FBXO3 (F-box protein 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: FBXO3 (F-box protein 3) Chlorocebus sabaeus
Analyze
Symbol: FBXO3
Name: F-box protein 3
RGD ID: 18690462
Description: ENCODES a protein that exhibits ubiquitin ligase-substrate adaptor activity (inferred); INVOLVED IN response to lipopolysaccharide (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,509,950 - 31,543,421 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,509,956 - 31,543,611 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038128,605,747 - 128,639,998 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FBXO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,509,950 - 31,543,421 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,509,956 - 31,543,611 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038128,605,747 - 128,639,998 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FBXO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381133,740,944 - 33,774,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1133,740,939 - 33,774,543 (-)EnsemblGRCh38hg38GRCh38
GRCh371133,762,490 - 33,796,066 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361133,719,066 - 33,752,647 (-)NCBINCBI36Build 36hg18NCBI36
Build 341133,724,868 - 33,752,647NCBI
Celera1133,909,992 - 33,943,582 (-)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1133,458,657 - 33,492,237 (-)NCBIHuRef
CHM1_11133,762,004 - 33,795,579 (-)NCBICHM1_1
T2T-CHM13v2.01133,877,954 - 33,911,529 (-)NCBIT2T-CHM13v2.0
Fbxo3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,858,144 - 103,893,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,858,066 - 103,893,585 (+)EnsemblGRCm39 Ensembl
GRCm382104,027,799 - 104,063,237 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2104,027,721 - 104,063,240 (+)EnsemblGRCm38mm10GRCm38
MGSCv372103,867,956 - 103,903,394 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,828,638 - 103,864,076 (+)NCBIMGSCv36mm8
Celera2105,265,922 - 105,300,910 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.49NCBI
Fbxo3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,872,185 - 110,904,479 (+)NCBIGRCr8
mRatBN7.2390,417,262 - 90,449,557 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl390,417,297 - 90,449,557 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx393,910,311 - 93,942,671 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03102,509,388 - 102,541,746 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03100,339,746 - 100,372,121 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,968,827 - 94,000,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,968,855 - 94,000,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03100,608,746 - 100,640,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4389,446,724 - 89,479,650 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera389,478,591 - 89,510,807 (+)NCBICelera
Cytogenetic Map3q32NCBI
Fbxo3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542212,461,858 - 12,494,553 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542212,462,329 - 12,492,030 (+)NCBIChiLan1.0ChiLan1.0
FBXO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2935,960,609 - 35,994,171 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11135,965,323 - 35,998,916 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,713,147 - 33,746,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,594,854 - 33,628,399 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,594,854 - 33,628,399 (-)Ensemblpanpan1.1panPan2
FBXO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11833,944,441 - 33,974,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1833,944,451 - 33,973,968 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1833,550,035 - 33,580,545 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01834,555,537 - 34,586,084 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1834,555,537 - 34,594,140 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11834,114,297 - 34,144,819 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,707,460 - 33,737,980 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01834,343,094 - 34,373,628 (+)NCBIUU_Cfam_GSD_1.0
Fbxo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494731,075,996 - 31,108,138 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365334,200,757 - 4,234,145 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365334,200,791 - 4,232,929 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl227,146,444 - 27,184,181 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1227,146,407 - 27,183,496 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2229,513,804 - 29,539,556 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Fbxo3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476713,379,895 - 13,410,210 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476713,382,187 - 13,410,143 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 60
Low 20
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000003400   ⟹   ENSCSAP00000001679
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl131,509,956 - 31,543,611 (+)Ensembl
RefSeq Acc Id: XM_008002455   ⟹   XP_008000646
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1131,509,950 - 31,543,421 (+)NCBI
Vero_WHO_p1.0NW_023666038128,605,747 - 128,639,998 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008002464   ⟹   XP_008000655
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1131,509,950 - 31,538,337 (+)NCBI
Vero_WHO_p1.0NW_023666038128,605,747 - 128,637,652 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008000646 (Get FASTA)   NCBI Sequence Viewer  
  XP_008000655 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001679
  ENSCSAP00000001679.1
RefSeq Acc Id: XP_008000646   ⟸   XM_008002455
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QZ90 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008000655   ⟸   XM_008002464
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000001679   ⟸   ENSCSAT00000003400


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005366 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003400.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.60.40.1470 UniProtKB/TrEMBL
  3.40.1580.10 UniProtKB/TrEMBL
InterPro ApaG_domain UniProtKB/TrEMBL
  ApaG_sf UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  Knr4/Smi1-like_dom UniProtKB/TrEMBL
  Knr4/Smi1-like_sf UniProtKB/TrEMBL
KEGG Report csab:103237983 UniProtKB/TrEMBL
NCBI Gene FBXO3 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 3 UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 3 UniProtKB/TrEMBL
Pfam DUF525 UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  SMI1_KNR4 UniProtKB/TrEMBL
PROSITE APAG UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
  SMI1_KNR4 UniProtKB/TrEMBL
Superfamily-SCOP SSF110069 UniProtKB/TrEMBL
  SSF160631 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A0D9QZ90 ENTREZGENE, UniProtKB/TrEMBL