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Gene: DCTPP1 (dCTP pyrophosphatase 1) Chlorocebus sabaeus

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Symbol:

DCTPP1

Name:

dCTP pyrophosphatase 1

RGD ID:

18689453

Description:

ENCODES a protein that exhibits dCTP diphosphatase activity (inferred); hydrolase activity (inferred); identical protein binding (inferred); INVOLVED IN dTTP catabolic process (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DCTPP1 (dCTP pyrophosphatase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Dctpp1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Dctpp1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dctpp1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DCTPP1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DCTPP1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dctpp1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DCTPP1 (dCTP pyrophosphatase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,096,489 - 27,102,778 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,096,212 - 27,102,835 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	2,416,903 - 2,423,222 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dilated cardiomyopathy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dCTP catabolic process (IEA)

DNA protection (IEA)

dTTP catabolic process (ISO)

nucleoside triphosphate catabolic process (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

mitochondrion (IEA,ISO)

nucleoplasm (IEA)

nucleus (IEA,ISO)

Molecular Function

dCTP diphosphatase activity (IEA)

hydrolase activity (IEA)

identical protein binding (IEA)

magnesium ion binding (IEA)

metal ion binding (IEA)

nucleoside triphosphate diphosphatase activity (IEA)

protein binding (ISO)

pyrimidine deoxyribonucleotide binding (IEA)

pyrophosphatase activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

DCTPP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,096,489 - 27,102,778 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,096,212 - 27,102,835 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	2,416,903 - 2,423,222 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

DCTPP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	30,423,615 - 30,430,030 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	30,423,615 - 30,430,030 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	30,434,936 - 30,441,351 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	30,342,520 - 30,348,874 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	29,857,548 - 29,863,885 (+)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	27,997,232 - 28,003,588 (-)	NCBI		HuRef
CHM1_1	16	31,751,466 - 31,757,820 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	30,809,819 - 30,816,234 (-)	NCBI		T2T-CHM13v2.0

Dctpp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	126,856,131 - 126,859,839 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	126,856,131 - 126,859,881 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	127,256,959 - 127,260,667 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	127,256,959 - 127,260,709 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	134,400,473 - 134,404,181 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	127,048,107 - 127,051,815 (-)	NCBI		MGSCv36	mm8
Celera	7	127,105,674 - 127,109,383 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	69.42	NCBI

Dctpp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	191,307,933 - 191,311,326 (-)	NCBI		GRCr8
mRatBN7.2	1	181,877,440 - 181,880,833 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	181,877,437 - 181,880,839 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	190,228,131 - 190,231,512 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	197,414,218 - 197,417,599 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	190,082,593 - 190,085,974 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	198,703,459 - 198,706,852 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	198,703,461 - 198,706,852 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	205,696,305 - 205,699,698 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	186,519,955 - 186,523,348 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	186,669,837 - 186,673,229 (-)	NCBI
Celera	1	179,528,917 - 179,532,300 (-)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

Dctpp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	7,357,204 - 7,360,034 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	7,357,204 - 7,360,034 (-)	NCBI	ChiLan1.0	ChiLan1.0

DCTPP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	33,629,486 - 33,636,121 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	38,430,932 - 38,438,331 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	24,538,023 - 24,545,426 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	30,794,268 - 30,802,207 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	30,794,268 - 30,802,179 (-)	Ensembl	panpan1.1		panPan2

DCTPP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	17,679,681 - 17,683,644 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	17,679,722 - 17,683,570 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	19,253,648 - 19,257,592 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	17,810,663 - 17,814,594 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	17,810,709 - 17,814,520 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	17,610,846 - 17,614,777 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	17,526,330 - 17,530,261 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	17,841,310 - 17,845,272 (+)	NCBI		UU_Cfam_GSD_1.0

Dctpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	124,782,876 - 124,786,371 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	12,879,241 - 12,884,287 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	12,880,745 - 12,884,240 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DCTPP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	17,886,890 - 17,900,557 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	17,896,426 - 17,900,562 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	18,312,086 - 18,316,024 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in DCTPP1
111 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007990051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000004069 ⟹ ENSCSAP00000002331

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	27,096,212 - 27,102,835 (-)	Ensembl

RefSeq Acc Id:

XM_007990051 ⟹ XP_007988242

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	27,096,489 - 27,102,778 (-)	NCBI
Vero_WHO_p1.0	NW_023666068	2,416,903 - 2,423,222 (+)	NCBI

Sequence:

show sequence

CTGGAGGCGGGGCTTCCAGCGTGGCGCGTGGGTTTCCGTGCAGTGGCGGCTGCAGCGGGTGGGC
GGCATGTCTGTGGCCGGTGGGGAGATTCGTGGAGACACGGTGGGAGAGGACACTGCTGCTCCCG
GCCGGTTCAGCTTCAGCCCGGAGCCCACGCTCGAGGACATTCGCCGCCTCCATGCCGAATTTGC
TGCAGAACGAGACTGGGAACAGTTCCATCAGCCTCGGAACCTCCTCCTGGCCTTGGTCGGGGAA
GTGGGGGAGCTCGCAGAACTCTTTCAGTGGAAAACCGATGGGGAACCTGGCCCCCAAGGCTGGT
CCCCCAGGGAACGGTTAGCCCTTCAAGAGGAGCTTAGTGACGTCCTCATCTACCTAGTGGCATT
AGCAGCCCGCTGCCGTGTGGATCTGCCGCTAGCAGTGCTCTCCAAAATGGACATCAACCGGCGA
CGCTACCCAGCCCATCTGGCCCGCAGCTCTTCCCGCAAGTATACAGAATTGCCCCATGGTGCCA
TCTCTGAAGACCAGGCTGTGGGGCCTGCGGACCTTCCCTGTGACTCCACGGGCCAGACCTCAAC
CTAGAAAGGTGGCCACAGGACTTGCAACTCAGGGTGGTGTCTGAAGAGCAGAGGGTGGCCTGGC
CCTGGAGCCATTTTCCAGTCTTTTCCAAATAGATCATGGGCCTGAGGTCTCCACTTCTTGAGGT
CTGAGGCCCAGCAACCTCTAGAAGGTAGCCTCCTGGTGTTTGCTCTCCCAGTAAAATGGTTTTG
GGCAATAACTTCTAGATTCTTCCTGGATGGCCAGGGAGGCTCTCTGTCTCTGCAGGTGATGGCG
AGGGGACCAGGGGTGCCTCTGAGCCCCATTCTCGTGTTTCCCTGTTTTTACCTTTTGCCTGCAG
GGCAGAGAGATCTGGTTTTTAGCAAATTCCCAGTAGGATGTCATGTAAGCTCCTTCCCCCTCCT
TTTAGAGATTGGAGGCTATAAGAGTCCAGATGCTGGAGCTAGGCTGTCTGGGTTCAGATGCCAT
CTTTGACACTTGCAAGCTGGATGACATTACTCAAATTAATCTTTGTGCACTTCAGCTTCCTTGT
CTATAAAATAAAAATAATAGTACCTGCCCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007988242	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002331
	ENSCSAP00000002331.1

RefSeq Acc Id:	XP_007988242 ⟸ XM_007990051
- UniProtKB:	A0A0D9R142 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000002331 ⟸ ENSCSAT00000004069

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006031	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004069.1	UniProtKB/TrEMBL
Gene3D-CATH	MazG-like	UniProtKB/TrEMBL
InterPro	dCTP_Pyrophosphatase	UniProtKB/TrEMBL
	DCTPP	UniProtKB/TrEMBL
KEGG Report	csab:103230924	UniProtKB/TrEMBL
NCBI Gene	DCTPP1	ENTREZGENE
PANTHER	DCTP PYROPHOSPHATASE 1	UniProtKB/TrEMBL
	DCTP PYROPHOSPHATASE 1	UniProtKB/TrEMBL
Pfam	MazG-like	UniProtKB/TrEMBL
Superfamily-SCOP	all-alpha NTP pyrophosphatases	UniProtKB/TrEMBL
UniProt	A0A0D9R142	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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