4,741,810 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC46A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	36,052,013 - 36,063,812 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	37,932,238 - 37,944,182 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	28,367,674 - 28,379,618 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	28,870,678 - 28,877,632 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	28,870,678 - 28,877,632 (+)	Ensembl	panpan1.1		panPan2

SLC46A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	42,638,670 - 42,650,241 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	42,643,328 - 42,650,188 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	41,795,562 - 41,807,087 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	43,457,810 - 43,469,341 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	43,457,858 - 43,469,603 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	42,241,834 - 42,252,876 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	42,533,057 - 42,544,655 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	42,610,324 - 42,621,857 (-)	NCBI		UU_Cfam_GSD_1.0

Slc46a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	41,671,087 - 41,763,203 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	4,549,599 - 4,555,415 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	4,549,032 - 4,642,870 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC46A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	44,677,502 - 44,686,250 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	44,677,499 - 44,686,277 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	33,258 - 42,053 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Slc46a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	1,000,444 - 1,007,375 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	1,000,444 - 1,006,984 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	31		33
Low	5	20	27
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008010781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008010782	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000005345 ⟹ ENSCSAP00000003563

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	22,166,318 - 22,173,240 (-)	Ensembl

RefSeq Acc Id:

XM_008010781 ⟹ XP_008008972

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	22,164,661 - 22,173,376 (-)	NCBI
Vero_WHO_p1.0	NW_023666075	7,954,712 - 7,965,674 (+)	NCBI

Sequence:

show sequence

ACATAGTAAGTGGTCAATACATGTTAATTATTGATATTCTTGTTATTTGTGGTGTGTCTGGGCC
GGGAGGGAGGGCTGCAGGGCGCTGTCTATGCACACCTCACAGGTGAGGTCATCCAGCGGGCTGG
GGGTGCCGGGCCCCTCGCCGACCCACGCCCAGCCAGGTGCACCCCCGCGAGAGTCCGGTGGCCT
CAGGTCCCAGGCCCCTCCCCGCCGGACATTTAAGGAGGGACGCTGGGCGCAGGCGCAGAGAGCG
CAAGACCCGCGCCACACGTCGCCAGTCCCAGGCAGCCAGTCGCGCGCGCGCGCGCGCGCGCCCC
GCCGCCCGCCTGGCTACAGCCTCGCTGCGCACACACATGGAGGGGAGCGCGAGTCCCCCGGACA
AGCCCCGCGCCCGTCCCGCGGCTGCTGTGCTGTGCCGGGGCCCGGTAGAGCCGCTGGTCTTCCT
GGCCAACTTTGCCTTGGTCCTGCAGGGCCCGCTCACCACGCAGTATCTGTGGCACCGCTTCAGT
GCCGACCTCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCGGACCCCA
CCATGCAGGAAGTGGAGACCCTTACTTCCCACTGGACCCTCTACATGAACGTGGGCGGCTTCCT
GGTGGGGCTCTTCTCGTCCACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCCCGCTG
CTAGTGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCCATCTTTGTGGTGCAGCTAC
AGCTCCACGTCGGCTACTTCGTGTTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGG
CCTTCTGGCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGCCGCAGCCGCACCTTCCGG
ATGGCCCTGCTGGAAGCCAGCATCGGGGTGGCTGGGATGCTGGCAAGCCTCCTTGGGGGCCACT
GGCTCCGGGCCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTAGCCTTGCTGATAGCCATGAC
ACTCTATGCAGCTTTCTGCTTTGGTGAGACCTTAAAGGAGCCAAAGTCCACCCGGCTCTTCACG
TTCCGTCACCACCGATCCATTGTCCAGCTCTATGTGGCTCCAGCCCCAGAGAAGTCCAGGAAGC
ATTTAGCCCTGTACTCACTGGCCATCTTCGTGGTGATCACTGTGCACTTTGGGGCCCAGGACAT
CTTGACCCTGTATGAACTGAGCACACCCCTCTGCTGGGACTCCAGACTAATCGGCTATGGTTCT
GCAGCTCAGCATCTCCCCTACCTCACCAGCCTGCTGGTCCTGAAGCTCCTGCAGCACTGCCTGG
CCGATGCCTGGGTGGCTGAGATCGGCCTGGCCTTCAACATCCTGGGGATGGTGGTCTTTGCCTT
TGCCACCATCACGCCTCTCATGTTCACAGGATATGGGTTGCTCTTCCTGTCATTGGTCATCACA
CCTGTCATCCGGGCTAAACTCTCCAAGCTGGTGAGAGAGACAGAGCAGGGATGCTGGAAAAGGC
TGTTCCTCACCCTGAGTTCCAGCAGTTTCCCCAGAGCCCCTGATCTGCCTGGACCAGAAGACAG
AGGGCAAGAGGAGCAAAGTGAACACCAAACAACTGAAGGTCTACAGCTGGAGCCCAGCCCACAG
CAGCACCAGCAGCTGCTTTCTAAGGGCAGTGCTCTCTTTGGACGAGGTGGTCAAGACAGACCAA
GGCACCACCCCATCCATAGCTGAGCCAGCCTCTGACTAGGATCTAGAATCATAACCCACACAGG
CCCACTGCAGGACAGGTGGCAGGGGAGCTATTCGGGACAGGAGTCAGTTCTTCCTTTCTGCCAT
CCATCACTTATAACTCCCCAGACCAGAGGAGAGGTCCTGAGGTGACACTTTAGGGACCAGAGGC
AGCACAAGGGCTGGCATCTCTCCTTCCAGCCCAAACTGCACAGTCCCAGGCAGGTTCCTGACAT
GTGTAGCAGTCACCAGCCACTCCTTAACAATGAATGTGGTACCTGGTTAGTGCCAGCCTTGGGA
AGGAGGGAGGGAGGTGAGAGGGGCTTGGTGATCTCCAGAGGAGGAGCGCTGCCTTCACTGTGGT
TGGGGAATTGATCCTTGGCTATGGCCTACCCACTCCCTGGGCTGAAGAGTGCCAATCATTATAA
ATCAGCTTCAGCAAACTGAAACAAACCTTCTGGTGCCGTGGGCTTTGGGGCCCTCTGTTTTCCT
GCTCCCAGTCTGCCTGCCATATGTCAGACAACAGAAGCTGCTGGGCTGGGCAGGAGCCCTGAGC
TGCTTGGTGGACTGATACCAAGTGGGGCCAGCCAGGGCTTCTACTGACTCGCTGTGCAACCTTA
AACAAGCCCCACTAGGAAGGGCTAGATCAGCGATGCCCCGAATTGTTGAATCGTGGTAATCACA
TTTGGACGGACAAGTTAGGAAACTTGGCTGATGCTCTGAGATCTTTCCCACCTCCTCATACATT
CTACAATAAGATGCCTCTCTTCATGGGCCTGGGGAAAGGATGAATGAGTGTGGCTGGACTTTTG
ACCTTTAATGTCCCTGAGCAGTTCTTGGCCCTTGGGGAGAAGTGGGGGGAGGATCTGGCTGACT
CAGCCCCAACCGAGGGGTAGCAGCTGCAGCCCAGCCAAGCAGAACACCCTGGCCCTACAGACCT
GTGTCTGAGTAGGCTTTGGAGGAAAGGCCACTTCTGAGTCCTCTATCTCAGGAGAAGCCAGGCC
TAGGTGCTTGACCTGGTGATCTGAGCTGTGTTTGTCCTAGTGCGGGTGGCAGTCACCTCTGAGC
ACACTGGCCTTGGCTTAGGGGAGGCTTGTGACTTCAGCTGTTCCGTCTGGGGCTGGATGCTGGA
CTCTGATTCCCCCAGAGAGACAGAAGATCGGGCAGAGGTCAACCAGAAGGCCACACAGGGCTGT
GGACAGCAGTGGAGGGTATACCAAACAGAAAAAACACAGGAAACTCTCTGAAGCCTGCCCATGG
GGACCTCAGGAGGGAGTGGGACTGATTGGAGACAAGAAGCCAGAAATCATCCCCTGGAGACACT
CAGACTCTGTATTGTTGTTGACTCTGTCCTGTGAGGGCAGTGTCCAGGCTGCCCTGCTTGTCAC
GTCCATGCCCTCACCCTGGCCCCAGTGAGCACTTGCGCTGCATGAGGAAAGGAAGATCAGATGG
GGTCCAAAGCAAAGCATCGAGGCTGGGACTGGCCAA

hide sequence

RefSeq Acc Id:

XM_008010782 ⟹ XP_008008973

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	22,164,661 - 22,173,372 (-)	NCBI
Vero_WHO_p1.0	NW_023666075	7,954,719 - 7,965,674 (+)	NCBI

Sequence:

show sequence

AGTAAGTGGTCAATACATGTTAATTATTGATATTCTTGTTATTTGTGGTGTGTCTGGGCCGGGA
GGGAGGGCTGCAGGGCGCTGTCTATGCACACCTCACAGGTGAGGTCATCCAGCGGGCTGGGGGT
GCCGGGCCCCTCGCCGACCCACGCCCAGCCAGGTGCACCCCCGCGAGAGTCCGGTGGCCTCAGG
TCCCAGGCCCCTCCCCGCCGGACATTTAAGGAGGGACGCTGGGCGCAGGCGCAGAGAGCGCAAG
ACCCGCGCCACACGTCGCCAGTCCCAGGCAGCCAGTCGCGCGCGCGCGCGCGCGCGCCCCGCCG
CCCGCCTGGCTACAGCCTCGCTGCGCACACACATGGAGGGGAGCGCGAGTCCCCCGGACAAGCC
CCGCGCCCGTCCCGCGGCTGCTGTGCTGTGCCGGGGCCCGGTAGAGCCGCTGGTCTTCCTGGCC
AACTTTGCCTTGGTCCTGCAGGGCCCGCTCACCACGCAGTATCTGTGGCACCGCTTCAGTGCCG
ACCTCGGCTACAATGGCACCCGCCAAAGGGGGGGCTGCAGCAACCGCAGCGCGGACCCCACCAT
GCAGGAAGTGGAGACCCTTACTTCCCACTGGACCCTCTACATGAACGTGGGCGGCTTCCTGGTG
GGGCTCTTCTCGTCCACCCTGCTGGGAGCTTGGAGCGACAGTGTGGGCCGCCGCCCGCTGCTAG
TGCTGGCCTCGCTGGGCCTGCTGCTCCAGGCCCTAGTGTCCATCTTTGTGGTGCAGCTACAGCT
CCACGTCGGCTACTTCGTGTTGGGTCGCATCCTTTGTGCCCTCCTCGGCGACTTCGGTGGCCTT
CTGGCTGCTAGCTTTGCGTCCGTGGCAGATGTCAGCTCCAGCCGCAGCCGCACCTTCCGGATGG
CCCTGCTGGAAGCCAGCATCGGGGTGGCTGGGATGCTGGCAAGCCTCCTTGGGGGCCACTGGCT
CCGGGCCCAGGGTTATGCCAACCCCTTCTGGCTGGCCTTAGCCTTGCTGATAGCCATGACACTC
TATGCAGCTTTCTGCTTTGGTGAGACCTTAAAGGAGCCAAAGTCCACCCGGCTCTTCACGTTCC
GTCACCACCGATCCATTGTCCAGCTCTATGTGGCTCCAGCCCCAGAGAAGTCCAGGAAGCATTT
AGCCCTGTACTCACTGGCCATCTTCGTGGTGATCACTGTGCACTTTGGGGCCCAGGACATCTTG
ACCCTGTATGAACTGAGCACACCCCTCTGCTGGGACTCCAGACTAATCGGCTATGGTTCTGCAG
CTCAGCATCTCCCCTACCTCACCAGCCTGCTGGTCCTGAAGCTCCTGCAGCACTGCCTGGCCGA
TGCCTGGGTGGCTGAGATCGGCCTGGCCTTCAACATCCTGGGGATGGTGGTCTTTGCCTTTGCC
ACCATCACGCCTCTCATGTTCACAGGATATGGGTTGCTCTTCCTGTCATTGGTCATCACACCTG
TCATCCGGGCTAAACTCTCCAAGCTGGTGAGAGAGACAGAGCAGGGTGCTCTCTTTTCTGCTGT
GGCCTGTGTGAATAACCTGGCCATGCTGACGGCCTCCGGCATCTTCAACTCACTCTACCCAGCC
ACTCTGAACTTTATGAAGGGGTTCCCCTTCCTCCTGGGAGCTGGCCTCCTGCTCATCCCGGCCG
TTCTGATTGGGATGCTGGAAAAGGCTGTTCCTCACCCTGAGTTCCAGCAGTTTCCCCAGAGCCC
CTGATCTGCCTGGACCAGAAGACAGAGGGCAAGAGGAGCAAAGTGAACACCAAACAACTGAAGG
TCTACAGCTGGAGCCCAGCCCACAGCAGCACCAGCAGCTGCTTTCTAAGGGCAGTGCTCTCTTT
GGACGAGGTGGTCAAGACAGACCAAGGCACCACCCCATCCATAGCTGAGCCAGCCTCTGACTAG
GATCTAGAATCATAACCCACACAGGCCCACTGCAGGACAGGTGGCAGGGGAGCTATTCGGGACA
GGAGTCAGTTCTTCCTTTCTGCCATCCATCACTTATAACTCCCCAGACCAGAGGAGAGGTCCTG
AGGTGACACTTTAGGGACCAGAGGCAGCACAAGGGCTGGCATCTCTCCTTCCAGCCCAAACTGC
ACAGTCCCAGGCAGGTTCCTGACATGTGTAGCAGTCACCAGCCACTCCTTAACAATGAATGTGG
TACCTGGTTAGTGCCAGCCTTGGGAAGGAGGGAGGGAGGTGAGAGGGGCTTGGTGATCTCCAGA
GGAGGAGCGCTGCCTTCACTGTGGTTGGGGAATTGATCCTTGGCTATGGCCTACCCACTCCCTG
GGCTGAAGAGTGCCAATCATTATAAATCAGCTTCAGCAAACTGAAACAAACCTTCTGGTGCCGT
GGGCTTTGGGGCCCTCTGTTTTCCTGCTCCCAGTCTGCCTGCCATATGTCAGACAACAGAAGCT
GCTGGGCTGGGCAGGAGCCCTGAGCTGCTTGGTGGACTGATACCAAGTGGGGCCAGCCAGGGCT
TCTACTGACTCGCTGTGCAACCTTAAACAAGCCCCACTAGGAAGGGCTAGATCAGCGATGCCCC
GAATTGTTGAATCGTGGTAATCACATTTGGACGGACAAGTTAGGAAACTTGGCTGATGCTCTGA
GATCTTTCCCACCTCCTCATACATTCTACAATAAGATGCCTCTCTTCATGGGCCTGGGGAAAGG
ATGAATGAGTGTGGCTGGACTTTTGACCTTTAATGTCCCTGAGCAGTTCTTGGCCCTTGGGGAG
AAGTGGGGGGAGGATCTGGCTGACTCAGCCCCAACCGAGGGGTAGCAGCTGCAGCCCAGCCAAG
CAGAACACCCTGGCCCTACAGACCTGTGTCTGAGTAGGCTTTGGAGGAAAGGCCACTTCTGAGT
CCTCTATCTCAGGAGAAGCCAGGCCTAGGTGCTTGACCTGGTGATCTGAGCTGTGTTTGTCCTA
GTGCGGGTGGCAGTCACCTCTGAGCACACTGGCCTTGGCTTAGGGGAGGCTTGTGACTTCAGCT
GTTCCGTCTGGGGCTGGATGCTGGACTCTGATTCCCCCAGAGAGACAGAAGATCGGGCAGAGGT
CAACCAGAAGGCCACACAGGGCTGTGGACAGCAGTGGAGGGTATACCAAACAGAAAAAACACAG
GAAACTCTCTGAAGCCTGCCCATGGGGACCTCAGGAGGGAGTGGGACTGATTGGAGACAAGAAG
CCAGAAATCATCCCCTGGAGACACTCAGACTCTGTATTGTTGTTGACTCTGTCCTGTGAGGGCA
GTGTCCAGGCTGCCCTGCTTGTCACGTCCATGCCCTCACCCTGGCCCCAGTGAGCACTTGCGCT
GCATGAGGAAAGGAAGATCAGATGGGGTCCAAAGCAAAGCATCGAGGCTGGGACTGGCCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008008972	(Get FASTA)	NCBI Sequence Viewer
	XP_008008973	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000003563
	ENSCSAP00000003563.1

RefSeq Acc Id:	XP_008008972 ⟸ XM_008010781
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_008008973 ⟸ XM_008010782
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9R4M4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000003563 ⟸ ENSCSAT00000005345

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000007298	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000005345.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/TrEMBL
InterPro	MFS	UniProtKB/TrEMBL
	MFS_dom	UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/TrEMBL
	Sugar_transporter_CS	UniProtKB/TrEMBL
NCBI Gene	SLC46A1	ENTREZGENE
PANTHER	PROTON-COUPLED FOLATE TRANSPORTER	UniProtKB/TrEMBL
	ZGC:174356	UniProtKB/TrEMBL
Pfam	MFS_1	UniProtKB/TrEMBL
PROSITE	MFS	UniProtKB/TrEMBL
	SUGAR_TRANSPORT_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103473	UniProtKB/TrEMBL
UniProt	A0A0D9R4M4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB