VPS37B (VPS37B subunit of ESCRT-I) - Rat Genome Database

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Gene: VPS37B (VPS37B subunit of ESCRT-I) Chlorocebus sabaeus
Analyze
Symbol: VPS37B
Name: VPS37B subunit of ESCRT-I
RGD ID: 18706683
Description: ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); INVOLVED IN catabolic process (inferred); multivesicular body assembly (inferred); protein targeting to membrane (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (ortholog); ESCRT I complex (ortholog); midbody (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vacuolar protein sorting-associated protein 37B; VPS37B, ESCRT-I subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111118,205,062 - 118,235,844 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11118,205,002 - 118,235,768 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,076,961 - 127,109,352 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
VPS37B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111118,205,062 - 118,235,844 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11118,205,002 - 118,235,768 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,076,961 - 127,109,352 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
VPS37B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812122,865,330 - 122,896,124 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12122,865,330 - 122,896,127 (-)EnsemblGRCh38hg38GRCh38
GRCh3712123,349,877 - 123,380,671 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,915,835 - 121,946,665 (-)NCBINCBI36Build 36hg18NCBI36
Celera12122,941,170 - 122,971,994 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12120,309,887 - 120,340,737 (-)NCBIHuRef
CHM1_112123,318,165 - 123,349,007 (-)NCBICHM1_1
T2T-CHM13v2.012122,860,577 - 122,891,354 (-)NCBIT2T-CHM13v2.0
Vps37b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395124,142,704 - 124,170,323 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5124,142,704 - 124,170,333 (-)EnsemblGRCm39 Ensembl
GRCm385124,004,641 - 124,032,260 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5124,004,641 - 124,032,270 (-)EnsemblGRCm38mm10GRCm38
MGSCv375124,454,650 - 124,482,269 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365124,265,259 - 124,292,878 (-)NCBIMGSCv36mm8
Celera5121,077,230 - 121,104,435 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.32NCBI
Vps37b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81238,220,973 - 38,249,935 (+)NCBIGRCr8
mRatBN7.21232,560,047 - 32,589,015 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,560,047 - 32,589,014 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1233,738,996 - 33,767,751 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01234,350,337 - 34,379,095 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01233,402,228 - 33,430,986 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01237,984,790 - 38,023,369 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1237,984,790 - 38,023,368 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01239,857,153 - 39,894,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,684,358 - 33,713,075 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,547,761 - 33,576,464 (+)NCBI
Celera1234,248,132 - 34,276,582 (+)NCBICelera
Cytogenetic Map12q15NCBI
Vps37b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554825,859,234 - 5,884,665 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554825,879,273 - 5,884,217 (+)NCBIChiLan1.0ChiLan1.0
VPS37B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,959,240 - 130,989,853 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,955,617 - 130,986,230 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012120,469,840 - 120,500,394 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112124,703,077 - 124,733,889 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12124,703,077 - 124,733,889 (-)Ensemblpanpan1.1panPan2
VPS37B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1266,594,981 - 6,621,902 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl266,595,030 - 6,620,408 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,756,791 - 6,783,698 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0266,844,105 - 6,871,052 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl266,844,140 - 6,871,052 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,776,943 - 6,803,891 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,869,672 - 6,896,611 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,823,302 - 6,850,224 (+)NCBIUU_Cfam_GSD_1.0
Vps37b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118157,702,859 - 157,734,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365581,744,914 - 1,776,574 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365581,745,041 - 1,776,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS37B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1429,962,042 - 29,994,646 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11429,963,087 - 29,994,650 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21431,651,931 - 31,683,495 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 38
Low 20 22
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000101   ⟹   ENSCSAP00000015952
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11118,205,002 - 118,235,768 (-)Ensembl
RefSeq Acc Id: XM_008005071   ⟹   XP_008003262
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111118,205,062 - 118,235,844 (-)NCBI
Vero_WHO_p1.0NW_023666037127,076,961 - 127,109,352 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037995709   ⟹   XP_037851637
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037127,102,633 - 127,109,352 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008003262 (Get FASTA)   NCBI Sequence Viewer  
  XP_037851637 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015952
  ENSCSAP00000015952.1
Reference Protein Sequences
RefSeq Acc Id: XP_008003262   ⟸   XM_008005071
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S513 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015952   ⟸   ENSCSAT00000000101
RefSeq Acc Id: XP_037851637   ⟸   XM_037995709
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002083 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000101.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.660 UniProtKB/TrEMBL
InterPro ESCRT_assembly_dom UniProtKB/TrEMBL
  Helix_hairpin_bin_sf UniProtKB/TrEMBL
  Mod_r UniProtKB/TrEMBL
KEGG Report csab:103239317 UniProtKB/TrEMBL
NCBI Gene VPS37B ENTREZGENE
PANTHER VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 UniProtKB/TrEMBL
  VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37B UniProtKB/TrEMBL
Pfam Mod_r UniProtKB/TrEMBL
PROSITE VPS37_C UniProtKB/TrEMBL
Superfamily-SCOP SSF140111 UniProtKB/TrEMBL
UniProt A0A0D9S513 ENTREZGENE, UniProtKB/TrEMBL