RPH3A (rabphilin 3A) - Rat Genome Database
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Gene: RPH3A (rabphilin 3A) Chlorocebus sabaeus
Analyze
Symbol: RPH3A
Name: rabphilin 3A
RGD ID: 18777857
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); inositol 1,4,5 trisphosphate binding (ortholog); INVOLVED IN brain development (ortholog); dendritic spine organization (ortholog); regulation of NMDA receptor activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cholinergic synapse (ortholog); cytosol (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: rabphilin-3A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl11108,077,043 - 108,155,539 (+)Ensembl
ChlSab1.111107,818,594 - 108,155,546 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

Genomics

Comparative Map Data
RPH3A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl11108,077,043 - 108,155,539 (+)Ensembl
ChlSab1.111107,818,594 - 108,155,546 (+)NCBI
RPH3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12112,570,380 - 112,898,881 (+)EnsemblGRCh38hg38GRCh38
GRCh3812112,575,236 - 112,898,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712113,229,343 - 113,336,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612111,714,125 - 111,819,631 (+)NCBINCBI36hg18NCBI36
Build 3412111,692,461 - 111,797,964NCBI
Celera12112,856,609 - 112,963,778 (+)NCBI
Cytogenetic Map12q24.13NCBI
HuRef12110,241,984 - 110,349,225 (+)NCBIHuRef
CHM1_112113,197,984 - 113,305,112 (+)NCBICHM1_1
Rph3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,078,562 - 121,184,249 (-)NCBIGRCm39mm39
GRCm385120,940,499 - 121,010,116 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5120,940,499 - 121,010,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv375121,390,508 - 121,459,527 (-)NCBIGRCm37mm9NCBIm37
MGSCv365121,201,116 - 121,270,135 (-)NCBImm8
Celera5118,026,782 - 118,095,964 (-)NCBICelera
Cytogenetic Map5FNCBI
Rph3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01241,073,296 - 41,149,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,073,824 - 41,148,490 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,938,832 - 43,014,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,678,613 - 36,753,316 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,542,000 - 36,616,704 (+)NCBI
Celera1237,205,019 - 37,281,023 (+)NCBICelera
Cytogenetic Map12q16NCBI
Rph3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554829,225,845 - 9,312,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554829,190,137 - 9,312,596 (+)NCBIChiLan1.0ChiLan1.0
RPH3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112113,766,871 - 113,888,805 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12113,815,437 - 113,886,701 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012110,393,495 - 110,504,099 (+)NCBIMhudiblu_PPA_v0panPan3
RPH3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2610,280,850 - 10,378,061 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12610,147,910 - 10,379,742 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rph3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366682,827,574 - 2,911,955 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPH3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1438,867,099 - 39,161,537 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11438,867,095 - 39,162,052 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,316,538 - 41,482,994 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rph3a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474719,439,365 - 19,657,865 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 25
Low 34 15 34
Below cutoff 2 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000486   ⟹   ENSCSAP00000015574
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11108,077,043 - 108,155,539 (+)Ensembl
RefSeq Acc Id: XM_008004785   ⟹   XP_008002976
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111108,034,609 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004786   ⟹   XP_008002977
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111108,034,609 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004787   ⟹   XP_008002978
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111107,818,595 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004788   ⟹   XP_008002979
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111108,033,858 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004789   ⟹   XP_008002980
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111107,818,595 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004790   ⟹   XP_008002981
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111107,818,594 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004792   ⟹   XP_008002983
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111107,818,594 - 108,155,546 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004793   ⟹   XP_008002984
RefSeq Status:
Type: CODING
Position:
Vervet AssemblyChrPosition (strand)Source
ChlSab1.111108,034,608 - 108,155,546 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_008002981   ⟸   XM_008004790
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008002983   ⟸   XM_008004792
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008002978   ⟸   XM_008004787
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008002980   ⟸   XM_008004789
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008002979   ⟸   XM_008004788
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008002984   ⟸   XM_008004793
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008002976   ⟸   XM_008004785
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008002977   ⟸   XM_008004786
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000015574   ⟸   ENSCSAT00000000486


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002471 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCSAP00000015574 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000486 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  FYVE_2 UniProtKB/TrEMBL
  Rab_BD UniProtKB/TrEMBL
  Rabphilin/DOC2/Noc2 UniProtKB/TrEMBL
  RPH3A UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene RPH3A ENTREZGENE
PANTHER PTHR45729 UniProtKB/TrEMBL
  PTHR45729:SF3 UniProtKB/TrEMBL
Pfam FYVE_2 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
  SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
  RABBD UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/TrEMBL
UniProt A0A0D9S3Y5_CHLSB UniProtKB/TrEMBL