HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1) - Rat Genome Database

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Gene: HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1) Chlorocebus sabaeus
Analyze
Symbol: HS3ST1
Name: heparan sulfate-glucosamine 3-sulfotransferase 1
RGD ID: 18750764
Description: ENCODES a protein that exhibits [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity (inferred); sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN glycosaminoglycan biosynthetic process (ortholog); ASSOCIATED WITH arteriosclerosis (ortholog); coronary artery disease (ortholog); genetic disease (ortholog); FOUND IN Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heparan sulfate glucosamine 3-O-sulfotransferase 1; LOC103246543; splicing factor 3B subunit 4-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12738,683,032 - 38,716,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2738,714,570 - 38,715,493 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604785,456,975 - 85,489,159 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
HS3ST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12738,683,032 - 38,716,222 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2738,714,570 - 38,715,493 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604785,456,975 - 85,489,159 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
HS3ST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38411,393,150 - 11,434,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl411,393,150 - 11,429,564 (-)EnsemblGRCh38hg38GRCh38
GRCh37411,394,774 - 11,430,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36411,009,086 - 11,039,635 (-)NCBINCBI36Build 36hg18NCBI36
Build 34411,076,256 - 11,106,806NCBI
Celera411,864,401 - 11,894,954 (-)NCBICelera
Cytogenetic Map4p15.33NCBI
HuRef410,732,784 - 10,763,337 (-)NCBIHuRef
CHM1_1411,398,055 - 11,428,601 (-)NCBICHM1_1
T2T-CHM13v2.0411,369,209 - 11,410,393 (-)NCBIT2T-CHM13v2.0
Hs3st1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39539,771,278 - 39,802,791 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl539,771,278 - 39,912,818 (-)EnsemblGRCm39 Ensembl
GRCm38539,613,935 - 39,645,592 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl539,613,935 - 39,755,475 (-)EnsemblGRCm38mm10GRCm38
MGSCv37540,005,174 - 40,035,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36539,902,184 - 40,043,724 (-)NCBIMGSCv36mm8
Celera537,077,022 - 37,107,666 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map521.14NCBI
Hs3st1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81475,398,101 - 75,429,628 (+)NCBIGRCr8
mRatBN7.21471,185,826 - 71,223,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1471,185,682 - 71,223,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1475,621,414 - 75,651,140 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01476,869,044 - 76,898,770 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01473,309,433 - 73,339,159 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01475,880,410 - 75,881,346 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1475,852,060 - 75,882,693 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01475,872,397 - 75,873,333 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41476,438,219 - 76,439,157 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11476,440,619 - 76,441,546 (+)NCBI
Celera1470,167,035 - 70,167,971 (+)NCBICelera
Cytogenetic Map14q21NCBI
Hs3st1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555491,591,605 - 1,623,681 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555491,591,605 - 1,623,681 (+)NCBIChiLan1.0ChiLan1.0
HS3ST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2311,630,308 - 11,666,199 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1411,838,797 - 11,874,689 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v045,797,803 - 5,829,976 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1411,108,089 - 11,139,043 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl411,108,374 - 11,109,297 (-)Ensemblpanpan1.1panPan2
HS3ST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1368,306,512 - 68,336,879 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha370,831,990 - 70,862,330 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0368,922,300 - 68,952,641 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl368,950,937 - 68,951,854 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1368,330,085 - 68,360,403 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0368,492,806 - 68,523,133 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0368,864,624 - 68,894,997 (+)NCBIUU_Cfam_GSD_1.0
Hs3st1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528561,974,067 - 62,004,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647715,676,178 - 15,706,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647715,676,151 - 15,706,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HS3ST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl87,389,780 - 7,423,869 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.187,389,774 - 7,424,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Hs3st1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475520,035,055 - 20,039,967 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475520,010,126 - 20,039,988 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 6 2 6
Low 30 18 54
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000019789   ⟹   ENSCSAP00000019195
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2738,714,570 - 38,715,493 (+)Ensembl
RefSeq Acc Id: XM_008017890   ⟹   XP_008016081
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12738,683,032 - 38,716,222 (+)NCBI
Vero_WHO_p1.0NW_02366604785,456,975 - 85,489,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008017891   ⟹   XP_008016082
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12738,683,032 - 38,716,222 (+)NCBI
Vero_WHO_p1.0NW_02366604785,457,199 - 85,489,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038008702   ⟹   XP_037864630
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604785,484,798 - 85,489,159 (+)NCBI
RefSeq Acc Id: XM_038008703   ⟹   XP_037864631
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604785,458,974 - 85,489,159 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008016081 (Get FASTA)   NCBI Sequence Viewer  
  XP_008016082 (Get FASTA)   NCBI Sequence Viewer  
  XP_037864630 (Get FASTA)   NCBI Sequence Viewer  
  XP_037864631 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000019195
  ENSCSAP00000019195.1
Reference Protein Sequences
RefSeq Acc Id: XP_008016081   ⟸   XM_008017890
- UniProtKB: A0A0D9SEA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008016082   ⟸   XM_008017891
- UniProtKB: A0A0D9SEA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000019195   ⟸   ENSCSAT00000019789
RefSeq Acc Id: XP_037864631   ⟸   XM_038008703
- UniProtKB: A0A0D9SEA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037864630   ⟸   XM_038008702
- UniProtKB: A0A0D9SEA6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019699 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019789.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro NST/OST UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
KEGG Report csab:103246360 UniProtKB/TrEMBL
NCBI Gene HS3ST1 ENTREZGENE
PANTHER HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 UniProtKB/TrEMBL
  PTHR10605 UniProtKB/TrEMBL
Pfam Sulfotransfer_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9SEA6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 HS3ST1  heparan sulfate-glucosamine 3-sulfotransferase 1  LOC103246543  splicing factor 3B subunit 4-like  Data merged from RGD:18746342 737654 PROVISIONAL