WDR24 (WD repeat domain 24) - Rat Genome Database

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Gene: WDR24 (WD repeat domain 24) Chlorocebus sabaeus
Analyze
Symbol: WDR24
Name: WD repeat domain 24
RGD ID: 18686182
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to nutrient levels (inferred); positive regulation of macroautophagy (inferred); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 16 (ortholog); cerebellar ataxia type 48 (ortholog); epilepsy (ortholog); FOUND IN cytosol (inferred); GATOR2 complex (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GATOR complex protein WDR24; WD repeat-containing protein 24
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15604,412 - 610,665 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5604,545 - 610,359 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,526,690 - 30,532,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WDR24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15604,412 - 610,665 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5604,545 - 610,359 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,526,690 - 30,532,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
WDR24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816684,622 - 690,398 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16684,622 - 690,444 (-)EnsemblGRCh38hg38GRCh38
GRCh3716734,622 - 740,398 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616674,703 - 680,401 (-)NCBINCBI36Build 36hg18NCBI36
Build 3416674,702 - 680,401NCBI
Celera16934,859 - 940,557 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16656,579 - 662,277 (-)NCBIHuRef
CHM1_116734,676 - 740,374 (-)NCBICHM1_1
T2T-CHM13v2.016688,697 - 694,473 (-)NCBIT2T-CHM13v2.0
Wdr24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,042,601 - 26,047,704 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,042,601 - 26,047,704 (+)EnsemblGRCm39 Ensembl
GRCm381725,823,627 - 25,828,730 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,823,627 - 25,828,730 (+)EnsemblGRCm38mm10GRCm38
MGSCv371725,960,572 - 25,965,675 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,551,316 - 25,556,324 (+)NCBIMGSCv36mm8
Celera1726,356,450 - 26,361,553 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.92NCBI
Wdr24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,346,835 - 15,353,384 (+)NCBIGRCr8
mRatBN7.21014,844,089 - 14,848,871 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,843,728 - 14,848,864 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,583,098 - 19,587,880 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,071,974 - 19,076,756 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,572,254 - 14,577,036 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,191,078 - 15,195,860 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,191,078 - 15,195,860 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,004,021 - 15,008,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,089,474 - 15,094,256 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,089,637 - 15,094,113 (+)NCBI
Celera1014,513,031 - 14,517,813 (+)NCBICelera
Cytogenetic Map10q12NCBI
Wdr24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,513,448 - 16,519,296 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,513,074 - 16,519,296 (+)NCBIChiLan1.0ChiLan1.0
WDR24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218925,834 - 931,678 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,709,701 - 4,715,567 (-)NCBINHGRI_mPanPan1
PanPan1.116699,007 - 704,844 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16699,142 - 704,869 (-)Ensemblpanpan1.1panPan2
WDR24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,887,968 - 39,891,633 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,887,667 - 39,891,588 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,151,453 - 41,155,872 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,229,968 - 40,234,399 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,229,769 - 40,234,385 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,918,559 - 39,922,977 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,878,768 - 39,883,172 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,357,890 - 40,362,310 (+)NCBIUU_Cfam_GSD_1.0
Wdr24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,224,001 - 112,229,124 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501321,924 - 327,253 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501321,877 - 326,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,085,463 - 41,090,610 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,085,415 - 41,090,628 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,387,148 - 41,392,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Wdr24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,496,029 - 1,501,800 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,496,029 - 1,501,822 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 19 20
Low 17 20 40
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007980567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000010349   ⟹   ENSCSAP00000008444
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl5604,545 - 610,359 (-)Ensembl
RefSeq Acc Id: XM_007980567   ⟹   XP_007978758
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.15604,412 - 610,665 (-)NCBI
Vero_WHO_p1.0NW_02366606830,526,690 - 30,532,746 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007978758 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008444
  ENSCSAP00000008444.1
Reference Protein Sequences
RefSeq Acc Id: XP_007978758   ⟸   XM_007980567
- UniProtKB: A0A0D9RIK5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000008444   ⟸   ENSCSAT00000010349


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012255 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010349.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  WDR24 UniProtKB/TrEMBL
KEGG Report csab:103225607 UniProtKB/TrEMBL
NCBI Gene WDR24 ENTREZGENE
PANTHER GATOR COMPLEX PROTEIN WDR24 UniProtKB/TrEMBL
  PTHR46200 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9RIK5 ENTREZGENE, UniProtKB/TrEMBL