LOC103227203 (V-type proton ATPase subunit e 2) - Rat Genome Database

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Gene: LOC103227203 (V-type proton ATPase subunit e 2) Chlorocebus sabaeus
Analyze
Symbol: LOC103227203 (Ensembl: ATP6V0E2)
Name: V-type proton ATPase subunit e 2 (Ensembl:ATPase H+ transporting V0 subunit e2)
RGD ID: 18717289
Description: ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN synaptic vesicle lumen acidification (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN synaptic vesicle membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP6V0E2; ATPase H+ transporting V0 subunit e2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121118,438,435 - 118,446,060 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21118,439,143 - 118,444,214 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607214,398,002 - 14,405,722 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103227203
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121118,438,435 - 118,446,060 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21118,439,143 - 118,444,214 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607214,398,002 - 14,405,722 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ATP6V0E2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387149,872,964 - 149,880,713 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7149,872,968 - 149,891,204 (+)EnsemblGRCh38hg38GRCh38
GRCh377149,570,053 - 149,577,802 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367149,200,990 - 149,208,720 (+)NCBINCBI36Build 36hg18NCBI36
Celera7144,239,268 - 144,246,884 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7143,645,461 - 143,653,226 (+)NCBIHuRef
CHM1_17149,578,636 - 149,586,366 (+)NCBICHM1_1
T2T-CHM13v2.07151,055,071 - 151,062,678 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27148,908,071 - 148,915,657 (+)NCBI
Atp6v0e2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39648,514,503 - 48,518,735 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl648,514,549 - 48,518,735 (+)EnsemblGRCm39 Ensembl
GRCm38648,537,569 - 48,541,801 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl648,537,615 - 48,541,801 (+)EnsemblGRCm38mm10GRCm38
MGSCv37648,487,568 - 48,491,800 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36648,467,201 - 48,471,384 (+)NCBIMGSCv36mm8
Celera649,048,231 - 49,052,496 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map623.52NCBI
Atp6v0e2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8478,815,771 - 78,818,919 (+)NCBIGRCr8
mRatBN7.2477,484,868 - 77,488,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl477,482,226 - 77,488,777 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx482,692,160 - 82,695,320 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0478,467,664 - 78,470,824 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0476,907,939 - 76,911,099 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0478,168,117 - 78,171,265 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,168,117 - 78,171,265 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04142,831,814 - 142,834,962 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4476,621,828 - 76,624,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1476,897,957 - 76,901,106 (+)NCBI
Celera472,422,401 - 72,425,549 (+)NCBICelera
Cytogenetic Map4q24NCBI
Atp6v0e2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554914,929,405 - 4,935,247 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554914,929,405 - 4,935,247 (+)NCBIChiLan1.0ChiLan1.0
ATP6V0E2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26186,428,253 - 186,444,842 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1738,438,514 - 38,448,734 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07141,575,549 - 141,584,844 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17154,047,799 - 154,057,326 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7154,047,799 - 154,057,320 (+)Ensemblpanpan1.1panPan2
ATP6V0E2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11614,642,090 - 14,646,956 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1614,642,200 - 14,646,145 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,250,781 - 15,257,193 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01616,356,998 - 16,363,411 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11614,736,943 - 14,743,356 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01615,317,851 - 15,324,263 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01615,368,517 - 15,374,931 (+)NCBIUU_Cfam_GSD_1.0
Atp6v0e2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,979,066 - 6,985,093 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365275,917,742 - 5,925,299 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365275,918,347 - 5,924,395 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Atp6v0e2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248006,156,364 - 6,164,455 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248006,160,091 - 6,164,426 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 1 60
Low 19
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004938   ⟹   ENSCSAP00000003183
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl21118,439,143 - 118,444,214 (+)Ensembl
RefSeq Acc Id: XM_007983408   ⟹   XP_007981599
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.121118,438,435 - 118,446,060 (+)NCBI
Vero_WHO_p1.0NW_02366607214,398,002 - 14,405,722 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007983410   ⟹   XP_007981601
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.121118,439,022 - 118,444,744 (+)NCBI
Vero_WHO_p1.0NW_02366607214,398,002 - 14,405,717 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007981599 (Get FASTA)   NCBI Sequence Viewer  
  XP_007981601 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003183
  ENSCSAP00000003183.1
Reference Protein Sequences
RefSeq Acc Id: XP_007981599   ⟸   XM_007983408
- UniProtKB: A0A0D9R3J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007981601   ⟸   XM_007983410
- UniProtKB: A0A0D9R3J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000003183   ⟸   ENSCSAT00000004938


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006895 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004938.1 UniProtKB/TrEMBL
InterPro ATPase_V0-cplx_e1/e2_su UniProtKB/TrEMBL
KEGG Report csab:103227203 UniProtKB/TrEMBL
NCBI Gene ATP6V0E2 ENTREZGENE
PANTHER PTHR12263 UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE SUBUNIT E 2 UniProtKB/TrEMBL
Pfam ATP_synt_H UniProtKB/TrEMBL
UniProt A0A0D9R3J4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103227203  V-type proton ATPase subunit e 2  ATP6V0E2  ATPase H+ transporting V0 subunit e2  Symbol and/or name change 5135510 APPROVED