TRIM16 (tripartite motif containing 16) - Rat Genome Database

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Gene: TRIM16 (tripartite motif containing 16) Chlorocebus sabaeus
Analyze
Symbol: TRIM16
Name: tripartite motif containing 16
RGD ID: 18776148
Description: ENCODES a protein that exhibits DNA binding (inferred); interleukin-1 binding (inferred); NACHT domain binding (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); positive regulation of interleukin-1 beta production (inferred); positive regulation of keratinocyte differentiation (inferred); ASSOCIATED WITH genetic disease (ortholog); Ovarian Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103242430; tripartite motif-containing protein 16; zinc finger protein ZFP69-like; zinc finger protein ZFP69B-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11614,874,159 - 14,897,958 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1614,871,657 - 14,897,865 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660596,251,363 - 6,307,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
plasma membrane  (IEA)
PML body  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TRIM16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11614,874,159 - 14,897,958 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1614,871,657 - 14,897,865 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660596,251,363 - 6,307,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRIM16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381715,627,966 - 15,684,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1715,627,960 - 15,684,311 (-)EnsemblGRCh38hg38GRCh38
GRCh371715,531,280 - 15,587,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361715,472,005 - 15,526,918 (-)NCBINCBI36Build 36hg18NCBI36
Build 341715,472,005 - 15,526,918NCBI
Cytogenetic Map17p12NCBI
HuRef1715,404,775 - 15,461,210 (-)NCBIHuRef
CHM1_11715,540,352 - 15,595,047 (-)NCBICHM1_1
T2T-CHM13v2.01715,534,188 - 15,590,551 (-)NCBIT2T-CHM13v2.0
Trim16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,711,034 - 62,733,774 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,711,057 - 62,741,634 (+)EnsemblGRCm39 Ensembl
GRCm381162,820,198 - 62,842,948 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,820,231 - 62,850,808 (+)EnsemblGRCm38mm10GRCm38
MGSCv371162,633,755 - 62,656,450 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,636,448 - 62,659,143 (+)NCBIMGSCv36mm8
Celera1169,742,229 - 69,768,302 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1138.75NCBI
Trim16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,985,235 - 48,008,242 (+)NCBIGRCr8
mRatBN7.21047,485,982 - 47,509,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1047,486,297 - 47,551,907 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1052,189,625 - 52,212,030 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,680,165 - 51,702,570 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01047,183,586 - 47,205,991 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01049,231,660 - 49,254,653 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1049,231,730 - 49,254,621 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01049,011,305 - 49,033,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41048,987,004 - 49,009,696 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11049,000,664 - 49,021,215 (+)NCBI
Celera1046,731,462 - 46,754,204 (+)NCBICelera
Cytogenetic Map10q23NCBI
Trim16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554672,059,777 - 2,085,206 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554672,059,793 - 2,084,221 (+)NCBIChiLan1.0ChiLan1.0
TRIM16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21958,070,809 - 58,127,342 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11762,877,474 - 62,934,040 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01735,973,775 - 36,028,767 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TRIM16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,146,505 - 39,167,857 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,148,868 - 39,213,203 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha539,291,568 - 39,312,872 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0539,254,975 - 39,276,316 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,254,781 - 39,321,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,227,812 - 39,249,105 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,173,103 - 39,194,393 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0539,361,457 - 39,382,765 (-)NCBIUU_Cfam_GSD_1.0
Trim16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560258,132,028 - 58,170,647 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367242,088,370 - 2,122,170 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367242,101,942 - 2,122,747 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1258,926,086 - 58,939,745 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11258,926,083 - 58,940,642 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Trim16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248773,672,925 - 3,713,783 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248773,688,635 - 3,713,718 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 12 60
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000006986   ⟹   ENSCSAP00000005177
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1614,871,657 - 14,897,865 (-)Ensembl
RefSeq Acc Id: XM_008010449   ⟹   XP_008008640
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11614,874,159 - 14,897,958 (-)NCBI
Vero_WHO_p1.0NW_0236660596,283,783 - 6,307,344 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037987288   ⟹   XP_037843216
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660596,293,439 - 6,307,344 (+)NCBI
RefSeq Acc Id: XM_037987289   ⟹   XP_037843217
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660596,251,363 - 6,256,607 (+)NCBI
RefSeq Acc Id: XM_037987290   ⟹   XP_037843218
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660596,251,371 - 6,307,941 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008008640 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843216 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843217 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843218 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005177.1
Reference Protein Sequences
RefSeq Acc Id: XP_008008640   ⟸   XM_008010449
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R988 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000005177   ⟸   ENSCSAT00000006986
RefSeq Acc Id: XP_037843217   ⟸   XM_037987289
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037843218   ⟸   XM_037987290
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037843216   ⟸   XM_037987288
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008919 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006986.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  4.10.830.40 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
KEGG Report csab:103242431 UniProtKB/TrEMBL
NCBI Gene TRIM16 ENTREZGENE
PANTHER B-BOX DOMAIN CONTAINING UniProtKB/TrEMBL
  TRIPARTITE MOTIF-CONTAINING PROTEIN 16-RELATED UniProtKB/TrEMBL
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A0D9R988 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 TRIM16  tripartite motif containing 16  LOC103242430  zinc finger protein ZFP69-like  Data merged from RGD:18459926 737654 PROVISIONAL