INHBE (inhibin subunit beta E) - Rat Genome Database

Name: INHBE
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: INHBE (inhibin subunit beta E) Chlorocebus sabaeus

Analyze

Symbol:

INHBE

Name:

inhibin subunit beta E

RGD ID:

18774897

Description:

ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); hormone activity (inferred); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); familial melanoma (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

inhibin beta E chain; inhibin beta E subunit

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	INHBE (inhibin subunit beta E)	NCBI	Ortholog
Mus musculus (house mouse):	Inhbe (inhibin beta-E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Inhbe (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Inhbe (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	INHBE (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	INHBE (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Inhbe (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	INHBE (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Inhbe (inhibin subunit beta E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	53,367,304 - 53,369,205 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	53,367,423 - 53,370,322 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	192,597,371 - 192,599,709 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

familial melanoma (ISO)

genetic disease (ISO)

lipid storage disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

signal transduction (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

cytokine activity (IEA)

growth factor activity (IEA)

hormone activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

INHBE
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	53,367,304 - 53,369,205 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	53,367,423 - 53,370,322 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	192,597,371 - 192,599,709 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

INHBE
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	57,455,307 - 57,458,025 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	57,452,323 - 57,459,280 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	57,849,090 - 57,851,808 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	56,135,363 - 56,138,058 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	56,135,362 - 56,138,056	NCBI
Celera	12	57,503,083 - 57,505,778 (+)	NCBI		Celera
Cytogenetic Map	12	q13.3	NCBI
HuRef	12	54,886,854 - 54,889,664 (+)	NCBI		HuRef
CHM1_1	12	57,817,205 - 57,819,905 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	57,423,596 - 57,426,314 (+)	NCBI		T2T-CHM13v2.0

Inhbe
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	127,185,271 - 127,187,717 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	127,184,726 - 127,190,280 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	127,349,402 - 127,351,848 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	127,348,857 - 127,354,411 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	126,786,458 - 126,788,828 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	126,752,351 - 126,754,721 (-)	NCBI		MGSCv36	mm8
Celera	10	129,741,900 - 129,744,264 (-)	NCBI		Celera
Cytogenetic Map	10	D3	NCBI
cM Map	10	74.5	NCBI

Inhbe
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	65,061,531 - 65,064,519 (-)	NCBI		GRCr8
mRatBN7.2	7	63,176,221 - 63,179,209 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	63,176,219 - 63,179,172 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	65,066,840 - 65,068,267 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	67,269,266 - 67,270,691 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	67,070,582 - 67,072,002 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	70,641,423 - 70,642,848 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	70,640,075 - 70,643,169 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	70,815,702 - 70,817,127 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	67,308,713 - 67,310,138 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	67,328,105 - 67,331,057 (-)	NCBI
Celera	7	60,317,558 - 60,318,983 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

Inhbe
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	5,177,036 - 5,179,095 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	5,177,036 - 5,179,095 (+)	NCBI	ChiLan1.0	ChiLan1.0

INHBE
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	36,882,466 - 36,884,975 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	36,877,499 - 36,881,728 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	31,467,974 - 31,470,700 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	31,724,247 - 31,726,978 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	31,724,252 - 31,726,978 (-)	Ensembl	panpan1.1		panPan2

INHBE
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	1,558,876 - 1,563,370 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	1,559,770 - 1,562,885 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	1,622,273 - 1,626,266 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	1,568,055 - 1,572,048 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	1,568,174 - 1,572,796 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	1,546,151 - 1,550,142 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	1,787,658 - 1,791,648 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	1,912,977 - 1,916,971 (+)	NCBI		UU_Cfam_GSD_1.0

Inhbe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	57,253,345 - 57,256,317 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	1,614,745 - 1,616,279 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	1,614,902 - 1,616,482 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

INHBE
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	22,732,516 - 22,734,083 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	22,732,774 - 22,734,716 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	24,808,794 - 24,811,612 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Inhbe
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624802	10,493,576 - 10,499,565 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624802	10,497,618 - 10,499,433 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low	1	16	8
Below cutoff	24	4	51

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008003776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000002932 ⟹ ENSCSAP00000001224

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	11	53,367,423 - 53,370,322 (+)	Ensembl

RefSeq Acc Id:

XM_008003776 ⟹ XP_008001967

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	11	53,367,304 - 53,369,205 (+)	NCBI
Vero_WHO_p1.0	NW_023666037	192,597,371 - 192,599,709 (-)	NCBI

Sequence:

show sequence

CCCTGCAGGGGCCTGATGGGCAGCACAGCTGGCCAATCCTGGGACTCAGAGGGTAGGTCGGCTG
GCTGACCACTAGGTTTGGAAGCCCCAGGCAGCTGGCTCTAAAAAGGCCCCAGGTCAGTAGCCAG
ACATGAGCTGTGAGGGTCAAGCACAGCTATCCATCAGATGATCTACTTTCAGCCTTCCTGAGTC
CCAGGCAATAGAAGACAGGTGGCTCTACCCTTGGCCAAGGGTGGGTGTGGCAGTGGTGTCTGCT
GTCACTGTGCCTTCATTGGCCCCCAGCAATCAGACTCAACAGACGGAGCAACTGCCATCCGAGG
CTCCCGAACCAGGGCCATTCACCAGGAGCATGGGGCTCCCTGATGTCCAGCTCTGGCTGGTGCT
GCTGTGGACACTGGTGCGGGCACAGGGGACAGGGTCTGTGTGTCCCTCCTGTGGGGGCTCCAAA
CTGGCACCCCAAGCAGAACGAGCTCTGGTGCTGGAGCTAGCCAAGCAGCAAATCCTGGAGGGGT
TGCACCTGACCAGTCGTCCCAGAATAACTCATCCTCCACCCCAGGCAGCGCTGACCAGAGCCCT
CCGGAGACTACAGCCGGGGAGTGTGGCTCCAGGGAATGGGGAGGAGGTCATCAGCTTTGCTACT
GTCACAGACTCCACTTCAGCCTACAGCTCCCTGCTTACCTTTCACCTGTCCACTCCTCGGTCCC
ATCACCTGTACCATGCCCGCCTGTGGCTGCACGTGCTCCCCACCCTTCCTGGCACTCTTTGCTT
GAGGATCTTCCGATGGGGACCAAGGAGGAGGCACCAAGGGTCCCGCACCCTTCTGGCTGAGCAC
CACATCACCAACCTGGGCTGGCATGCCTTAACTCTGCCCTCTAGTGGCTTGAGGTGTGAGAAGT
CTGGTGTCCTGAAACTGCAACTAGACTGCAGACCCCTAGAAGGCAACAACAGCACAGTTACTGG
ACAACCAAGGCGGCTCCTGGACACAGCAGGACACCAGCAGCCCTTCCTAGAGCTTAAGATCCGA
GCCAATGAGCCTGGAGCAGGTCGGGCCAGGAGGAGGACCCCCACCTGTGAGCCTGCAACCCCCT
TATGTTGCAGGCGAGACCATTACGTAGACTTCCAGGAACTGGGATGGCGGGACTGGATACTGCA
ACCCGAGGGGTACCAGCTGAATTACTGCAGTGGGCAGTGCCCTCCCCACCTGGCTGGCAGTCCA
GGCATTGCTGCCTCTTTCCATTCTGCCGTCTTCAGCCTCCTCAAAGCCAACAATCCTTGGCCTG
CCAGTACCTCCTGCTGTGTCCCTACTGCCCGAAGGCCCCTTTCTCTCCTCTACCTGGATCATAA
TGGCAATGTGGTCAAGACGGATGTGCCAGATATGGTGGTGGAGGCCTGTGGCTGCAGCTAGCAA
GAGGACCTGGGGCTTTGGAGTGAAGAGACCAAGATGAAGTTTCCCAGGCACAGGGCATCTGTGG
CTGGAGGCATCAGATTCCTGATCCACACCCCAACCCAACAACCACCTGGCAATATGACTCACTT
GACCCCTATGGGACCCAAATGGGCACTTTCTTGTCTGAGACTCTGGCTTGTTCCAGGTTGGCTG
ATGTGTTGGCAGATGGGTAAAGCATTTCTTCTAAAGGGGTCTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008001967	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000001224
	ENSCSAP00000001224.1

RefSeq Acc Id:	XP_008001967 ⟸ XM_008003776
- UniProtKB:	A0A0D9QXY5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000001224 ⟸ ENSCSAT00000002932

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004900	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002932.1	UniProtKB/TrEMBL
Gene3D-CATH	2.10.90.10	UniProtKB/TrEMBL
InterPro	Cystine-knot_cytokine	UniProtKB/TrEMBL
	Inhibin_betaC	UniProtKB/TrEMBL
	TGF-b_C	UniProtKB/TrEMBL
	TGF-beta-rel	UniProtKB/TrEMBL
	TGFb_CS	UniProtKB/TrEMBL
KEGG Report	csab:103238565	UniProtKB/TrEMBL
NCBI Gene	INHBE	ENTREZGENE
PANTHER	INHIBIN BETA E CHAIN	UniProtKB/TrEMBL
	PTHR11848	UniProtKB/TrEMBL
Pfam	TGF_beta	UniProtKB/TrEMBL
PRINTS	INHIBINBC	UniProtKB/TrEMBL
PROSITE	TGF_BETA_1	UniProtKB/TrEMBL
	TGF_BETA_2	UniProtKB/TrEMBL
SMART	TGFB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57501	UniProtKB/TrEMBL
UniProt	A0A0D9QXY5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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