LZIC (leucine zipper and CTNNBIP1 domain containing) - Rat Genome Database

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Gene: LZIC (leucine zipper and CTNNBIP1 domain containing) Chlorocebus sabaeus
Analyze
Symbol: LZIC
Name: leucine zipper and CTNNBIP1 domain containing
RGD ID: 18708461
Description: ENCODES a protein that exhibits beta-catenin binding (inferred); INVOLVED IN response to ionizing radiation (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); chromosome 1p36 deletion syndrome (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein LZIC
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120121,823,745 - 121,832,699 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20121,823,328 - 121,835,152 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605425,751,195 - 25,765,942 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LZIC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120121,823,745 - 121,832,699 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20121,823,328 - 121,835,152 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605425,751,195 - 25,765,942 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LZIC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819,922,118 - 9,943,391 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19,922,113 - 9,943,407 (-)EnsemblGRCh38hg38GRCh38
GRCh3719,982,176 - 10,003,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,912,363 - 9,925,413 (-)NCBINCBI36Build 36hg18NCBI36
Build 3419,924,043 - 9,937,092NCBI
Celera19,100,817 - 9,113,859 (-)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef19,145,513 - 9,158,279 (-)NCBIHuRef
CHM1_119,978,518 - 9,991,643 (-)NCBICHM1_1
T2T-CHM13v2.019,465,032 - 9,486,296 (-)NCBIT2T-CHM13v2.0
Lzic
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,569,642 - 149,581,952 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,569,686 - 149,581,125 (+)EnsemblGRCm39 Ensembl
GRCm384149,485,185 - 149,503,516 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,485,229 - 149,496,668 (+)EnsemblGRCm38mm10GRCm38
MGSCv374148,859,442 - 148,870,777 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364148,329,133 - 148,340,468 (+)NCBIMGSCv36mm8
Celera4151,748,745 - 151,760,219 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map479.53NCBI
Lzic
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,211,359 - 165,224,569 (+)NCBIGRCr8
mRatBN7.25159,928,260 - 159,941,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5159,920,439 - 159,939,685 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5162,644,932 - 162,656,942 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05164,465,039 - 164,477,045 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05164,421,401 - 164,433,407 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05166,430,305 - 166,443,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,430,400 - 166,442,284 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,076,617 - 170,089,776 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,567,412 - 166,579,423 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15166,577,599 - 166,589,610 (+)NCBI
Celera5158,197,959 - 158,209,967 (+)NCBICelera
Cytogenetic Map5q36NCBI
Lzic
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554863,655,812 - 3,666,828 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554863,655,745 - 3,666,828 (+)NCBIChiLan1.0ChiLan1.0
LZIC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21218,275,464 - 218,292,730 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,921,837 - 216,938,351 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018,698,579 - 8,712,867 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.119,930,074 - 9,942,374 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19,928,998 - 9,942,490 (-)Ensemblpanpan1.1panPan2
LZIC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,110,854 - 63,122,488 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,113,191 - 63,122,750 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha563,126,153 - 63,137,847 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0563,337,691 - 63,349,210 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl563,337,345 - 63,349,048 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1563,358,603 - 63,370,114 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,198,129 - 63,209,799 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0563,601,922 - 63,613,447 (-)NCBIUU_Cfam_GSD_1.0
Lzic
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,363,906 - 33,376,857 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366233,851,208 - 3,862,281 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366233,851,208 - 3,862,521 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LZIC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,259,151 - 70,271,955 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,261,447 - 70,271,710 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Lzic
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,591,508 - 2,606,016 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248182,591,415 - 2,605,914 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 1 34
Low 19 26
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000017761   ⟹   ENSCSAP00000017233
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl20121,823,328 - 121,835,152 (+)Ensembl
RefSeq Acc Id: XM_037985066   ⟹   XP_037840994
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605425,751,195 - 25,765,814 (+)NCBI
RefSeq Acc Id: XM_037985067   ⟹   XP_037840995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605425,751,195 - 25,765,942 (+)NCBI
RefSeq Acc Id: XM_037985068   ⟹   XP_037840996
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605425,751,195 - 25,765,814 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037840994 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840995 (Get FASTA)   NCBI Sequence Viewer  
  XP_037840996 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000017233.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000017233   ⟸   ENSCSAT00000017761
RefSeq Acc Id: XP_037840995   ⟸   XM_037985067
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037840994   ⟸   XM_037985066
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037840996   ⟸   XM_037985068
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S8P4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000000773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017761.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.490 UniProtKB/TrEMBL
InterPro ICAT_dom UniProtKB/TrEMBL
  ICAT_sf UniProtKB/TrEMBL
  LZIC UniProtKB/TrEMBL
KEGG Report csab:103225633 UniProtKB/TrEMBL
NCBI Gene LZIC ENTREZGENE
PANTHER PROTEIN LZIC UniProtKB/TrEMBL
  PROTEIN LZIC UniProtKB/TrEMBL
Pfam ICAT UniProtKB/TrEMBL
Superfamily-SCOP SSF81730 UniProtKB/TrEMBL
UniProt A0A0D9S8P4 ENTREZGENE, UniProtKB/TrEMBL