SIAH1 (siah E3 ubiquitin protein ligase 1)

Gene: SIAH1 (siah E3 ubiquitin protein ligase 1) Chlorocebus sabaeus

Analyze

Symbol:

SIAH1

Name:

siah E3 ubiquitin protein ligase 1

RGD ID:

18776750

Description:

ENCODES a protein that exhibits disordered domain specific binding (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN canonical Wnt signaling pathway (ortholog); male meiosis I (ortholog); neuron apoptotic process (ortholog); ASSOCIATED WITH BURATTI-HAREL SYNDROME (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN beta-catenin destruction complex (ortholog); cytosol (ortholog); early endosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase SIAH1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	34,168,905 - 34,192,548 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	34,169,985 - 34,174,293 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	42,342,435 - 42,366,142 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

BURATTI-HAREL SYNDROME (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Spinal Cord Injuries (ISO)

Spinal Cord Reperfusion Injury (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

canonical Wnt signaling pathway (ISO)

male meiosis I (ISO)

neuron apoptotic process (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of intrinsic apoptotic signaling pathway (ISO)

post-embryonic development (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (IEA)

protein catabolic process (ISO)

protein destabilization (ISO)

protein ubiquitination (IEA)

regulation of multicellular organism growth (ISO)

spermatogenesis (ISO)

ubiquitin-dependent protein catabolic process (IEA,ISO)

Cellular Component

beta-catenin destruction complex (ISO)

cytoplasm (IEA)

cytosol (ISO)

early endosome (ISO)

nucleus (ISO)

SCF ubiquitin ligase complex (ISO)

Molecular Function

disordered domain specific binding (ISO)

identical protein binding (ISO)

metal ion binding (IEA)

protein binding (ISO)

protein homodimerization activity (ISO)

transferase activity (IEA)

ubiquitin conjugating enzyme binding (IEA)

ubiquitin protein ligase activity (IEA)

ubiquitin-protein transferase activity (ISO)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SIAH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	34,168,905 - 34,192,548 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	34,169,985 - 34,174,293 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	42,342,435 - 42,366,142 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SIAH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	48,360,531 - 48,387,246 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	48,356,364 - 48,448,402 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	48,394,442 - 48,419,324 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	46,951,943 - 46,976,730 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	46,951,946 - 46,954,901	NCBI
Celera	16	32,903,789 - 32,928,589 (-)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI
HuRef	16	34,285,181 - 34,290,523 (-)	NCBI		HuRef
CHM1_1	16	49,802,241 - 49,826,886 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	54,157,789 - 54,184,345 (-)	NCBI		T2T-CHM13v2.0

Siah1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	87,442,450 - 87,472,634 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	87,450,635 - 87,472,562 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	86,720,454 - 86,746,006 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	86,724,007 - 86,745,934 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	89,247,832 - 89,269,905 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	89,614,112 - 89,636,039 (-)	NCBI		MGSCv36	mm8
Celera	8	90,989,849 - 91,012,076 (-)	NCBI		Celera
Cytogenetic Map	8	C3	NCBI
cM Map	8	42.1	NCBI

Siah1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	36,552,165 - 36,575,773 (+)	NCBI		GRCr8
mRatBN7.2	19	20,378,908 - 20,402,512 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	20,378,439 - 20,403,808 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	22,064,376 - 22,087,998 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	27,258,868 - 27,282,492 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	30,219,841 - 30,243,426 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	21,372,163 - 21,395,773 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	21,372,163 - 21,395,767 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	32,381,464 - 32,405,074 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	21,717,141 - 21,740,751 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	21,723,004 - 21,745,060 (+)	NCBI
Celera	19	20,251,923 - 20,275,533 (+)	NCBI		Celera
Cytogenetic Map	19	p11	NCBI

Siah1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	6,978,130 - 6,981,189 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955474	6,970,383 - 6,982,231 (+)	NCBI	ChiLan1.0	ChiLan1.0

SIAH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	57,821,104 - 57,845,436 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	63,727,001 - 63,750,803 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	28,627,021 - 28,651,343 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	47,517,587 - 47,542,447 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	47,517,594 - 47,522,936 (-)	Ensembl	panpan1.1		panPan2

SIAH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	66,630,795 - 66,709,497 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	66,657,696 - 66,708,337 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	63,206,954 - 63,285,647 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	67,189,150 - 67,267,733 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	67,210,394 - 67,268,165 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	64,002,793 - 64,081,292 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	65,026,052 - 65,104,768 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	65,914,309 - 65,992,717 (+)	NCBI		UU_Cfam_GSD_1.0

Siah1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	57,910,764 - 58,002,843 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	1,590,004 - 1,594,894 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	1,589,997 - 1,621,506 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SIAH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	36,342,872 - 36,371,383 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	36,337,770 - 36,365,784 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	31,789,161 - 31,853,904 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Siah1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624914	2,166,958 - 2,193,357 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36		44
Low		20	16
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007992468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007992477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007992487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007992497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007992504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007992514	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000003453 ⟹ ENSCSAP00000001732

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	34,169,985 - 34,174,293 (-)	Ensembl

RefSeq Acc Id:

XM_007992468 ⟹ XP_007990659

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	34,168,905 - 34,175,342 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	42,359,734 - 42,366,142 (+)	NCBI

Sequence:

show sequence

ACTGCACTCAGACCTGGGCAACAGTGAGACCCTGTCTCAAGAAAAAAGAAAAAAAAATAGTTCT
GGCACGACTGTGTCTATTTTCAATTATATTTCTTTTCCTAATGTTTTGTGTAGCCTGTATTGTA
AAATGAGGTTGAGGTGATTGGACACACTGTTAATAGAGTGAGGAAGTGGGTAGAGTTAAAATTT
CTTGCTGAAAGTGGGTAATCTGCAGTTCCTTGCATTGGGTTCACTCCTCCCTGCCAGCTCTTGC
TGCATTTGGAGGCTGCCCTAAGCATGATGTAATGACAGGTTAAACCTCTGCACGCACTAGCTGA
TGCAATGCAAATCTGAGGCCCAGGACTTTATTGGGGCAAGGGTGATGCTTGTTTAAAAACAAAA
CAAGCTACTCTGTGTTTAATGAGGCCATTTAAGATGGCTTTCCCAGAGTGGGAAGAGTATAATC
TCTTAGGAGGTTTAAGTAGGAGTTTAATGTGGCAGAAGTGTGCTTACAACTTTTCCTGCGAAGT
CTTTTCACAGCGGGGAAGGAGAGTTTAAAATATAGTGCCCATAGGAGTAGAAATGAAGTGAGCT
AGAATTGAGTAAATATGGTAGTTGATGCCCGGTAAATAGCTGTTGAATGAATTAGGGAGAATGT
TTTCACTCTAAAAATTTAGAGTTTGCACGATGAACCAACAGGGAATGTAGCGCCGGTGTGGGCA
CGCATTTCCCAGATACGCTGTAGCTCTTAGATCGAAACCGTGAGAAACTGCCGATATTCGACTG
TTGTGACCTACCGAAAACAGCATGGTTCTACCTAATTTTAAACTGGTGGAAATGCTGAGGAAGG
CTCGATGTCGCTGGGGTGGGATGGGGTCAACAGCGGGGTGGCGGGGCCCCGCCCTGGGCTGCGG
GGCGGGGCTTGCGGGCACAGCCCCACCCCTGCGCGAGCAAGACGGGCACCGCCCTGCGCGCTGC
GCGCCCTGAGCTGGCCCTGGCGCCCCGGGTTGGAGTGGGCGTTCCCAACGCAGGCCCAGCCCCG
GCCGAGGCTCCAAGTGGCTCTCCAGCAGGCAGGCTTCTGCAGTAGCCCTTGAGCTGGCTCAGGG
AGCGCACTTCCTTCGCAGCGAGCGCATCGCCCCCTGCATCCCCGGCCTCCACCGGAGCTGGGCA
GTAGCCTACGGAGTGAATCTGGAGAAGACAAACTTGGGAGACAGACGAAAGCTTAGGGCACACT
GGAGGACAGCGCAGCTGTGGCTCCCATTTTTGGAGATGCAGCCGAATTTGAGCTCACAGGGAGG
TGTGGTTGCCTCCTGGGGATGGGAAGGCTTCCTTTCTCCACCTCTGTAACTCGTGCTTCTGAGA
AGTAAATGGATATTTGGATCCTGACCTCAGACGCGAATTTGGGTCTTCTGTGCTTAGGAGCAGA
AAGTGCCCAGGAGGGGCCTGTTCCTTTACTTCTTGGGGGAAACGCAATGCGCGGCCTGACTTCT
CATGACGGGAAAGGCTACTCCACCTTCTCTGTACTCCTGGAGGGGAGTCTTGTTCACATGTTTA
CCAGCGGCCAGGACAAGGAAGAGAAAAGAAATGAGCCGTCAGACTGCTACAGCATTACCTACCG
GTACCTCGAAGTGTCCACCATCCCAGAGGGTGCCTGCTCTGACTGGCACAACTGCATCCAACAA
TGACTTGGCGAGTCTTTTTGAGTGTCCGGTCTGCTTTGACTATGTGTTACCACCCATTCTTCAA
TGTCAGAGTGGCCATCTTGTTTGTAGCAACTGTCGCCCAAAGCTCACATGTTGTCCAACTTGCC
GGGGCCCTTTGGGATCCATTCGCAACTTGGCTATGGAGAAAGTGGCTAATTCAGTACTTTTCCC
CTGTAAATATGCCTCTTCTGGATGTGAAATAACTCTGCCACACACAGAAAAAGCAGACCACGAA
GAGCTCTGTGAGTTTAGGCCTTATTCCTGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGGCT
CTCTGGATGCTGTAATGCCCCATCTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGAGA
GGATATAGTTTTCCTTGCTACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATGATGCAG
TCCTGTTTTGGCTTTCACTTCATGTTAGTCTTGGAGAAACAGGAAAAATACGATGGTCACCAGC
AGTTCTTTGCAATCGTACAGCTGATAGGAACACGCAAGCAAGCTGAAAATTTTGCTTACCGACT
TGAGCTAAATGGTCACAGGCGACGATTGACTTGGGAAGCGACTCCTCGATCTATTCATGAAGGA
ATTGCAACAGCCATTATGAATAGCGACTGCCTAGTCTTTGACACCAGCATTGCACAGCTTTTTG
CAGAAAATGGCAATTTAGGCATCAATGTAACTATTTCCATGTGTTGAAATGGCAATCAAACATT
TTCTGGCCAGTGTTTAAAACTTCAGTTTCACAGAAAATAAGGCACCCATCTGCCTGCCAACCTA
AAATTCTTTTGGTAGGTGGAAGCTAGACACATGAAGGTAAATGAAAGGAAAGGCTGTTAAATAC
AGGAAACAGTTGCATGTAGTAACACTAATATATTTAAAAATAAGTCAACAGTAAACCACTGAAA
AAATATATGTATATACACCCAAGATGGGCATCTTTTGTATTAAGAAAGGAAGCATTGTAAAATA
ATTCTGAGTTTTGTGTTTGTTGTAGATTGATTGTATTGTTGAAAAATAGTTTTTTTTTGTTTTG
TTTTTTTGCGTGGGAGTGTGTGCGTGCGTGGGTGTGTGCGTGTTTGGGTTTTTTCCCTTTAACT
GACAAGCCATCTTGAGTGGTCATGGGCCACTGCTTTTCCCCTTTGTGAGTCAATACATAGTGCT
GCTGTGTGCTTTTTTGTGTGTGTATTTGCTAATTTTTATTAATTTTAGTTTTTCATTAAATAAA
TTTGACTTTCTTTTCTGTAATTCAGGTTTTTCTTCACTTTTTTTTGTACCATTTTAAAGTTAGT
GTCTTTTGATATGCATACTTGTTTATGGTAAAAGTTTATAACATGTGTTCAATATTTTCTTTTC
CCCCATTAATCAGTTCATTAGAAATATTTTAAAATCAGCTACTTTGTGAAGCTATGAGTTCCAG
AAAGTAAAGGTGACATCGGAAAAATGATCAAAAGCTATTTAAAGCATCTGTAAGATGGTCTCTC
TCTTTCTCTCTTCTATGGATGAGTCACACCTTTGAGCTTAATCTTTGAAAGGTTAGAGAATAAA
TTGATTTTTATAAGTACTGCAAATCAGGCTTTTGTTTCCTTTTTCAAATATCTTGGATAAATCA
CATGTTTAAAATTTGTTCTTGTATTTATTGGTTTTGCAAAAGAAGGCATCGTCATGCACAGTAT
TTGTAATTAAAAGCAAATCATTTGTTTAAAAAGGCAGTTTGCAAAAAAATGTTTTTGGTCTTTT
ATAATTCTCATTAAAAGAATTTCTGGCAAATTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_007992477 ⟹ XP_007990668

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	34,168,905 - 34,191,620 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	42,343,422 - 42,366,142 (+)	NCBI

Sequence:

show sequence

ATAAGCTGGGCCTCACCGATGCAAATGAGCCGTCAGACTGCTACAGCATTACCTACCGGTACCT
CGAAGTGTCCACCATCCCAGAGGGTGCCTGCTCTGACTGGCACAACTGCATCCAACAATGACTT
GGCGAGTCTTTTTGAGTGTCCGGTCTGCTTTGACTATGTGTTACCACCCATTCTTCAATGTCAG
AGTGGCCATCTTGTTTGTAGCAACTGTCGCCCAAAGCTCACATGTTGTCCAACTTGCCGGGGCC
CTTTGGGATCCATTCGCAACTTGGCTATGGAGAAAGTGGCTAATTCAGTACTTTTCCCCTGTAA
ATATGCCTCTTCTGGATGTGAAATAACTCTGCCACACACAGAAAAAGCAGACCACGAAGAGCTC
TGTGAGTTTAGGCCTTATTCCTGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGGCTCTCTGG
ATGCTGTAATGCCCCATCTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGAGAGGATAT
AGTTTTCCTTGCTACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATGATGCAGTCCTGT
TTTGGCTTTCACTTCATGTTAGTCTTGGAGAAACAGGAAAAATACGATGGTCACCAGCAGTTCT
TTGCAATCGTACAGCTGATAGGAACACGCAAGCAAGCTGAAAATTTTGCTTACCGACTTGAGCT
AAATGGTCACAGGCGACGATTGACTTGGGAAGCGACTCCTCGATCTATTCATGAAGGAATTGCA
ACAGCCATTATGAATAGCGACTGCCTAGTCTTTGACACCAGCATTGCACAGCTTTTTGCAGAAA
ATGGCAATTTAGGCATCAATGTAACTATTTCCATGTGTTGAAATGGCAATCAAACATTTTCTGG
CCAGTGTTTAAAACTTCAGTTTCACAGAAAATAAGGCACCCATCTGCCTGCCAACCTAAAATTC
TTTTGGTAGGTGGAAGCTAGACACATGAAGGTAAATGAAAGGAAAGGCTGTTAAATACAGGAAA
CAGTTGCATGTAGTAACACTAATATATTTAAAAATAAGTCAACAGTAAACCACTGAAAAAATAT
ATGTATATACACCCAAGATGGGCATCTTTTGTATTAAGAAAGGAAGCATTGTAAAATAATTCTG
AGTTTTGTGTTTGTTGTAGATTGATTGTATTGTTGAAAAATAGTTTTTTTTTGTTTTGTTTTTT
TGCGTGGGAGTGTGTGCGTGCGTGGGTGTGTGCGTGTTTGGGTTTTTTCCCTTTAACTGACAAG
CCATCTTGAGTGGTCATGGGCCACTGCTTTTCCCCTTTGTGAGTCAATACATAGTGCTGCTGTG
TGCTTTTTTGTGTGTGTATTTGCTAATTTTTATTAATTTTAGTTTTTCATTAAATAAATTTGAC
TTTCTTTTCTGTAATTCAGGTTTTTCTTCACTTTTTTTTGTACCATTTTAAAGTTAGTGTCTTT
TGATATGCATACTTGTTTATGGTAAAAGTTTATAACATGTGTTCAATATTTTCTTTTCCCCCAT
TAATCAGTTCATTAGAAATATTTTAAAATCAGCTACTTTGTGAAGCTATGAGTTCCAGAAAGTA
AAGGTGACATCGGAAAAATGATCAAAAGCTATTTAAAGCATCTGTAAGATGGTCTCTCTCTTTC
TCTCTTCTATGGATGAGTCACACCTTTGAGCTTAATCTTTGAAAGGTTAGAGAATAAATTGATT
TTTATAAGTACTGCAAATCAGGCTTTTGTTTCCTTTTTCAAATATCTTGGATAAATCACATGTT
TAAAATTTGTTCTTGTATTTATTGGTTTTGCAAAAGAAGGCATCGTCATGCACAGTATTTGTAA
TTAAAAGCAAATCATTTGTTTAAAAAGGCAGTTTGCAAAAAAATGTTTTTGGTCTTTTATAATT
CTCATTAAAAGAATTTCTGGCAAATTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_007992487 ⟹ XP_007990678

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	34,168,905 - 34,192,548 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	42,342,435 - 42,366,142 (+)	NCBI

Sequence:

show sequence

CCCAACGCGCGGGGCCGCGCCTCCTCATGGCCGCCGCCGCAGTGTGTGGTATTTAGCGGGGACG
CGCGGCGGGCTCGAGGACGCGCGAAACGGCGGCGGCGGCGGCGGCCAGGGGGGAGCCGGGGCGG
CCGTTGCGGGGCGCGCTCTCGAGAGGCGGCGGCGGCCCAGAGTGTCCCGTCGGTCTCGGCGCCG
GGAAGAGGCGGTGGCGCTGCCCGCGGTGGCGGGGGTTGGCGACGGAGCGCGTTGGTGCCAGGAC
CGGGGTCCGAGGCGCGCTCTCCGCCCACAGAAATGAGCCGTCAGACTGCTACAGCATTACCTAC
CGGTACCTCGAAGTGTCCACCATCCCAGAGGGTGCCTGCTCTGACTGGCACAACTGCATCCAAC
AATGACTTGGCGAGTCTTTTTGAGTGTCCGGTCTGCTTTGACTATGTGTTACCACCCATTCTTC
AATGTCAGAGTGGCCATCTTGTTTGTAGCAACTGTCGCCCAAAGCTCACATGTTGTCCAACTTG
CCGGGGCCCTTTGGGATCCATTCGCAACTTGGCTATGGAGAAAGTGGCTAATTCAGTACTTTTC
CCCTGTAAATATGCCTCTTCTGGATGTGAAATAACTCTGCCACACACAGAAAAAGCAGACCACG
AAGAGCTCTGTGAGTTTAGGCCTTATTCCTGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGG
CTCTCTGGATGCTGTAATGCCCCATCTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGA
GAGGATATAGTTTTCCTTGCTACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATGATGC
AGTCCTGTTTTGGCTTTCACTTCATGTTAGTCTTGGAGAAACAGGAAAAATACGATGGTCACCA
GCAGTTCTTTGCAATCGTACAGCTGATAGGAACACGCAAGCAAGCTGAAAATTTTGCTTACCGA
CTTGAGCTAAATGGTCACAGGCGACGATTGACTTGGGAAGCGACTCCTCGATCTATTCATGAAG
GAATTGCAACAGCCATTATGAATAGCGACTGCCTAGTCTTTGACACCAGCATTGCACAGCTTTT
TGCAGAAAATGGCAATTTAGGCATCAATGTAACTATTTCCATGTGTTGAAATGGCAATCAAACA
TTTTCTGGCCAGTGTTTAAAACTTCAGTTTCACAGAAAATAAGGCACCCATCTGCCTGCCAACC
TAAAATTCTTTTGGTAGGTGGAAGCTAGACACATGAAGGTAAATGAAAGGAAAGGCTGTTAAAT
ACAGGAAACAGTTGCATGTAGTAACACTAATATATTTAAAAATAAGTCAACAGTAAACCACTGA
AAAAATATATGTATATACACCCAAGATGGGCATCTTTTGTATTAAGAAAGGAAGCATTGTAAAA
TAATTCTGAGTTTTGTGTTTGTTGTAGATTGATTGTATTGTTGAAAAATAGTTTTTTTTTGTTT
TGTTTTTTTGCGTGGGAGTGTGTGCGTGCGTGGGTGTGTGCGTGTTTGGGTTTTTTCCCTTTAA
CTGACAAGCCATCTTGAGTGGTCATGGGCCACTGCTTTTCCCCTTTGTGAGTCAATACATAGTG
CTGCTGTGTGCTTTTTTGTGTGTGTATTTGCTAATTTTTATTAATTTTAGTTTTTCATTAAATA
AATTTGACTTTCTTTTCTGTAATTCAGGTTTTTCTTCACTTTTTTTTGTACCATTTTAAAGTTA
GTGTCTTTTGATATGCATACTTGTTTATGGTAAAAGTTTATAACATGTGTTCAATATTTTCTTT
TCCCCCATTAATCAGTTCATTAGAAATATTTTAAAATCAGCTACTTTGTGAAGCTATGAGTTCC
AGAAAGTAAAGGTGACATCGGAAAAATGATCAAAAGCTATTTAAAGCATCTGTAAGATGGTCTC
TCTCTTTCTCTCTTCTATGGATGAGTCACACCTTTGAGCTTAATCTTTGAAAGGTTAGAGAATA
AATTGATTTTTATAAGTACTGCAAATCAGGCTTTTGTTTCCTTTTTCAAATATCTTGGATAAAT
CACATGTTTAAAATTTGTTCTTGTATTTATTGGTTTTGCAAAAGAAGGCATCGTCATGCACAGT
ATTTGTAATTAAAAGCAAATCATTTGTTTAAAAAGGCAGTTTGCAAAAAAATGTTTTTGGTCTT
TTATAATTCTCATTAAAAGAATTTCTGGCAAATTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_007992497 ⟹ XP_007990688

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	34,168,905 - 34,192,015 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	42,343,023 - 42,366,142 (+)	NCBI

Sequence:

show sequence

TGTTGTGGAGGGTCCCGGGGTGTGCGGCCAACATGGCGGAGGTCAGCTGAGTGCGGGCAGCTGC
CGGGGCCCTGCCCTCCCTCCCCACGGCGCCCGGAGGCCCGGGCCGCACCGCGCCGCTCGGCCGG
CCTCGGTCTCGTTTCTCTGCCCCCGACACCCGGCTGGAGCCGTCCCGGACGGGGCTGCGCTCTT
CCTGCCGCTTCGGCCGGAGGCTTCATTGTGCAGTGGGAAGAATGCAGCCTCCTCCCTTGTTTAT
GTCGTTAGAGAAGAGAGCGCGTGAACGGCGTGCCGGGGAAGCTCTGGCTTATTATAAACCTGGC
ATTTCCTAGGCTTCATTTGCCGGAAATGAGCCGTCAGACTGCTACAGCATTACCTACCGGTACC
TCGAAGTGTCCACCATCCCAGAGGGTGCCTGCTCTGACTGGCACAACTGCATCCAACAATGACT
TGGCGAGTCTTTTTGAGTGTCCGGTCTGCTTTGACTATGTGTTACCACCCATTCTTCAATGTCA
GAGTGGCCATCTTGTTTGTAGCAACTGTCGCCCAAAGCTCACATGTTGTCCAACTTGCCGGGGC
CCTTTGGGATCCATTCGCAACTTGGCTATGGAGAAAGTGGCTAATTCAGTACTTTTCCCCTGTA
AATATGCCTCTTCTGGATGTGAAATAACTCTGCCACACACAGAAAAAGCAGACCACGAAGAGCT
CTGTGAGTTTAGGCCTTATTCCTGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGGCTCTCTG
GATGCTGTAATGCCCCATCTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGAGAGGATA
TAGTTTTCCTTGCTACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATGATGCAGTCCTG
TTTTGGCTTTCACTTCATGTTAGTCTTGGAGAAACAGGAAAAATACGATGGTCACCAGCAGTTC
TTTGCAATCGTACAGCTGATAGGAACACGCAAGCAAGCTGAAAATTTTGCTTACCGACTTGAGC
TAAATGGTCACAGGCGACGATTGACTTGGGAAGCGACTCCTCGATCTATTCATGAAGGAATTGC
AACAGCCATTATGAATAGCGACTGCCTAGTCTTTGACACCAGCATTGCACAGCTTTTTGCAGAA
AATGGCAATTTAGGCATCAATGTAACTATTTCCATGTGTTGAAATGGCAATCAAACATTTTCTG
GCCAGTGTTTAAAACTTCAGTTTCACAGAAAATAAGGCACCCATCTGCCTGCCAACCTAAAATT
CTTTTGGTAGGTGGAAGCTAGACACATGAAGGTAAATGAAAGGAAAGGCTGTTAAATACAGGAA
ACAGTTGCATGTAGTAACACTAATATATTTAAAAATAAGTCAACAGTAAACCACTGAAAAAATA
TATGTATATACACCCAAGATGGGCATCTTTTGTATTAAGAAAGGAAGCATTGTAAAATAATTCT
GAGTTTTGTGTTTGTTGTAGATTGATTGTATTGTTGAAAAATAGTTTTTTTTTGTTTTGTTTTT
TTGCGTGGGAGTGTGTGCGTGCGTGGGTGTGTGCGTGTTTGGGTTTTTTCCCTTTAACTGACAA
GCCATCTTGAGTGGTCATGGGCCACTGCTTTTCCCCTTTGTGAGTCAATACATAGTGCTGCTGT
GTGCTTTTTTGTGTGTGTATTTGCTAATTTTTATTAATTTTAGTTTTTCATTAAATAAATTTGA
CTTTCTTTTCTGTAATTCAGGTTTTTCTTCACTTTTTTTTGTACCATTTTAAAGTTAGTGTCTT
TTGATATGCATACTTGTTTATGGTAAAAGTTTATAACATGTGTTCAATATTTTCTTTTCCCCCA
TTAATCAGTTCATTAGAAATATTTTAAAATCAGCTACTTTGTGAAGCTATGAGTTCCAGAAAGT
AAAGGTGACATCGGAAAAATGATCAAAAGCTATTTAAAGCATCTGTAAGATGGTCTCTCTCTTT
CTCTCTTCTATGGATGAGTCACACCTTTGAGCTTAATCTTTGAAAGGTTAGAGAATAAATTGAT
TTTTATAAGTACTGCAAATCAGGCTTTTGTTTCCTTTTTCAAATATCTTGGATAAATCACATGT
TTAAAATTTGTTCTTGTATTTATTGGTTTTGCAAAAGAAGGCATCGTCATGCACAGTATTTGTA
ATTAAAAGCAAATCATTTGTTTAAAAAGGCAGTTTGCAAAAAAATGTTTTTGGTCTTTTATAAT
TCTCATTAAAAGAATTTCTGGCAAATTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_007992504 ⟹ XP_007990695

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	34,168,905 - 34,177,012 (-)	NCBI
Vero_WHO_p1.0	NW_023666047	42,358,019 - 42,366,142 (+)	NCBI

Sequence:

show sequence

TCCTCCCAAAGTGCTGGGATTACAGAAATGAGCCGTCAGACTGCTACAGCATTACCTACCGGTA
CCTCGAAGTGTCCACCATCCCAGAGGGTGCCTGCTCTGACTGGCACAACTGCATCCAACAATGA
CTTGGCGAGTCTTTTTGAGTGTCCGGTCTGCTTTGACTATGTGTTACCACCCATTCTTCAATGT
CAGAGTGGCCATCTTGTTTGTAGCAACTGTCGCCCAAAGCTCACATGTTGTCCAACTTGCCGGG
GCCCTTTGGGATCCATTCGCAACTTGGCTATGGAGAAAGTGGCTAATTCAGTACTTTTCCCCTG
TAAATATGCCTCTTCTGGATGTGAAATAACTCTGCCACACACAGAAAAAGCAGACCACGAAGAG
CTCTGTGAGTTTAGGCCTTATTCCTGTCCGTGCCCTGGTGCTTCCTGTAAATGGCAAGGCTCTC
TGGATGCTGTAATGCCCCATCTGATGCATCAGCATAAGTCCATTACAACCCTACAGGGAGAGGA
TATAGTTTTCCTTGCTACAGACATTAATCTTCCTGGTGCTGTTGACTGGGTGATGATGCAGTCC
TGTTTTGGCTTTCACTTCATGTTAGTCTTGGAGAAACAGGAAAAATACGATGGTCACCAGCAGT
TCTTTGCAATCGTACAGCTGATAGGAACACGCAAGCAAGCTGAAAATTTTGCTTACCGACTTGA
GCTAAATGGTCACAGGCGACGATTGACTTGGGAAGCGACTCCTCGATCTATTCATGAAGGAATT
GCAACAGCCATTATGAATAGCGACTGCCTAGTCTTTGACACCAGCATTGCACAGCTTTTTGCAG
AAAATGGCAATTTAGGCATCAATGTAACTATTTCCATGTGTTGAAATGGCAATCAAACATTTTC
TGGCCAGTGTTTAAAACTTCAGTTTCACAGAAAATAAGGCACCCATCTGCCTGCCAACCTAAAA
TTCTTTTGGTAGGTGGAAGCTAGACACATGAAGGTAAATGAAAGGAAAGGCTGTTAAATACAGG
AAACAGTTGCATGTAGTAACACTAATATATTTAAAAATAAGTCAACAGTAAACCACTGAAAAAA
TATATGTATATACACCCAAGATGGGCATCTTTTGTATTAAGAAAGGAAGCATTGTAAAATAATT
CTGAGTTTTGTGTTTGTTGTAGATTGATTGTATTGTTGAAAAATAGTTTTTTTTTGTTTTGTTT
TTTTGCGTGGGAGTGTGTGCGTGCGTGGGTGTGTGCGTGTTTGGGTTTTTTCCCTTTAACTGAC
AAGCCATCTTGAGTGGTCATGGGCCACTGCTTTTCCCCTTTGTGAGTCAATACATAGTGCTGCT
GTGTGCTTTTTTGTGTGTGTATTTGCTAATTTTTATTAATTTTAGTTTTTCATTAAATAAATTT
GACTTTCTTTTCTGTAATTCAGGTTTTTCTTCACTTTTTTTTGTACCATTTTAAAGTTAGTGTC
TTTTGATATGCATACTTGTTTATGGTAAAAGTTTATAACATGTGTTCAATATTTTCTTTTCCCC
CATTAATCAGTTCATTAGAAATATTTTAAAATCAGCTACTTTGTGAAGCTATGAGTTCCAGAAA
GTAAAGGTGACATCGGAAAAATGATCAAAAGCTATTTAAAGCATCTGTAAGATGGTCTCTCTCT
TTCTCTCTTCTATGGATGAGTCACACCTTTGAGCTTAATCTTTGAAAGGTTAGAGAATAAATTG
ATTTTTATAAGTACTGCAAATCAGGCTTTTGTTTCCTTTTTCAAATATCTTGGATAAATCACAT
GTTTAAAATTTGTTCTTGTATTTATTGGTTTTGCAAAAGAAGGCATCGTCATGCACAGTATTTG
TAATTAAAAGCAAATCATTTGTTTAAAAAGGCAGTTTGCAAAAAAATGTTTTTGGTCTTTTATA
ATTCTCATTAAAAGAATTTCTGGCAAATTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_038008519 ⟹ XP_037864447

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666047	42,343,461 - 42,366,142 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_007990659	(Get FASTA)	NCBI Sequence Viewer
	XP_007990668	(Get FASTA)	NCBI Sequence Viewer
	XP_007990678	(Get FASTA)	NCBI Sequence Viewer
	XP_007990688	(Get FASTA)	NCBI Sequence Viewer
	XP_007990695	(Get FASTA)	NCBI Sequence Viewer
	XP_037864447	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000001732
	ENSCSAP00000001732.1

RefSeq Acc Id:	XP_007990678 ⟸ XM_007992487
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_007990688 ⟸ XM_007992497
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_007990668 ⟸ XM_007992477
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_007990695 ⟸ XM_007992504
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_007990659 ⟸ XM_007992468
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QZE3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000001732 ⟸ ENSCSAT00000003453

RefSeq Acc Id:	XP_037864447 ⟸ XM_038008519
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005422	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000003453.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
InterPro	7-in-absentia-prot_TRAF-dom	UniProtKB/TrEMBL
	SINA-like	UniProtKB/TrEMBL
	Sina-like_RING	UniProtKB/TrEMBL
	TRAF-like	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_SIAH	UniProtKB/TrEMBL
KEGG Report	csab:103232443	UniProtKB/TrEMBL
NCBI Gene	SIAH1	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE SIAH1	UniProtKB/TrEMBL
	PTHR45877	UniProtKB/TrEMBL
Pfam	Sina	UniProtKB/TrEMBL
	Sina_RING	UniProtKB/TrEMBL
	Sina_ZnF	UniProtKB/TrEMBL
PROSITE	ZF_RING_2	UniProtKB/TrEMBL
	ZF_SIAH	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	TRAF domain-like	UniProtKB/TrEMBL
UniProt	A0A0D9QZE3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM