LBX2 (ladybird homeobox 2) - Rat Genome Database

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Gene: LBX2 (ladybird homeobox 2) Chlorocebus sabaeus
Analyze
Symbol: LBX2
Name: ladybird homeobox 2
RGD ID: 18781735
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH congenital disorder of glycosylation type IIb (ortholog); dystonia (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor LBX2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,775,196 - 32,780,342 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1432,778,306 - 32,779,931 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604579,390,955 - 79,396,326 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LBX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,775,196 - 32,780,342 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1432,778,306 - 32,779,931 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604579,390,955 - 79,396,326 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LBX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38274,497,517 - 74,503,316 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl274,497,517 - 74,503,316 (-)EnsemblGRCh38hg38GRCh38
GRCh37274,724,644 - 74,730,443 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,578,152 - 74,583,951 (-)NCBINCBI36Build 36hg18NCBI36
Build 34274,636,299 - 74,642,098NCBI
Celera274,555,808 - 74,561,607 (-)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef274,460,905 - 74,466,704 (-)NCBIHuRef
CHM1_1274,654,054 - 74,659,853 (-)NCBICHM1_1
T2T-CHM13v2.0274,506,082 - 74,511,881 (-)NCBIT2T-CHM13v2.0
Lbx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,063,346 - 83,065,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,063,348 - 83,065,224 (+)EnsemblGRCm39 Ensembl
GRCm38683,086,365 - 83,088,243 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,086,367 - 83,088,243 (+)EnsemblGRCm38mm10GRCm38
MGSCv37683,036,359 - 83,038,235 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,052,023 - 83,053,899 (+)NCBIMGSCv36mm8
Celera685,068,944 - 85,070,847 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
Lbx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,149,690 - 117,151,575 (+)NCBIGRCr8
mRatBN7.24115,591,974 - 115,593,859 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,591,974 - 115,594,132 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,068,572 - 121,070,457 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,843,764 - 116,845,649 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,458,358 - 115,460,219 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04113,918,680 - 113,920,565 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,918,740 - 113,920,400 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4114,784,408 - 114,786,293 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04178,603,652 - 178,605,537 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,297,961 - 117,299,846 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4104,586,491 - 104,588,376 (+)NCBICelera
Cytogenetic Map4q34NCBI
Lbx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,289,745 - 11,292,202 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,288,897 - 11,292,143 (+)NCBIChiLan1.0ChiLan1.0
LBX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21251,886,206 - 51,891,663 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A51,887,014 - 51,895,299 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A74,563,221 - 74,569,990 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A76,070,437 - 76,077,451 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A76,070,437 - 76,075,778 (-)Ensemblpanpan1.1panPan2
LBX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,641,630 - 48,643,411 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,641,674 - 48,643,239 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,283,470 - 48,285,322 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01749,501,037 - 49,502,888 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1749,501,151 - 49,502,716 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11748,518,164 - 48,520,013 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01748,584,911 - 48,586,763 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,142,627 - 49,144,479 (+)NCBIUU_Cfam_GSD_1.0
Lbx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629210,024,342 - 10,026,171 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936556711,880 - 713,492 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936556711,279 - 713,530 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LBX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,550,166 - 68,552,043 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,550,219 - 68,552,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,875,242 - 71,876,906 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Lbx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474929,013,146 - 29,014,670 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474929,012,155 - 29,014,681 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 12 1
Below cutoff 8 6 26

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000013742   ⟹   ENSCSAP00000011732
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1432,778,306 - 32,779,931 (+)Ensembl
RefSeq Acc Id: XM_007970130   ⟹   XP_007968321
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11432,775,196 - 32,780,342 (+)NCBI
Vero_WHO_p1.0NW_02366604579,390,955 - 79,393,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038007148   ⟹   XP_037863076
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604579,390,955 - 79,396,326 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007968321 (Get FASTA)   NCBI Sequence Viewer  
  XP_037863076 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011732
  ENSCSAP00000011732.1
Reference Protein Sequences
RefSeq Acc Id: XP_007968321   ⟸   XM_007970130
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RSZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000011732   ⟸   ENSCSAT00000013742
RefSeq Acc Id: XP_037863076   ⟸   XM_038007148
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015648 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013742.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
KEGG Report csab:103220023 UniProtKB/TrEMBL
NCBI Gene LBX2 ENTREZGENE
PANTHER TRANSCRIPTION FACTOR LBX UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR LBX2 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A0D9RSZ3 ENTREZGENE, UniProtKB/TrEMBL