LOC103220608 (sodium-dependent multivitamin transporter) - Rat Genome Database

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Pathways
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Gene: LOC103220608 (sodium-dependent multivitamin transporter) Chlorocebus sabaeus
Analyze
Symbol: LOC103220608 (Ensembl: SLC5A6)
Name: sodium-dependent multivitamin transporter (Ensembl:solute carrier family 5 member 6)
RGD ID: 18746998
Description: ENCODES a protein that exhibits sodium-dependent multivitamin transmembrane transporter activity (ortholog); INVOLVED IN biotin transport (ortholog); pantothenate transmembrane transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); NEURODEGENERATION, INFANTILE-ONSET, BIOTIN-RESPONSIVE (ortholog); PERIPHERAL MOTOR NEUROPATHY, CHILDHOOD-ONSET, BIOTIN-RESPONSIVE (ortholog); FOUND IN basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SLC5A6; solute carrier family 5 member 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,406,221 - 80,415,730 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,407,561 - 80,416,848 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,738,413 - 31,751,070 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103220608
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,406,221 - 80,415,730 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,407,561 - 80,416,848 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,738,413 - 31,751,070 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC5A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38227,199,587 - 27,212,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl227,199,587 - 27,212,958 (-)EnsemblGRCh38hg38GRCh38
GRCh37227,422,455 - 27,435,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36227,275,962 - 27,288,575 (-)NCBINCBI36Build 36hg18NCBI36
Build 34227,334,109 - 27,346,722NCBI
Celera227,268,776 - 27,281,501 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef227,164,164 - 27,176,880 (-)NCBIHuRef
CHM1_1227,352,374 - 27,365,079 (-)NCBICHM1_1
T2T-CHM13v2.0227,241,206 - 27,254,815 (-)NCBIT2T-CHM13v2.0
Slc5a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39531,193,380 - 31,206,268 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl531,193,380 - 31,206,268 (-)EnsemblGRCm39 Ensembl
GRCm38531,036,036 - 31,048,924 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl531,036,036 - 31,048,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv37531,338,409 - 31,351,297 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36531,312,617 - 31,324,830 (-)NCBIMGSCv36mm8
Celera528,507,988 - 28,520,955 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.93NCBI
Slc5a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,039,865 - 31,051,671 (+)NCBIGRCr8
mRatBN7.2625,319,187 - 25,331,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,320,442 - 25,331,712 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx625,621,246 - 25,632,513 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0625,937,114 - 25,948,381 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,416,026 - 25,427,321 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,685,823 - 26,697,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,686,033 - 26,697,116 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,499,460 - 36,512,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,301,630 - 25,312,901 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1625,304,582 - 25,315,853 (+)NCBI
Celera624,811,307 - 24,822,588 (+)NCBICelera
Cytogenetic Map6q14NCBI
SLC5A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,300,360 - 99,317,327 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,304,749 - 99,322,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,199,422 - 27,213,650 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A27,288,726 - 27,302,128 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A27,288,726 - 27,301,896 (-)Ensemblpanpan1.1panPan2
SLC5A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11721,181,916 - 21,194,301 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1721,031,765 - 21,193,112 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1721,073,728 - 21,086,105 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01721,502,873 - 21,515,270 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,351,935 - 21,515,309 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11721,189,666 - 21,202,032 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01721,200,734 - 21,213,100 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01721,247,616 - 21,259,983 (-)NCBIUU_Cfam_GSD_1.0
Slc5a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,489,807 - 65,506,815 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,338,289 - 5,349,758 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,338,119 - 5,349,758 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC5A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3111,922,848 - 111,930,940 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13111,919,298 - 111,930,944 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23118,917,508 - 118,929,193 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 22 35
Low 14 18 25
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007971163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007971164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038006706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000007725   ⟹   ENSCSAP00000005893
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1480,407,561 - 80,416,848 (+)Ensembl
RefSeq Acc Id: XM_038006693   ⟹   XP_037862621
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,631 (-)NCBI
RefSeq Acc Id: XM_038006694   ⟹   XP_037862622
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,846 (-)NCBI
RefSeq Acc Id: XM_038006695   ⟹   XP_037862623
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,751,070 (-)NCBI
RefSeq Acc Id: XM_038006696   ⟹   XP_037862624
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,573 (-)NCBI
RefSeq Acc Id: XM_038006697   ⟹   XP_037862625
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,631 (-)NCBI
RefSeq Acc Id: XM_038006698   ⟹   XP_037862626
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,846 (-)NCBI
RefSeq Acc Id: XM_038006699   ⟹   XP_037862627
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,948 (-)NCBI
RefSeq Acc Id: XM_038006700   ⟹   XP_037862628
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,511 (-)NCBI
RefSeq Acc Id: XM_038006701   ⟹   XP_037862629
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,846 (-)NCBI
RefSeq Acc Id: XM_038006702   ⟹   XP_037862630
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,846 (-)NCBI
RefSeq Acc Id: XM_038006703   ⟹   XP_037862631
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,631 (-)NCBI
RefSeq Acc Id: XM_038006704   ⟹   XP_037862632
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,631 (-)NCBI
RefSeq Acc Id: XM_038006705   ⟹   XP_037862633
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,948 (-)NCBI
RefSeq Acc Id: XM_038006706   ⟹   XP_037862634
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604531,738,413 - 31,750,529 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000005893   ⟸   ENSCSAT00000007725
RefSeq Acc Id: XP_037862623   ⟸   XM_038006695
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862633   ⟸   XM_038006705
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862627   ⟸   XM_038006699
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862622   ⟸   XM_038006694
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862630   ⟸   XM_038006702
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862629   ⟸   XM_038006701
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862626   ⟸   XM_038006698
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862621   ⟸   XM_038006693
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862632   ⟸   XM_038006704
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862631   ⟸   XM_038006703
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862625   ⟸   XM_038006697
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862624   ⟸   XM_038006696
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862634   ⟸   XM_038006706
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037862628   ⟸   XM_038006700
- UniProtKB: A0A0D9RBA4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009645 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007725.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1730.10 UniProtKB/TrEMBL
InterPro Na/Glc_symporter_sf UniProtKB/TrEMBL
  Na/solute_symporter UniProtKB/TrEMBL
  Na/solute_symporter_CS UniProtKB/TrEMBL
KEGG Report csab:103220608 UniProtKB/TrEMBL
NCBI Gene SLC5A6 ENTREZGENE
PANTHER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER UniProtKB/TrEMBL
  SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER UniProtKB/TrEMBL
Pfam SSF UniProtKB/TrEMBL
PROSITE NA_SOLUT_SYMP_1 UniProtKB/TrEMBL
  NA_SOLUT_SYMP_3 UniProtKB/TrEMBL
UniProt A0A0D9RBA4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103220608  sodium-dependent multivitamin transporter  SLC5A6  solute carrier family 5 member 6  Symbol and/or name change 5135510 APPROVED