SLC25A38 (solute carrier family 25 member 38) - Rat Genome Database

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Gene: SLC25A38 (solute carrier family 25 member 38) Chlorocebus sabaeus
Analyze
Symbol: SLC25A38
Name: solute carrier family 25 member 38
RGD ID: 18693808
Description: ENCODES a protein that exhibits glycine transmembrane transporter activity (inferred); INVOLVED IN erythrocyte differentiation (inferred); glycine import into mitochondrion (inferred); PARTICIPATES IN heme biosynthetic pathway; ASSOCIATED WITH autosomal recessive pyridoxine-refractory sideroblastic anemia 2 (ortholog); genetic disease (ortholog); sideroblastic anemia (ortholog); FOUND IN mitochondrial inner membrane (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial glycine transporter
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11539,051 - 53,170 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1538,881 - 52,775 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660638,764,051 - 8,778,508 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC25A38
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11539,051 - 53,170 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1538,881 - 52,775 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660638,764,051 - 8,778,508 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC25A38
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38339,383,370 - 39,397,351 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl339,383,370 - 39,397,351 (+)EnsemblGRCh38hg38GRCh38
GRCh37339,424,861 - 39,438,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,399,819 - 39,413,823 (+)NCBINCBI36Build 36hg18NCBI36
Celera339,366,402 - 39,380,406 (+)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef339,468,155 - 39,482,157 (+)NCBIHuRef
CHM1_1339,375,927 - 39,389,932 (+)NCBICHM1_1
T2T-CHM13v2.0339,396,296 - 39,410,278 (+)NCBIT2T-CHM13v2.0
Slc25a38
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,939,428 - 119,953,570 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,939,440 - 119,953,570 (+)EnsemblGRCm39 Ensembl
GRCm389120,110,377 - 120,126,093 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,110,374 - 120,124,504 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,019,517 - 120,033,439 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369119,959,097 - 119,973,019 (+)NCBIMGSCv36mm8
Celera9120,580,001 - 120,593,558 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map971.4NCBI
Slc25a38
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88128,713,180 - 128,725,968 (+)NCBIGRCr8
mRatBN7.28119,835,546 - 119,848,334 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,835,634 - 119,848,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8125,416,655 - 125,428,672 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08123,615,691 - 123,627,708 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08121,456,372 - 121,468,146 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,790,348 - 128,802,988 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,790,348 - 128,802,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,991,043 - 128,003,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,084,481 - 125,097,326 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18125,104,217 - 125,117,063 (+)NCBI
Celera8118,981,834 - 118,993,323 (+)NCBICelera
Cytogenetic Map8q32NCBI
Slc25a38
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542029,988,147 - 29,996,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542029,988,147 - 29,996,485 (-)NCBIChiLan1.0ChiLan1.0
SLC25A38
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2239,343,608 - 39,357,136 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1339,348,032 - 39,361,898 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0339,287,934 - 39,301,810 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1339,567,737 - 39,581,966 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl339,567,737 - 39,581,957 (+)Ensemblpanpan1.1panPan2
SLC25A38
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1239,031,984 - 9,045,781 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl239,032,000 - 9,045,788 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,067,493 - 9,079,760 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0239,316,688 - 9,328,967 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl239,316,722 - 9,328,968 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1239,130,095 - 9,142,148 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0239,272,686 - 9,284,973 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0239,266,297 - 9,278,567 (+)NCBIUU_Cfam_GSD_1.0
Slc25a38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,464,571 - 195,482,113 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647328,603,445 - 28,621,355 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647328,602,920 - 28,621,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A38
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1324,030,653 - 24,044,782 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11324,030,571 - 24,043,866 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21326,291,188 - 26,304,483 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Slc25a38
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473078,818,069 - 78,832,091 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20 60
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000012899   ⟹   ENSCSAP00000010918
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1538,881 - 52,775 (-)Ensembl
RefSeq Acc Id: XM_007971704   ⟹   XP_007969895
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11539,051 - 53,170 (-)NCBI
Vero_WHO_p1.0NW_0236660638,764,051 - 8,778,508 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007971705   ⟹   XP_007969896
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11539,051 - 48,644 (-)NCBI
Vero_WHO_p1.0NW_0236660638,764,051 - 8,774,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007971709   ⟹   XP_007969900
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11539,051 - 48,637 (-)NCBI
Vero_WHO_p1.0NW_0236660638,764,051 - 8,774,626 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037988428   ⟹   XP_037844356
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660638,764,051 - 8,778,508 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007969895 (Get FASTA)   NCBI Sequence Viewer  
  XP_007969896 (Get FASTA)   NCBI Sequence Viewer  
  XP_007969900 (Get FASTA)   NCBI Sequence Viewer  
  XP_037844356 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010918
  ENSCSAP00000010918.1
Reference Protein Sequences
RefSeq Acc Id: XP_007969895   ⟸   XM_007971704
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RQM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007969896   ⟸   XM_007971705
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007969900   ⟸   XM_007971709
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCSAP00000010918   ⟸   ENSCSAT00000012899
RefSeq Acc Id: XP_037844356   ⟸   XM_037988428
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014805 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012899.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Hem25/SLC25A38 UniProtKB/TrEMBL
  Mit_carrier UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103221033 UniProtKB/TrEMBL
NCBI Gene SLC25A38 ENTREZGENE
PANTHER MITOCHONDRIAL GLYCINE TRANSPORTER UniProtKB/TrEMBL
  MITOCHONDRIAL GLYCINE TRANSPORTER UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PRINTS MITOCARRIER UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/TrEMBL
UniProt A0A0D9RQM9 ENTREZGENE, UniProtKB/TrEMBL