FIGNL1 (fidgetin like 1) - Rat Genome Database

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Gene: FIGNL1 (fidgetin like 1) Chlorocebus sabaeus
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Symbol: FIGNL1
Name: fidgetin like 1
RGD ID: 18723197
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); microtubule severing ATPase activity (inferred); INVOLVED IN cellular response to ionizing radiation (ortholog); male meiotic nuclear division (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); Kidney Neoplasms (ortholog); nicotine dependence (ortholog); FOUND IN cytoplasm (ortholog); nuclear chromosome (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fidgetin-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,351,116 - 8,357,841 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,354,641 - 8,356,665 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606213,923,269 - 13,930,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FIGNL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,351,116 - 8,357,841 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,354,641 - 8,356,665 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606213,923,269 - 13,930,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FIGNL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38750,444,133 - 50,450,350 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl750,444,128 - 50,450,390 (-)EnsemblGRCh38hg38GRCh38
GRCh37750,511,831 - 50,518,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,479,325 - 50,485,582 (-)NCBINCBI36Build 36hg18NCBI36
Build 34750,286,040 - 50,292,257NCBI
Celera750,576,751 - 50,583,008 (-)NCBICelera
Cytogenetic Map7p12.2NCBI
HuRef750,361,796 - 50,368,053 (-)NCBIHuRef
CHM1_1750,514,123 - 50,520,380 (-)NCBICHM1_1
T2T-CHM13v2.0750,605,348 - 50,611,565 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2750,517,901 - 50,524,158 (-)NCBI
Fignl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391111,737,429 - 11,758,962 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1111,737,431 - 11,758,962 (-)EnsemblGRCm39 Ensembl
GRCm381111,800,288 - 11,808,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1111,787,431 - 11,808,962 (-)EnsemblGRCm38mm10GRCm38
MGSCv371111,700,291 - 11,708,965 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361111,700,291 - 11,708,935 (-)NCBIMGSCv36mm8
Celera1112,259,567 - 12,268,241 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.08NCBI
Fignl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,573,090 - 90,595,342 (-)NCBIGRCr8
mRatBN7.21486,368,670 - 86,381,728 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,368,675 - 86,377,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1490,774,815 - 90,783,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01492,019,146 - 92,027,493 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,486,779 - 88,495,126 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,895,902 - 91,904,474 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,895,909 - 91,904,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01491,679,879 - 91,688,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41492,685,445 - 92,693,967 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11492,704,589 - 92,713,112 (-)NCBI
Celera1485,370,247 - 85,378,768 (-)NCBICelera
Cytogenetic Map14q21NCBI
Fignl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554563,588,714 - 3,594,559 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554563,588,190 - 3,594,559 (+)NCBIChiLan1.0ChiLan1.0
FIGNL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,323,098 - 55,329,366 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17103,647,823 - 103,654,089 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0751,080,052 - 51,093,694 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,330,922 - 51,337,201 (-)NCBIpanpan1.1PanPan1.1panPan2
FIGNL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1181,788,063 - 1,792,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl181,788,801 - 1,790,831 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha181,779,396 - 1,786,125 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0181,846,815 - 1,853,537 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl181,846,410 - 1,852,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1181,819,812 - 1,826,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0181,816,264 - 1,822,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0181,953,038 - 1,959,746 (-)NCBIUU_Cfam_GSD_1.0
Fignl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118105,107,576 - 105,111,027 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366861,413,218 - 1,415,248 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366861,412,544 - 1,415,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGNL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9136,484,216 - 136,488,250 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19136,484,217 - 136,488,262 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,064,983 - 150,068,988 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Fignl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247403,739,765 - 3,741,858 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247403,737,482 - 3,748,851 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 10
Low 36 20 50
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000019685   ⟹   ENSCSAP00000019094
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl218,354,641 - 8,356,665 (+)Ensembl
RefSeq Acc Id: XM_007981325   ⟹   XP_007979516
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1218,351,116 - 8,357,841 (+)NCBI
Vero_WHO_p1.0NW_02366606213,923,269 - 13,930,007 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007979516 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000019094.1
RefSeq Acc Id: XP_007979516   ⟸   XM_007981325
- UniProtKB: A0A0D9SE05 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000019094   ⟸   ENSCSAT00000019685


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019595 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019685.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  FIGNL1_ATPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
KEGG Report csab:103226077 UniProtKB/TrEMBL
NCBI Gene FIGNL1 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/TrEMBL
  DYNEIN REGULATORY COMPLEX PROTEIN 11-RELATED UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
PROSITE AAA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9SE05 ENTREZGENE, UniProtKB/TrEMBL