DUSP7 (dual specificity phosphatase 7) - Rat Genome Database

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Gene: DUSP7 (dual specificity phosphatase 7) Chlorocebus sabaeus
Analyze
Symbol: DUSP7
Name: dual specificity phosphatase 7
RGD ID: 18758286
Description: ENCODES a protein that exhibits hydrolase activity (inferred); MAP kinase tyrosine phosphatase activity (inferred); MAP kinase tyrosine/serine/threonine phosphatase activity (inferred); INVOLVED IN negative regulation of MAPK cascade (inferred); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dual specificity protein phosphatase 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,416,262 - 13,423,736 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,416,287 - 13,423,661 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,480,091 - 153,487,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DUSP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,416,262 - 13,423,736 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,416,287 - 13,423,661 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,480,091 - 153,487,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DUSP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,048,919 - 52,056,571 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,048,919 - 52,056,571 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,082,935 - 52,090,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,059,799 - 52,065,329 (-)NCBINCBI36Build 36hg18NCBI36
Build 34352,059,870 - 52,065,269NCBI
Celera352,062,259 - 52,069,785 (-)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef352,146,055 - 52,153,134 (-)NCBIHuRef
CHM1_1352,035,473 - 52,042,994 (-)NCBICHM1_1
T2T-CHM13v2.0352,081,823 - 52,089,474 (-)NCBIT2T-CHM13v2.0
Dusp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,245,831 - 106,252,923 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,245,831 - 106,252,923 (+)EnsemblGRCm39 Ensembl
GRCm389106,368,560 - 106,375,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,368,632 - 106,375,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,270,963 - 106,278,055 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369106,226,733 - 106,233,822 (+)NCBIMGSCv36mm8
MGSCv369107,157,107 - 107,167,680 (+)NCBIMGSCv36mm8
Celera9105,996,040 - 106,003,059 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.46NCBI
Dusp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,888,091 - 115,895,126 (+)NCBIGRCr8
mRatBN7.28107,009,369 - 107,016,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,008,528 - 107,016,404 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,632,332 - 112,639,365 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,831,503 - 110,838,534 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,674,294 - 108,681,327 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,069,095 - 115,076,130 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,069,095 - 115,076,130 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,436,772 - 114,443,807 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,510,358 - 111,515,989 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,530,229 - 111,535,444 (+)NCBI
Celera8106,321,745 - 106,328,777 (+)NCBICelera
Cytogenetic Map8q32NCBI
Dusp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,685,137 - 3,691,933 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,685,137 - 3,691,933 (-)NCBIChiLan1.0ChiLan1.0
DUSP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,043,185 - 52,050,712 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,047,955 - 52,055,470 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,990,115 - 51,997,627 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,219,167 - 53,226,491 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,219,167 - 53,226,491 (-)Ensemblpanpan1.1panPan2
DUSP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,676,077 - 37,682,003 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,657,725 - 37,665,000 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,026,800 - 38,034,077 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,942,727 - 38,034,072 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,390,441 - 37,397,715 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,798,934 - 37,806,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,084,030 - 38,091,307 (+)NCBIUU_Cfam_GSD_1.0
DUSP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,199,409 - 34,206,649 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,199,404 - 34,210,621 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,396,095 - 37,404,952 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Dusp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,858,480 - 5,865,806 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,858,838 - 5,865,657 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 5 51
Low 15 9
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007984456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000011968   ⟹   ENSCSAP00000010022
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2213,416,287 - 13,423,661 (-)Ensembl
RefSeq Acc Id: XM_007984456   ⟹   XP_007982647
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12213,416,262 - 13,423,736 (-)NCBI
Vero_WHO_p1.0NW_023666041153,480,091 - 153,487,666 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007982647 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010022
  ENSCSAP00000010022.1
Reference Protein Sequences
RefSeq Acc Id: XP_007982647   ⟸   XM_007984456
- UniProtKB: A0A0D9RN33 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000010022   ⟸   ENSCSAT00000011968


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013871 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011968.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  MKP UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Rhodanese-like_dom UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/TrEMBL
KEGG Report csab:103227714 UniProtKB/TrEMBL
NCBI Gene DUSP7 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE 7 UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
  Rhodanese UniProtKB/TrEMBL
PIRSF MAPK_Ptase UniProtKB/TrEMBL
PRINTS MAPKPHPHTASE UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
SMART DSPc UniProtKB/TrEMBL
  RHOD UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
  SSF52821 UniProtKB/TrEMBL
UniProt A0A0D9RN33 ENTREZGENE, UniProtKB/TrEMBL