MMP24 (matrix metallopeptidase 24) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MMP24 (matrix metallopeptidase 24) Chlorocebus sabaeus
Analyze
Symbol: MMP24
Name: matrix metallopeptidase 24
RGD ID: 18752616
Description: ENCODES a protein that exhibits cadherin binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN cell-cell adhesion mediated by cadherin (inferred); cell-cell adhesion via plasma-membrane adhesion molecules (inferred); collagen catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); Neoplasm Metastasis (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: matrix metalloproteinase-24
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1256,153,277 - 56,183,026 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl256,152,944 - 56,184,605 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660872,304,079 - 2,334,298 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MMP24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1256,153,277 - 56,183,026 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl256,152,944 - 56,184,605 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660872,304,079 - 2,334,298 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MMP24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382035,226,690 - 35,276,998 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2035,226,690 - 35,276,998 (+)EnsemblGRCh38hg38GRCh38
GRCh372033,814,493 - 33,864,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362033,278,106 - 33,328,218 (+)NCBINCBI36Build 36hg18NCBI36
Build 342033,278,107 - 33,326,511NCBI
Celera2030,583,249 - 30,613,409 (+)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2030,592,010 - 30,642,227 (+)NCBIHuRef
CHM1_12033,715,680 - 33,765,882 (+)NCBICHM1_1
T2T-CHM13v2.02036,947,464 - 36,997,860 (+)NCBIT2T-CHM13v2.0
Mmp24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,617,262 - 155,660,286 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2155,617,262 - 155,660,286 (+)EnsemblGRCm39 Ensembl
GRCm382155,775,342 - 155,818,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,775,342 - 155,818,366 (+)EnsemblGRCm38mm10GRCm38
MGSCv372155,601,080 - 155,644,102 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362155,466,840 - 155,509,807 (+)NCBIMGSCv36mm8
Celera2161,724,940 - 161,750,893 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.26NCBI
Mmp24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,739,226 - 164,783,696 (+)NCBIGRCr8
mRatBN7.23144,279,096 - 144,323,572 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3144,279,096 - 144,323,572 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3148,145,188 - 148,188,968 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,762,468 - 156,806,235 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,501,979 - 154,545,755 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03151,307,309 - 151,355,401 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,310,598 - 151,355,401 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,676,152 - 157,720,612 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3143,019,816 - 143,047,813 (+)NCBICelera
Cytogenetic Map3q42NCBI
Mmp24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,126,929 - 26,154,285 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,128,403 - 26,154,285 (-)NCBIChiLan1.0ChiLan1.0
MMP24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,959,852 - 41,010,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,952,956 - 41,004,532 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02031,554,770 - 31,606,348 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,686,887 - 32,729,403 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,686,887 - 32,729,403 (+)Ensemblpanpan1.1panPan2
MMP24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12424,223,049 - 24,258,082 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2424,232,833 - 24,255,725 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,861,305 - 23,903,980 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,907,564 - 24,950,248 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,907,564 - 24,949,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12424,194,434 - 24,237,113 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02424,276,885 - 24,332,128 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,728,551 - 24,771,226 (+)NCBIUU_Cfam_GSD_1.0
Mmp24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640173,248,000 - 173,270,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365615,478,145 - 5,502,529 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365615,479,107 - 5,501,559 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,588,081 - 38,636,627 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,587,230 - 38,636,628 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Mmp24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248424,131,523 - 4,160,134 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248424,133,323 - 4,159,501 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 10 24
Low 26 20 36
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000008537   ⟹   ENSCSAP00000006681
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl256,152,944 - 56,184,605 (+)Ensembl
RefSeq Acc Id: XM_007963124   ⟹   XP_007961315
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1256,153,282 - 56,183,026 (+)NCBI
Vero_WHO_p1.0NW_0236660872,304,083 - 2,334,298 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007963129   ⟹   XP_007961320
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1256,153,277 - 56,183,026 (+)NCBI
Vero_WHO_p1.0NW_0236660872,304,079 - 2,334,298 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007961315 (Get FASTA)   NCBI Sequence Viewer  
  XP_007961320 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006681
  ENSCSAP00000006681.1
Reference Protein Sequences
RefSeq Acc Id: XP_007961320   ⟸   XM_007963129
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007961315   ⟸   XM_007963124
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RDJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000006681   ⟸   ENSCSAT00000008537


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010450 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008537.1 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A UniProtKB/TrEMBL
  Pept_M10A_metallopeptidase_C UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/TrEMBL
KEGG Report csab:103216031 UniProtKB/TrEMBL
NCBI Gene MMP24 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/TrEMBL
  PTHR10201:SF138 UniProtKB/TrEMBL
Pfam DUF3377 UniProtKB/TrEMBL
  Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF47090 UniProtKB/TrEMBL
  SSF50923 UniProtKB/TrEMBL
UniProt A0A0D9RDJ2 ENTREZGENE, UniProtKB/TrEMBL