OAF (out at first homolog) - Rat Genome Database

Name: OAF
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: OAF (out at first homolog) Chlorocebus sabaeus

Analyze

Symbol:

OAF

Name:

out at first homolog

RGD ID:

18763835

Description:

ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

out at first protein homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OAF (out at first homolog)	NCBI	Ortholog
Mus musculus (house mouse):	Oaf (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Oaf (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Oaf (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OAF (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	OAF (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Oaf (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OAF (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Oaf (out at first homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	111,614,890 - 111,634,309 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	111,615,001 - 111,638,431 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	14,425,828 - 14,444,899 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CD3epsilon deficiency (ISO)

Chromosome 11, Partial Trisomy 11q (ISO)

Dwarfism (ISO)

genetic disease (ISO)

immunodeficiency 17 (ISO)

immunodeficiency 18 (ISO)

immunodeficiency 19 (ISO)

inflammatory bowel disease 28 (ISO)

isolated microphthalmia 5 (ISO)

RASopathy (ISO)

schizophrenia (ISO)

References

Genomics

Comparative Map Data

OAF
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	111,614,890 - 111,634,309 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	111,615,001 - 111,638,431 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	14,425,828 - 14,444,899 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

OAF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	120,211,032 - 120,230,334 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	120,211,032 - 120,230,334 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	120,081,740 - 120,101,043 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	119,586,957 - 119,605,860 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	117,239,997 - 117,258,863 (+)	NCBI		Celera
Cytogenetic Map	11	q23.3	NCBI
HuRef	11	116,021,485 - 116,040,231 (+)	NCBI		HuRef
CHM1_1	11	119,969,201 - 119,988,096 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	120,233,870 - 120,253,135 (+)	NCBI		T2T-CHM13v2.0

Oaf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	43,132,575 - 43,151,113 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	43,132,532 - 43,151,208 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	43,221,278 - 43,239,816 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	43,221,235 - 43,239,911 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	43,029,361 - 43,047,899 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	42,972,273 - 42,990,811 (-)	NCBI		MGSCv36	mm8
Celera	9	40,474,322 - 40,492,817 (-)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	24.24	NCBI

Oaf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	52,491,314 - 52,509,285 (-)	NCBI		GRCr8
mRatBN7.2	8	43,594,362 - 43,612,334 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	43,594,363 - 43,612,334 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	49,092,153 - 49,110,146 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	47,370,822 - 47,388,815 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	45,238,440 - 45,256,433 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	47,511,718 - 47,529,689 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	47,511,719 - 47,529,689 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	45,980,601 - 45,998,572 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	46,224,861 - 46,242,832 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	46,233,627 - 46,251,598 (-)	NCBI
Celera	8	43,184,283 - 43,202,190 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

Oaf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	21,235,927 - 21,251,182 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	21,235,927 - 21,251,100 (+)	NCBI	ChiLan1.0	ChiLan1.0

OAF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	120,912,578 - 120,931,955 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	122,016,468 - 122,035,657 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	115,045,790 - 115,065,032 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	118,972,578 - 118,991,550 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	118,972,574 - 118,991,170 (+)	Ensembl	panpan1.1		panPan2

OAF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	13,771,208 - 13,798,387 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	13,771,659 - 13,783,190 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	13,826,247 - 13,842,926 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	13,717,188 - 13,733,860 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	13,717,197 - 13,734,236 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	13,854,790 - 13,871,452 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	13,758,765 - 13,785,700 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	13,797,892 - 13,814,560 (-)	NCBI		UU_Cfam_GSD_1.0

Oaf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	102,149,586 - 102,166,267 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	5,070,468 - 5,091,298 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	5,070,995 - 5,087,676 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OAF
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	47,345,165 - 47,362,998 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	47,344,916 - 47,363,768 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	52,413,284 - 52,431,295 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Oaf
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624784	15,571,402 - 15,589,246 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624784	15,571,765 - 15,587,589 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium			6
Low	36	16	54
Below cutoff		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008021209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000000497 ⟹ ENSCSAP00000015564

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	1	111,615,001 - 111,638,431 (+)	Ensembl

RefSeq Acc Id:

XM_008021209 ⟹ XP_008019400

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	111,614,890 - 111,634,309 (+)	NCBI
Vero_WHO_p1.0	NW_023666043	14,425,828 - 14,444,899 (-)	NCBI

Sequence:

show sequence

CAAACTTCTGACACCGCCTGGGCCGCTGACTCCGCGCGGCCGGGAGGGAGGGAGATCGAGGACG
CCGCTCGCACAAAGCCGCGGAGCCGCGGCCCCCTCTCCCCGCCCCCTGCCCGGCCAACGCCGGA
GCGCGGGGAGCAGCCGCGGGCCCTTTAAGGGCCGCGAGGTGCGCGGTCTCTTTAAGGCGGGTCC
TGGTGGTTTCTGTTTTCTGAAGGAAGTGACGGGGGGTGGGATTGAATGAAAAGTGCAAAACACA
GGCTCGCAGCGCCGGAGCCCGGGGCCGCGGAGCCGGGCCGGGGCAGCGTCGTCTCCGCCTCGGG
GCCTCCGGGGGCGCGCTGCCGAGCGCTACCCACGTGCGTTCGTGCCACCTCGCGGGCGACCCCG
CGGCCAAGGCCCCGAGCGGAGCGGCTCCGGAGCGCCCCGAACTAGCCCCCAACTTTGGGCGAAG
TTTGCCTACGCCTCTCCCCGCCCCCACGCGGCGCGCCGGGGCCGCGGACTGCAGTGGCTCCCGG
GGATGCGCCTTCCCGGGGTCCCCCCGGCGCTCCCCGCGCTGTTGCTCCTGCTGCCGCTGCTCGC
GCCGCTGCTGGGAACGGGTGCGCCGGCCGAGCTGCGGGTCCGCGTGCGGCTGCCGGACGGCCAG
GTGACCGAGGAGAGCCTGCAGGCGGACAGCGACGCCGACAGCATCAGCCTCGAGCTGCGCAAGC
CCGACGGCACCCTTGTCTCCTTCACCGCCGACTTCAAGAAGGATGTGAAGATCTTCCGGGCCCT
GATCCTAGGGGAGCTGGAGAAGGGGCAGAGTCAGTTCCAGGCCCTCTGCTTTGTCACCCAGCTG
CAGCACAATGAGATCATCCCCAGTGAGGCCATGGCCAAGCTCCGGCAGAAAAATCCCCGGGCAG
TGCGGCAGGCGGAGGAGGTTCGGGGTCTGGAGCATCTGCACATGGATGTCGCTGTCAACTTCAG
CCAGGGGGCCCTGCTGAGCCCCCATCTCCACAACGTGTGTGCTGAGGCCGTGGATGCCATCTTC
ACCCGCCAGGAGGACGTCCGGTTCTGGCTGGAGCAAGGTGTGGACAGTTCTGTGTTTGAGGCTC
TGCCCAAGGCCTCAGAGCAGGTGGAGCTGCCTCGCTGTGGGCAGGTGGGAGATCGCGGGAAGCC
CTGTGTCTGCCGCTATGGCCTGAGCCTGGCCTGGTACCCCTGCATGCTCAAGTACTGCCACAGC
CGCGACCGGCCCACACCCTACAAGTGTGGCATCCGCAGCTGCCAGAAGAGCTACAGCTTCGACT
TCTACGTGCCCCAGAGGCAGCTGTGTCTCTGGGATGAGGACCCCTAGCCAGGCTAGGGTGGGAG
GGACCTGGAGGGTGGCTGCTCTGGGCCCACTGCTCTTCACCAGCCACTAGAGGGGGTGGCATCC
CCCACCTGAGGCCTTATTTCTCTCCCTCCCCACTCCCCTGGCCCTGGAGCCTGGACCCCTCTGG
CCCCATCACAGATGACTGTGAAAGGGGTGTGGCGTGGCAGGGGGGTCTCATGAAGGCACCCCCA
CTCCCACCCTGTGCCTTCCTTATGGGCAGAGAGGGAGAGAGGGACTCCCCAGGTCTACACCCCT
CCCTCCTGCATCTCCCCTGGAGTGTTCACTTGCAAGCCACCAAAATGTGATGGCCTGTGGTTCT
TCTGCTGAGCTCCTTAAATGTTTAGACCCTGAAAGGAGTCTACAGCTGGACACCCCCCTCCCCA
GACACAACTGCCTTCCCCACGCACACATCTGGAAGGAGCTGGCCCCTCAGTGCCTTCCTACTCC
CCAACATGGGGCTCACCATCCCCAAAGAAGGAGCTGTTGGGGACCCACGATGCAGCCCCTGTCC
CGGATTACAGCGAGTTCTCATTTCTGGCTCTGAGGCTGCCTGTGGGGCGAGTGAAGACCTCCCA
CCGCTGAGACAGACCACAGACCACAGACCACGAGTGCCTTTCCCAGACACCTGGACGTTGCCTC
CCAGAGCAGGCCCCAGCTCTTTCCCTCTCTATACAGAAATATTTTTGTAAGGTTCTGGGGCAGG
GAGGGAGCATGAAGTATGAGGAAAACTTGAATTCCAGATTTTTAATGCAAAGTATTTATCATTT
CTACCAGAAATAAACGTTTTAAGTTTTTATTTGGCAAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008019400	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000015564
	ENSCSAP00000015564.1

RefSeq Acc Id:	XP_008019400 ⟸ XM_008021209
- UniProtKB:	A0A0D9S3X5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000015564 ⟸ ENSCSAT00000000497

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000002480	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000000497.1	UniProtKB/TrEMBL
InterPro	Oaf	UniProtKB/TrEMBL
KEGG Report	csab:103248648	UniProtKB/TrEMBL
NCBI Gene	OAF	ENTREZGENE
PANTHER	OUT AT FIRST PROTEIN HOMOLOG	UniProtKB/TrEMBL
	PTHR13423	UniProtKB/TrEMBL
Pfam	OAF	UniProtKB/TrEMBL
UniProt	A0A0D9S3X5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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