PPFIA1 (PTPRF interacting protein alpha 1) - Rat Genome Database

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Gene: PPFIA1 (PTPRF interacting protein alpha 1) Chlorocebus sabaeus
Analyze
Symbol: PPFIA1
Name: PTPRF interacting protein alpha 1
RGD ID: 18731062
Description: INVOLVED IN negative regulation of protein localization to plasma membrane (ortholog); negative regulation of stress fiber assembly (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: liprin-alpha-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,184,592 - 4,302,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14,181,681 - 4,301,206 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPFIA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,184,592 - 4,302,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14,181,681 - 4,301,206 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PPFIA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381170,270,690 - 70,384,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1170,270,690 - 70,385,312 (+)EnsemblGRCh38hg38GRCh38
GRCh371170,116,796 - 70,230,502 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,794,471 - 69,908,150 (+)NCBINCBI36Build 36hg18NCBI36
Build 341169,794,470 - 69,902,146NCBI
Celera1167,376,164 - 67,491,698 (+)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1166,374,574 - 66,491,659 (+)NCBIHuRef
CHM1_11169,999,952 - 70,114,102 (+)NCBICHM1_1
T2T-CHM13v2.01170,285,642 - 70,404,818 (+)NCBIT2T-CHM13v2.0
Ppfia1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,030,492 - 144,107,497 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7144,030,495 - 144,107,466 (-)EnsemblGRCm39 Ensembl
GRCm387144,476,755 - 144,553,762 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,476,758 - 144,553,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv377151,662,883 - 151,739,591 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367144,286,155 - 144,363,119 (-)NCBIMGSCv36mm8
Celera7144,239,654 - 144,316,313 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.85NCBI
Ppfia1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,070,608 - 209,147,740 (-)NCBIGRCr8
mRatBN7.21199,641,277 - 199,718,371 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1199,641,277 - 199,717,277 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,024,622 - 208,100,539 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,108,770 - 215,184,563 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01207,782,948 - 207,858,744 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01217,644,259 - 217,721,285 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1217,644,224 - 217,721,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,501,043 - 224,578,551 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01222,200,653 - 222,216,178 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,907,328 - 204,984,408 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,061,640 - 205,139,124 (-)NCBI
Celera1197,200,811 - 197,276,774 (-)NCBICelera
Cytogenetic Map1q42NCBI
Ppfia1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542215,892,566 - 15,998,786 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542215,892,945 - 15,998,786 (-)NCBIChiLan1.0ChiLan1.0
PPFIA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2971,237,861 - 71,355,690 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11172,282,135 - 72,399,879 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01165,368,262 - 65,486,023 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,656,692 - 68,770,842 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1168,657,638 - 68,769,464 (+)Ensemblpanpan1.1panPan2
PPFIA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11847,974,109 - 48,060,331 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1847,975,441 - 48,058,377 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1846,584,324 - 46,669,897 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01848,651,631 - 48,737,237 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1848,651,616 - 48,735,924 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11848,098,783 - 48,184,312 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01847,684,611 - 47,770,122 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01848,430,559 - 48,516,177 (-)NCBIUU_Cfam_GSD_1.0
Ppfia1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,081,185 - 4,167,361 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936599523,507 - 610,065 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936599523,534 - 609,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPFIA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,073,241 - 3,164,235 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,073,236 - 3,165,476 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.221,493,699 - 1,537,667 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ppfia1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476716,905,115 - 17,023,118 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476716,905,196 - 17,024,407 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 25 50
Low 11 20 10
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008015641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008015715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008015793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008015854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008015950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037998890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000007415   ⟹   ENSCSAP00000005597
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl14,181,681 - 4,301,206 (-)Ensembl
RefSeq Acc Id: XM_008015641   ⟹   XP_008013832
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.114,185,340 - 4,302,618 (-)NCBI
Vero_WHO_p1.0NW_023666038101,453,557 - 101,571,662 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008015793   ⟹   XP_008013984
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.114,184,592 - 4,302,677 (-)NCBI
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,662 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008015854   ⟹   XP_008014045
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.114,185,340 - 4,302,677 (-)NCBI
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037998876   ⟹   XP_037854804
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998877   ⟹   XP_037854805
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998878   ⟹   XP_037854806
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998879   ⟹   XP_037854807
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998880   ⟹   XP_037854808
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,455,867 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998881   ⟹   XP_037854809
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998882   ⟹   XP_037854810
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998883   ⟹   XP_037854811
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998886   ⟹   XP_037854814
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998887   ⟹   XP_037854815
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998888   ⟹   XP_037854816
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998889   ⟹   XP_037854817
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,479,145 - 101,571,666 (-)NCBI
RefSeq Acc Id: XM_037998890   ⟹   XP_037854818
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038101,453,538 - 101,571,666 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008013984   ⟸   XM_008015793
- Peptide Label: isoform X13
RefSeq Acc Id: XP_008014045   ⟸   XM_008015854
- Peptide Label: isoform X14
RefSeq Acc Id: XP_008013832   ⟸   XM_008015641
- Peptide Label: isoform X8
- UniProtKB: A0A0D9RAF8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000005597   ⟸   ENSCSAT00000007415
RefSeq Acc Id: XP_037854818   ⟸   XM_037998890
- Peptide Label: isoform X16
RefSeq Acc Id: XP_037854814   ⟸   XM_037998886
- Peptide Label: isoform X10
RefSeq Acc Id: XP_037854809   ⟸   XM_037998881
- Peptide Label: isoform X6
RefSeq Acc Id: XP_037854816   ⟸   XM_037998888
- Peptide Label: isoform X12
RefSeq Acc Id: XP_037854811   ⟸   XM_037998883
- Peptide Label: isoform X9
RefSeq Acc Id: XP_037854815   ⟸   XM_037998887
- Peptide Label: isoform X11
RefSeq Acc Id: XP_037854806   ⟸   XM_037998878
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037854810   ⟸   XM_037998882
- Peptide Label: isoform X7
RefSeq Acc Id: XP_037854805   ⟸   XM_037998877
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037854807   ⟸   XM_037998879
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037854804   ⟸   XM_037998876
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037854808   ⟸   XM_037998880
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037854817   ⟸   XM_037998889
- Peptide Label: isoform X15


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009343 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007415.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
InterPro Liprin UniProtKB/TrEMBL
  Liprin-alpha_SAM_rpt_1 UniProtKB/TrEMBL
  Liprin-alpha_SAM_rpt_2 UniProtKB/TrEMBL
  Liprin-alpha_SAM_rpt_3 UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
KEGG Report csab:103245189 UniProtKB/TrEMBL
NCBI Gene PPFIA1 ENTREZGENE
PANTHER PTHR12587 UniProtKB/TrEMBL
  PTHR12587:SF15 UniProtKB/TrEMBL
Pfam SAM_1 UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
PROSITE SAM_DOMAIN UniProtKB/TrEMBL
SMART SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
UniProt A0A0D9RAF8 ENTREZGENE, UniProtKB/TrEMBL