RNF146 (ring finger protein 146) - Rat Genome Database

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Gene: RNF146 (ring finger protein 146) Chlorocebus sabaeus
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Symbol: RNF146
Name: ring finger protein 146
RGD ID: 18731295
Description: ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH Brain Hypoxia-Ischemia (ortholog); osteochondrodysplasia (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNF146
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11346,441,069 - 46,462,533 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1346,441,741 - 46,442,823 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNF146
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11346,441,069 - 46,462,533 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1346,441,741 - 46,442,823 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RNF146
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,266,682 - 127,288,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,266,726 - 127,288,567 (+)EnsemblGRCh38hg38GRCh38
GRCh376127,587,827 - 127,609,707 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366127,629,713 - 127,651,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 346127,629,712 - 127,651,198NCBI
Celera6128,330,302 - 128,351,791 (+)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,164,466 - 125,186,349 (+)NCBIHuRef
CHM1_16127,852,150 - 127,874,042 (+)NCBICHM1_1
T2T-CHM13v2.06128,455,637 - 128,477,520 (+)NCBIT2T-CHM13v2.0
Rnf146
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391029,220,172 - 29,238,438 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1029,220,172 - 29,238,438 (-)EnsemblGRCm39 Ensembl
GRCm381029,344,176 - 29,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1029,344,176 - 29,362,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv371029,063,982 - 29,082,248 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361029,035,587 - 29,051,858 (-)NCBIMGSCv36mm8
Celera1030,276,585 - 30,294,697 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.6NCBI
Rnf146
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,286,680 - 30,304,367 (+)NCBIGRCr8
mRatBN7.2128,458,864 - 28,475,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,458,887 - 28,475,923 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,260,504 - 28,271,097 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,260,355 - 34,270,948 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0128,461,120 - 28,471,713 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0130,856,923 - 30,873,814 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl130,863,217 - 30,873,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0132,290,907 - 32,307,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,255,138 - 29,265,731 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,258,082 - 29,268,670 (+)NCBI
Celera127,132,709 - 27,143,302 (+)NCBICelera
Cytogenetic Map1p11NCBI
Rnf146
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554368,312,096 - 8,331,648 (+)NCBIChiLan1.0ChiLan1.0
RNF146
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,263,264 - 147,284,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,172,033 - 145,193,592 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06125,057,312 - 125,079,096 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,170,440 - 129,192,602 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6129,190,562 - 129,191,733 (+)Ensemblpanpan1.1panPan2
RNF146
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,988,600 - 66,010,873 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,988,656 - 66,010,881 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha166,794,457 - 66,816,710 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,191,606 - 66,213,917 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,191,010 - 66,213,917 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,121,749 - 66,143,998 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,906,358 - 65,928,595 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,548,694 - 66,570,938 (+)NCBIUU_Cfam_GSD_1.0
Rnf146
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946116,001,734 - 116,023,924 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366392,393,150 - 2,417,982 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366392,394,566 - 2,417,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF146
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl135,909,575 - 35,926,968 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1135,909,789 - 35,927,265 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2139,594,042 - 39,612,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rnf146
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247531,671,614 - 1,706,793 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000019060   ⟹   ENSCSAP00000018485
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1346,441,741 - 46,442,823 (-)Ensembl
RefSeq Acc Id: XM_008007133   ⟹   XP_008005324
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,533 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008007134   ⟹   XP_008005325
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,437 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,602 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008007135   ⟹   XP_008005326
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,459 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008007136   ⟹   XP_008005327
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,533 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008007137   ⟹   XP_008005328
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,437 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,643 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008007138   ⟹   XP_008005329
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,437 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008007139   ⟹   XP_008005330
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11346,441,069 - 46,462,459 (-)NCBI
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038000938   ⟹   XP_037856866
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,552 (-)NCBI
RefSeq Acc Id: XM_038000939   ⟹   XP_037856867
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,602 (-)NCBI
RefSeq Acc Id: XM_038000940   ⟹   XP_037856868
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBI
RefSeq Acc Id: XM_038000941   ⟹   XP_037856869
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604018,718,979 - 18,740,720 (-)NCBI
RefSeq Acc Id: XP_008005324   ⟸   XM_008007133
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005327   ⟸   XM_008007136
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005326   ⟸   XM_008007135
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005330   ⟸   XM_008007139
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005325   ⟸   XM_008007134
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005328   ⟸   XM_008007137
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005329   ⟸   XM_008007138
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000018485   ⟸   ENSCSAT00000019060
RefSeq Acc Id: XP_037856869   ⟸   XM_038000941
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856868   ⟸   XM_038000940
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856867   ⟸   XM_038000939
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856866   ⟸   XM_038000938
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SC96 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018970 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019060.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.30.720.50 UniProtKB/TrEMBL
InterPro RING-HC_RNF146 UniProtKB/TrEMBL
  RNF146 UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
  WWE-dom_subgr UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene RNF146 ENTREZGENE
PANTHER PTHR13417:SF2 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam WWE UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/TrEMBL
PROSITE WWE UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF117839 UniProtKB/TrEMBL
UniProt A0A0D9SC96 ENTREZGENE, UniProtKB/TrEMBL