WNT2B (Wnt family member 2B) - Rat Genome Database

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Gene: WNT2B (Wnt family member 2B) Chlorocebus sabaeus
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Symbol: WNT2B
Name: Wnt family member 2B
RGD ID: 18718608
Description: ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN canonical Wnt signaling pathway (ortholog); cellular response to starvation (ortholog); chondrocyte differentiation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Diarrhea 9 (ortholog); endodermal sinus tumor (ortholog); Failure to Thrive (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein Wnt-2b
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12021,116,310 - 21,129,461 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2021,117,415 - 21,123,516 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603823,924,622 - 23,946,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WNT2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12021,116,310 - 21,129,461 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2021,117,415 - 21,123,516 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603823,924,622 - 23,946,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
WNT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381112,466,541 - 112,530,165 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1112,466,541 - 112,530,165 (+)EnsemblGRCh38hg38GRCh38
GRCh371113,009,163 - 113,072,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361112,811,563 - 112,865,428 (+)NCBINCBI36Build 36hg18NCBI36
Build 341112,763,907 - 112,775,947NCBI
Celera1111,240,572 - 111,294,438 (+)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1110,867,409 - 110,923,758 (+)NCBIHuRef
CHM1_11113,124,865 - 113,178,745 (+)NCBICHM1_1
T2T-CHM13v2.01112,479,107 - 112,542,734 (+)NCBIT2T-CHM13v2.0
Wnt2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393104,852,121 - 104,869,025 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3104,852,588 - 104,869,237 (-)EnsemblGRCm39 Ensembl
GRCm383104,944,805 - 104,961,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3104,945,272 - 104,961,921 (-)EnsemblGRCm38mm10GRCm38
MGSCv373104,747,723 - 104,764,627 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363105,072,861 - 105,089,765 (-)NCBIMGSCv36mm8
Celera3107,140,519 - 107,157,750 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.88NCBI
Wnt2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82195,142,573 - 195,156,945 (-)NCBIGRCr8
mRatBN7.22192,454,226 - 192,468,599 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2192,453,824 - 192,470,308 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2200,048,267 - 200,062,643 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02197,920,843 - 197,935,215 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02192,737,793 - 192,752,165 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02207,433,771 - 207,457,094 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2207,440,886 - 207,455,258 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02226,855,010 - 226,869,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42200,218,630 - 200,233,002 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12200,181,392 - 200,189,478 (-)NCBI
Celera2184,920,079 - 184,934,451 (-)NCBICelera
Cytogenetic Map2q34NCBI
Wnt2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543515,948,262 - 15,962,958 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543515,948,262 - 15,962,958 (+)NCBIChiLan1.0ChiLan1.0
WNT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21114,513,844 - 114,526,373 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11113,661,998 - 113,674,496 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01115,119,360 - 115,177,942 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11125,173,906 - 125,230,675 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1125,173,906 - 125,230,675 (-)Ensemblpanpan1.1panPan2
WNT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11763,034,719 - 63,054,369 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1763,035,883 - 63,047,956 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1762,545,377 - 62,561,339 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01764,206,154 - 64,222,116 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1764,210,037 - 64,222,433 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11762,939,810 - 62,955,755 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01762,998,528 - 63,014,476 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01763,758,404 - 63,774,367 (-)NCBIUU_Cfam_GSD_1.0
Wnt2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505816,381,126 - 16,400,255 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366901,079,227 - 1,097,041 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366901,077,538 - 1,094,005 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4107,903,502 - 107,921,118 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14107,906,141 - 107,923,343 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24117,974,503 - 117,990,621 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Wnt2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247728,304,708 - 8,319,349 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247728,305,042 - 8,319,882 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 15 60
Below cutoff 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007977544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCSAT00000016943   ⟹   ENSCSAP00000016438
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2021,117,415 - 21,123,516 (-)Ensembl
RefSeq Acc Id: XM_007977544   ⟹   XP_007975735
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12021,116,310 - 21,129,461 (-)NCBI
Vero_WHO_p1.0NW_02366603823,924,622 - 23,946,252 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007975735 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016438
  ENSCSAP00000016438.1
RefSeq Acc Id: XP_007975735   ⟸   XM_007977544
- UniProtKB: A0A0D9S6E9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000016438   ⟸   ENSCSAT00000016943


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001587 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016943.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2460.20 UniProtKB/TrEMBL
InterPro Wnt UniProtKB/TrEMBL
  Wnt2 UniProtKB/TrEMBL
  Wnt_C UniProtKB/TrEMBL
  Wnt_CS UniProtKB/TrEMBL
NCBI Gene WNT2B ENTREZGENE
PANTHER PROTEIN WNT-2B UniProtKB/TrEMBL
  PTHR12027 UniProtKB/TrEMBL
Pfam wnt UniProtKB/TrEMBL
PRINTS WNT2PROTEIN UniProtKB/TrEMBL
  WNTPROTEIN UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/TrEMBL
SMART WNT1 UniProtKB/TrEMBL
UniProt A0A0D9S6E9 ENTREZGENE, UniProtKB/TrEMBL