LVRN (laeverin) - Rat Genome Database

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Gene: LVRN (laeverin) Chlorocebus sabaeus
Analyze
Symbol: LVRN
Name: laeverin
RGD ID: 18740997
Description: ENCODES a protein that exhibits aminopeptidase activity (inferred); metal ion binding (inferred); metalloaminopeptidase activity (inferred); INVOLVED IN peptide catabolic process (inferred); proteolysis (inferred); ASSOCIATED WITH autistic disorder (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aminopeptidase Q
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,243,593 - 19,317,447 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,244,673 - 19,321,208 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,087,464 - 59,166,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LVRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,243,593 - 19,317,447 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,244,673 - 19,321,208 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,087,464 - 59,166,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LVRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,962,475 - 116,027,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,962,454 - 116,027,619 (+)EnsemblGRCh38hg38GRCh38
GRCh375115,298,172 - 115,363,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,326,170 - 115,391,199 (+)NCBINCBI36Build 36hg18NCBI36
Celera5111,246,534 - 111,311,673 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,478,890 - 110,544,021 (+)NCBIHuRef
CHM1_15114,730,769 - 114,796,042 (+)NCBICHM1_1
T2T-CHM13v2.05116,474,883 - 116,539,987 (+)NCBIT2T-CHM13v2.0
Lvrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391846,983,106 - 47,040,313 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1846,983,105 - 47,040,309 (+)EnsemblGRCm39 Ensembl
GRCm381846,848,826 - 46,907,246 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,850,038 - 46,907,242 (+)EnsemblGRCm38mm10GRCm38
MGSCv371847,009,693 - 47,065,100 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361846,975,376 - 47,030,777 (+)NCBIMGSCv36mm8
Celera1848,207,861 - 48,266,898 (+)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.84NCBI
Lvrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,752,788 - 41,861,830 (+)NCBIGRCr8
mRatBN7.21839,606,047 - 39,675,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,607,722 - 39,675,165 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01840,858,828 - 40,957,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,883,224 - 40,953,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,527,597 - 40,601,604 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41841,091,421 - 41,159,543 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1837,857,623 - 37,926,884 (+)NCBICelera
Cytogenetic Map18q11NCBI
Lvrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,761,884 - 35,822,443 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,761,737 - 35,823,550 (+)NCBIChiLan1.0ChiLan1.0
LVRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,206,823 - 111,277,019 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,360,445 - 109,426,347 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,316,857 - 111,381,594 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15117,113,730 - 117,178,853 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5117,113,730 - 117,178,849 (+)Ensemblpanpan1.1panPan2
LVRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,684,244 - 5,750,792 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,684,568 - 5,776,455 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,835,040 - 5,901,425 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,676,282 - 5,742,693 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,676,037 - 5,742,090 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,625,222 - 5,691,572 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,702,629 - 5,769,024 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0115,954,851 - 6,019,641 (+)NCBIUU_Cfam_GSD_1.0
Lvrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,423,731 - 128,506,695 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367421,124,524 - 1,206,008 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,124,286 - 1,207,439 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LVRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2120,117,653 - 120,193,713 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12120,117,584 - 120,193,728 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22125,024,882 - 125,099,597 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Lvrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247335,829,438 - 5,896,796 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247335,828,615 - 5,896,954 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 14 11 20
Below cutoff 22 7 40

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000012868   ⟹   ENSCSAP00000010890
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2319,244,673 - 19,321,208 (+)Ensembl
RefSeq Acc Id: XM_008014194   ⟹   XP_008012385
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12319,243,593 - 19,317,447 (+)NCBI
Vero_WHO_p1.0NW_02366603459,087,464 - 59,166,687 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008012385 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010890.1
Reference Protein Sequences
RefSeq Acc Id: XP_008012385   ⟸   XM_008014194
- UniProtKB: A0A0D9RQK1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000010890   ⟸   ENSCSAT00000012868


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014807 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012868.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.390.10 UniProtKB/TrEMBL
  1.25.50.20 UniProtKB/TrEMBL
  2.60.40.1730 UniProtKB/TrEMBL
  2.60.40.1910 UniProtKB/TrEMBL
InterPro Aminopeptidase_N-like_N UniProtKB/TrEMBL
  Aminopeptidase_N-like_N UniProtKB/TrEMBL
  ERAP1-like_C_dom UniProtKB/TrEMBL
  M1_APN-typ UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/TrEMBL
  Peptidase_M1_dom UniProtKB/TrEMBL
  Peptidase_M4/M1_CTD_sf UniProtKB/TrEMBL
NCBI Gene LVRN ENTREZGENE
PANTHER AMINOPEPTIDASE Q UniProtKB/TrEMBL
  PROTEASE M1 ZINC METALLOPROTEASE UniProtKB/TrEMBL
Pfam ERAP1_C UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/TrEMBL
  Peptidase_M1_N UniProtKB/TrEMBL
PRINTS ALADIPTASE UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF63737 UniProtKB/TrEMBL
UniProt A0A0D9RQK1 ENTREZGENE, UniProtKB/TrEMBL