E4F1 (E4F transcription factor 1) - Rat Genome Database

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Gene: E4F1 (E4F transcription factor 1) Chlorocebus sabaeus
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Symbol: E4F1
Name: E4F transcription factor 1
RGD ID: 18748285
Description: ENCODES a protein that exhibits cAMP response element binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA replication (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of mitotic cell cycle, embryonic (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH autosomal dominant polycystic kidney disease (ortholog); developmental and epileptic encephalopathy 1 (ortholog); endometrial carcinoma (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor E4F1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,117,936 - 2,130,787 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,117,479 - 2,130,623 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,928,785 - 28,941,473 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
E4F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,117,936 - 2,130,787 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,117,479 - 2,130,623 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,928,785 - 28,941,473 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
E4F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,223,591 - 2,235,742 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,223,580 - 2,235,742 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,273,592 - 2,285,743 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,213,568 - 2,225,744 (+)NCBINCBI36Build 36hg18NCBI36
Build 34162,213,589 - 2,225,743NCBI
Celera162,487,988 - 2,500,164 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,199,659 - 2,211,835 (+)NCBIHuRef
CHM1_1162,273,496 - 2,285,692 (+)NCBICHM1_1
T2T-CHM13v2.0162,245,946 - 2,258,191 (+)NCBIT2T-CHM13v2.0
E4f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,662,752 - 24,674,366 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,662,752 - 24,689,287 (-)EnsemblGRCm39 Ensembl
GRCm381724,443,778 - 24,455,392 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,443,778 - 24,470,313 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,580,724 - 24,592,256 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,171,379 - 24,182,911 (-)NCBIMGSCv36mm8
Celera1724,958,270 - 24,969,970 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.39NCBI
E4f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,978,975 - 13,999,646 (-)NCBIGRCr8
mRatBN7.21013,471,478 - 13,495,018 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,474,456 - 13,485,974 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,220,916 - 18,232,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,709,761 - 17,721,244 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,208,946 - 13,220,429 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,812,335 - 13,835,847 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,815,293 - 13,826,945 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,629,321 - 13,644,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,701,558 - 13,713,008 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,698,967 - 13,713,008 (-)NCBI
Celera1013,154,954 - 13,166,469 (-)NCBICelera
Cytogenetic Map10q12NCBI
E4f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,030,363 - 15,041,877 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,031,210 - 15,041,437 (-)NCBIChiLan1.0ChiLan1.0
E4F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,724,616 - 2,737,612 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,505,600 - 6,518,512 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,080,205 - 1,092,996 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,323,461 - 2,335,695 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,323,461 - 2,335,695 (+)Ensemblpanpan1.1panPan2
E4F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,743,346 - 38,752,427 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,743,355 - 38,752,403 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,982,727 - 39,991,786 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,051,930 - 39,060,985 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,051,930 - 39,065,832 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,736,943 - 38,745,997 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,709,267 - 38,718,322 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,187,987 - 39,197,042 (-)NCBIUU_Cfam_GSD_1.0
E4f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,879,637 - 104,898,330 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,809,882 - 1,829,157 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,811,131 - 1,829,193 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
E4F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,761,356 - 39,772,262 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,757,679 - 39,773,024 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,408,014 - 42,418,803 (+)NCBISscrofa10.2Sscrofa10.2susScr3
E4f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462482438,146 - 49,019 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462482438,062 - 50,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000008935   ⟹   ENSCSAP00000007067
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl52,117,479 - 2,130,623 (+)Ensembl
RefSeq Acc Id: XM_007982498   ⟹   XP_007980689
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.152,117,938 - 2,130,787 (+)NCBI
Vero_WHO_p1.0NW_02366606828,928,785 - 28,941,469 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007982505   ⟹   XP_007980696
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.152,117,936 - 2,130,787 (+)NCBI
Vero_WHO_p1.0NW_02366606828,928,785 - 28,941,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007982514   ⟹   XP_007980705
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.152,118,336 - 2,130,787 (+)NCBI
Vero_WHO_p1.0NW_02366606828,928,785 - 28,941,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007982518   ⟹   XP_007980709
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.152,118,379 - 2,130,385 (+)NCBI
Vero_WHO_p1.0NW_02366606828,929,287 - 28,941,473 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007980689 (Get FASTA)   NCBI Sequence Viewer  
  XP_007980696 (Get FASTA)   NCBI Sequence Viewer  
  XP_007980705 (Get FASTA)   NCBI Sequence Viewer  
  XP_007980709 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007067
  ENSCSAP00000007067.1
RefSeq Acc Id: XP_007980696   ⟸   XM_007982505
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007980689   ⟸   XM_007982498
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007980705   ⟸   XM_007982514
- Peptide Label: isoform X3
- UniProtKB: A0A0D9REM8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007980709   ⟸   XM_007982518
- Peptide Label: isoform X4
Ensembl Acc Id: ENSCSAP00000007067   ⟸   ENSCSAT00000008935


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010850 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008935.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene E4F1 ENTREZGENE
PANTHER IP01257P-RELATED UniProtKB/TrEMBL
  KRAB AND ZINC FINGER DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
  zf-C2H2_6 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0D9REM8 ENTREZGENE, UniProtKB/TrEMBL