RAB11B (RAB11B, member RAS oncogene family)

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Gene: RAB11B (RAB11B, member RAS oncogene family) Chlorocebus sabaeus

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Symbol:

RAB11B

Name:

RAB11B, member RAS oncogene family

RGD ID:

18682794

Description:

ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN endocytosis (ortholog); regulation of presynaptic dense core granule exocytosis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cytoplasmic vesicle (ortholog); synaptic vesicle (ortholog); synaptic vesicle membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras-related protein Rab-11B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	7,743,130 - 7,757,237 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	7,743,361 - 7,757,305 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	12,504,898 - 12,519,218 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

human immunodeficiency virus infectious disease (ISO)

mucolipidosis type IV (ISO)

Neurodevelopmental Disorder with Ataxic Gait, Absent Speech, and Decreased Cortical White Matter (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amyloid-beta clearance by transcytosis (IEA)

cellular response to acidic pH (IEA)

constitutive secretory pathway (IEA)

endocytic recycling (IEA)

endocytosis (ISO)

establishment of protein localization to membrane (IEA)

insulin secretion involved in cellular response to glucose stimulus (IEA)

melanosome transport (IEA)

receptor recycling (IEA)

regulated exocytosis (IEA)

regulation of endocytic recycling (IEA)

regulation of monoatomic anion transport (IEA)

regulation of presynaptic dense core granule exocytosis (ISO)

regulation of protein localization to cell surface (IEA)

transferrin transport (IEA)

Cellular Component

cytoplasm (IEA)

cytoplasmic vesicle (ISO)

Golgi apparatus (IEA)

phagocytic vesicle (IEA)

recycling endosome (IEA)

recycling endosome membrane (IEA)

synaptic vesicle (ISO)

synaptic vesicle membrane (ISO)

Molecular Function

GDP binding (IEA)

GTP binding (IEA)

GTPase activity (IEA)

myosin V binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RAB11B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	7,743,130 - 7,757,237 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	7,743,361 - 7,757,305 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	12,504,898 - 12,519,218 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

RAB11B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	8,390,360 - 8,404,434 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	8,389,981 - 8,404,434 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	8,455,244 - 8,469,318 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	8,361,296 - 8,374,479 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	8,361,295 - 8,374,479	NCBI
Celera	19	8,311,860 - 8,325,986 (+)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	8,108,703 - 8,123,515 (+)	NCBI		HuRef
CHM1_1	19	8,454,661 - 8,468,772 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	8,376,828 - 8,390,915 (+)	NCBI		T2T-CHM13v2.0

Rab11b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	33,961,458 - 33,979,460 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	33,961,458 - 33,979,504 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	33,742,484 - 33,760,486 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	33,742,484 - 33,760,530 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	33,879,429 - 33,897,431 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	33,353,479 - 33,367,177 (-)	NCBI		MGSCv36	mm8
Celera	17	36,499,813 - 36,517,815 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	17.98	NCBI

Rab11b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	15,223,613 - 15,236,754 (-)	NCBI		GRCr8
mRatBN7.2	7	14,521,448 - 14,534,589 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	14,521,368 - 14,534,593 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	17,530,010 - 17,543,161 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	19,395,243 - 19,408,385 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	17,275,599 - 17,288,744 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	18,598,991 - 18,612,132 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	18,598,880 - 18,612,147 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	18,776,591 - 18,789,732 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	16,232,840 - 16,246,007 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	16,232,842 - 16,246,007 (-)	NCBI
Celera	7	13,420,039 - 13,433,194 (-)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

Rab11b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955563	1,008,769 - 1,017,315 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955563	1,008,267 - 1,017,315 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAB11B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	13,058,006 - 13,072,108 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	12,174,697 - 12,188,777 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	7,676,095 - 7,690,177 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	8,526,294 - 8,540,147 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

RAB11B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	52,955,949 - 52,966,279 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	52,956,529 - 52,965,383 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	52,757,255 - 52,768,977 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	53,484,088 - 53,495,852 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	53,484,656 - 53,498,327 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	52,686,120 - 52,697,840 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	53,131,752 - 53,143,468 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	53,363,591 - 53,375,312 (+)	NCBI		UU_Cfam_GSD_1.0

Rab11b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	212,624,348 - 212,636,058 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	5,198,394 - 5,214,603 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	5,198,659 - 5,210,430 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB11B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	70,884,462 - 70,896,172 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	70,884,457 - 70,896,169 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	71,251,151 - 71,262,863 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Rab11b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	1,165,327 - 1,174,417 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	1,165,877 - 1,174,306 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007995124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000006076 ⟹ ENSCSAP00000004286

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	6	7,743,361 - 7,757,305 (+)	Ensembl

RefSeq Acc Id:

XM_007995124 ⟹ XP_007993315

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	7,743,130 - 7,757,237 (+)	NCBI
Vero_WHO_p1.0	NW_023666074	12,504,898 - 12,519,218 (-)	NCBI

Sequence:

show sequence

ATTCCTTCCGCCTTTCTCCAGGACACCTAGGGCGAGGAGGGTGGATACCAAGCGGCGCGCACCC
TCAGAGCACTACTTCCATCTCTGATTGGCTCCGCTAGGTGCCAGTCGCTACTCCACCCGGCGCT
GATAGGCCATTCAACGGCCGTTCTGCGCGGCGCCGGCTCCGCCCCCGTCGGGTGTTTGTGGTGG
GGCTGCGGAGTCGCCGATCCCGCCGGAAGCGCCAGGACAATGGGGACCCGGGACGACGAGTACG
ACTACCTATTCAAAGTGGTGCTCATCGGGGACTCGGGCGTGGGCAAGAGCAACCTGCTGTCGCG
CTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGC
AGCATCCAGGTGGACGGCAAGACCATCAAGGCGCAGATCTGGGACACCGCCGGCCAGGAGCGCT
ACCGCGCCATCACCTCCGCGTACTACCGAGGTGCAGTGGGCGCCCTGCTGGTGTATGACATCGC
CAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTTCGGGACCACGCAGACAGC
AACATTGTCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCATCTGCGGGCCGTGCCCACTG
ACGAGGCCCGCGCCTTTGCGGAAAAGAACAACTTGTCCTTCATCGAGACCTCGGCCTTGGATTC
CACCAACGTAGAGGAAGCATTCAAGAACATCCTCACAGAGATCTACCGCATCGTGTCACAGAAA
CAGATTGCAGACCGCGCTGCCCACGACGAGTCCCCGGGGAACAACGTGGTGGACATCAGCGTGC
CGCCCACCACGGACGGACAGAAGCCCAACAAGCTGCAGTGCTGCCAGAACCTGTGACCCCCGCG
CCTCCGCCCAGCGTGCGTGCACGTCCTCTGCCCGCCCCCGCCACGGTGTCCTCCGGCCCCTCCC
TGCTGTCCCTCTGTGGCCGGCTCGCTCCAGCCCTCCCAGTGAGCTCTGCACGGCCCGGCCGGGG
CCCAGGAAGGACAGGAGCCAGTGCTACCCCCGTCCTGCCCGGGGAAAAGCTAGAAGCCCCGGTT
TGCTGCACCCATGAAACTCGGGTCCCCGCCGACATCTTGGCGGGGTTGCGGGGGGGACGGCAGG
ATGGACCGGGCTGGCCAGAGGTGAGGAGGATGGGCGGACGGTGCCGCCTTCTCCCCTTTTCCTC
GGCCGACTCCAGGGAGCGATTGCCTCCCTCCCTCTGTGGCTGGGTGGCCCAGCCAGCCCGTCGT
CCCCACCCAGAACCCTGCTCTGGGCCAAAGCCCGAAGAACCAGGCAGTGGGGACCGGGGCAGGC
GGACCCCCCGGGCTCTTAGCGCCCACCCGCTCCTTAGCGCACAGCAGCTCGCACAGGCCTCTCA
CCTCTGCCTGTTGATCGATGCAGGGAGAAGCCCGTCCCCACCTCCCCTGTCCCCTCTCCTCTCC
CTACTCCCCTCTCCTGCACGCAGCGCGCCCGCCCTCTCGGCCCTCCCTGTCCCCCTCCTCTGTC
TCGTCTCCCCATCTGGTCTGGAACCTGTTTGCAAGTGAAGCAATATTTCCGTGTTTTGTATATA
CAACCGCTCTTGTAGCCTTTGGTTTTTGTTAATGTAGAGAAACACAGATTCTTTATACACTTTG
TAAGATTTACGCCAAACCCCAGCTCTCGATCTCTTCTTCTCCCTGTGGCCCCTGCACTGTTGCC
CCGTTCCCGTCACCCTGCCCATTACTGAAATGTATAATCTGACTTCCTGTACAGAAACCTGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007993315	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000004286
	ENSCSAP00000004286.1

RefSeq Acc Id:	XP_007993315 ⟸ XM_007995124
- UniProtKB:	A0A0D9R6P7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000004286 ⟸ ENSCSAT00000006076

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000008024	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000006076.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Rab_GTPases_membrane_traffic	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
KEGG Report	csab:103233840	UniProtKB/TrEMBL
NCBI Gene	RAB11B	ENTREZGENE
PANTHER	DRAB11-RELATED	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB-11B	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0D9R6P7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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