RO60 (Ro60, Y RNA binding protein) - Rat Genome Database

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Gene: RO60 (Ro60, Y RNA binding protein) Chlorocebus sabaeus
Analyze
Symbol: RO60
Name: Ro60, Y RNA binding protein
RGD ID: 18727124
Description: ENCODES a protein that exhibits U2 snRNA binding (ortholog); INVOLVED IN cellular response to interferon-alpha (ortholog); cilium assembly (ortholog); immune system development (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); Hyperparathyroidism 1 (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60 kDa SS-A/Ro ribonucleoprotein; TROVE domain family member 2; TROVE2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,339,236 - 36,364,066 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2536,340,487 - 36,363,637 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605537,288,148 - 37,312,426 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RO60
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,339,236 - 36,364,066 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2536,340,487 - 36,363,637 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605537,288,148 - 37,312,426 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RO60
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381193,059,612 - 193,091,777 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1193,059,454 - 193,091,777 (+)EnsemblGRCh38hg38GRCh38
GRCh371193,028,742 - 193,060,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,295,376 - 191,327,530 (+)NCBINCBI36Build 36hg18NCBI36
Build 341189,760,820 - 189,786,771NCBI
Celera1166,138,163 - 166,170,512 (+)NCBICelera
Cytogenetic Map1q31.2NCBI
HuRef1164,264,353 - 164,296,702 (+)NCBIHuRef
CHM1_11194,450,271 - 194,482,819 (+)NCBICHM1_1
T2T-CHM13v2.01192,406,634 - 192,438,985 (+)NCBIT2T-CHM13v2.0
Ro60
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,626,528 - 143,652,794 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1143,626,528 - 143,652,806 (-)EnsemblGRCm39 Ensembl
GRCm381143,750,790 - 143,777,063 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,750,790 - 143,777,068 (-)EnsemblGRCm38mm10GRCm38
MGSCv371145,597,920 - 145,624,181 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361145,517,790 - 145,539,196 (-)NCBIMGSCv36mm8
Celera1146,325,813 - 146,352,080 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.54NCBI
Ro60
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81358,049,838 - 58,070,828 (-)NCBIGRCr8
mRatBN7.21355,499,514 - 55,520,504 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1355,499,534 - 55,520,504 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1358,067,723 - 58,089,035 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01359,335,175 - 59,356,177 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01356,620,315 - 56,641,564 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01360,546,892 - 60,567,882 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,546,912 - 60,567,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,535,453 - 65,556,443 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,584,656 - 57,605,648 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11357,600,708 - 57,614,506 (-)NCBI
Celera1355,587,205 - 55,608,219 (-)NCBICelera
Cytogenetic Map13q21NCBI
Ro60
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,468,775 - 30,491,206 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,468,775 - 30,491,206 (+)NCBIChiLan1.0ChiLan1.0
RO60
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2156,701,008 - 56,733,264 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1156,370,687 - 56,397,192 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01168,518,796 - 168,551,137 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,811,822 - 172,844,152 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,811,822 - 172,838,373 (+)Ensemblpanpan1.1panPan2
RO60
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1385,975,824 - 6,004,327 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl385,975,935 - 5,997,945 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha386,072,834 - 6,101,961 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0385,992,433 - 6,021,602 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl385,992,542 - 6,021,612 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1385,991,803 - 6,020,913 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0386,357,378 - 6,386,491 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0386,586,152 - 6,615,302 (-)NCBIUU_Cfam_GSD_1.0
Ro60
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934480,822,410 - 80,855,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366381,304,048 - 1,317,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366381,289,452 - 1,320,522 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RO60
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl10694,445 - 725,346 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.110694,335 - 725,378 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,325,305 - 2,327,942 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ro60
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624814503,271 - 528,807 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624814503,271 - 528,872 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 30 12 60
Low 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011492   ⟹   ENSCSAP00000009561
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2536,340,487 - 36,363,637 (-)Ensembl
RefSeq Acc Id: XM_007989115   ⟹   XP_007987306
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12536,339,884 - 36,363,717 (-)NCBI
Vero_WHO_p1.0NW_02366605537,288,148 - 37,312,093 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007989116   ⟹   XP_007987307
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12536,339,236 - 36,364,066 (-)NCBI
Vero_WHO_p1.0NW_02366605537,288,862 - 37,312,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037985785   ⟹   XP_037841713
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605537,288,862 - 37,311,880 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007987306 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987307 (Get FASTA)   NCBI Sequence Viewer  
  XP_037841713 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009561.1
Reference Protein Sequences
RefSeq Acc Id: XP_007987307   ⟸   XM_007989116
RefSeq Acc Id: XP_007987306   ⟸   XM_007989115
RefSeq Acc Id: ENSCSAP00000009561   ⟸   ENSCSAT00000011492
RefSeq Acc Id: XP_037841713   ⟸   XM_037985785


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011492.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro TROVE2 UniProtKB/TrEMBL
  TROVE_dom UniProtKB/TrEMBL
  TROVE_dom_sf UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103230397 UniProtKB/TrEMBL
NCBI Gene RO60 ENTREZGENE
PANTHER 60 KDA SS-A/RO RIBONUCLEOPROTEIN UniProtKB/TrEMBL
  PTHR14202 UniProtKB/TrEMBL
Pfam TROVE UniProtKB/TrEMBL
PROSITE TROVE UniProtKB/TrEMBL
Superfamily-SCOP SSF140864 UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
UniProt A0A0D9RLS2_CHLSB UniProtKB/TrEMBL