COQ8B (coenzyme Q8B) - Rat Genome Database

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Gene: COQ8B (coenzyme Q8B) Chlorocebus sabaeus
Analyze
Symbol: COQ8B
Name: coenzyme Q8B
RGD ID: 18680471
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN cerebellar Purkinje cell layer morphogenesis (ortholog); ASSOCIATED WITH Carpenter Syndrome 2 (ortholog); congenital hypoplastic anemia (ortholog); craniosynostosis (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aarF domain containing kinase 4; aarF domain-containing protein kinase 4; ADCK4; atypical kinase COQ8B, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,142,435 - 35,168,881 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl635,143,043 - 35,166,216 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607313,278,901 - 13,306,489 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
COQ8B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,142,435 - 35,168,881 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl635,143,043 - 35,166,216 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607313,278,901 - 13,306,489 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
COQ8B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,691,530 - 40,716,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,691,514 - 40,725,784 (-)EnsemblGRCh38hg38GRCh38
GRCh371941,197,435 - 41,222,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,889,274 - 45,914,440 (-)NCBINCBI36Build 36hg18NCBI36
Build 341945,889,273 - 45,914,440NCBI
Celera1937,997,846 - 38,023,215 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,630,742 - 37,656,159 (-)NCBIHuRef
CHM1_11941,197,089 - 41,222,469 (-)NCBICHM1_1
T2T-CHM13v2.01943,512,196 - 43,537,578 (-)NCBIT2T-CHM13v2.0
Coq8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39726,928,112 - 26,957,374 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl726,932,448 - 26,957,375 (+)EnsemblGRCm39 Ensembl
GRCm38727,228,676 - 27,257,949 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,233,023 - 27,257,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37728,018,032 - 28,042,968 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36726,942,749 - 26,966,705 (+)NCBIMGSCv36mm8
Celera721,809,930 - 21,834,862 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map715.85NCBI
Coq8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,653,241 - 91,676,822 (+)NCBIGRCr8
mRatBN7.2182,525,578 - 82,549,182 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,526,568 - 82,549,180 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx187,929,496 - 87,951,832 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,416,219 - 96,438,751 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,685,363 - 89,707,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,043,487 - 84,067,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,044,551 - 84,067,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,255,491 - 85,278,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,310,541 - 82,332,822 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,388,651 - 82,410,933 (+)NCBI
Celera176,939,527 - 76,961,663 (+)NCBICelera
Cytogenetic Map1q21NCBI
Coq8b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578615,381 - 635,488 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955578615,820 - 635,488 (+)NCBIChiLan1.0ChiLan1.0
COQ8B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,949,937 - 46,975,711 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11948,820,920 - 48,846,342 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01937,735,725 - 37,761,160 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,242,576 - 46,267,538 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,242,576 - 46,267,503 (-)Ensemblpanpan1.1panPan2
COQ8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,056,369 - 113,075,773 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,057,141 - 113,102,074 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,459,635 - 112,478,211 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,655,919 - 113,674,506 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,655,984 - 113,701,252 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,215,422 - 113,233,994 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,847,105 - 112,865,824 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,841,403 - 113,859,981 (+)NCBIUU_Cfam_GSD_1.0
Coq8b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,561,095 - 14,578,287 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366612,989,162 - 3,006,289 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366612,989,164 - 3,008,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COQ8B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,919,520 - 48,938,111 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,919,000 - 48,939,194 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,613,600 - 44,623,728 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Coq8b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624925622,811 - 655,948 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624925623,656 - 655,940 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 1 43
Low 19 17
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007996853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007996862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037991718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000001696   ⟹   ENSCSAP00000000038
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl635,143,043 - 35,166,216 (-)Ensembl
RefSeq Acc Id: XM_037991711   ⟹   XP_037847639
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,306,489 (-)NCBI
RefSeq Acc Id: XM_037991712   ⟹   XP_037847640
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,303,901 (-)NCBI
RefSeq Acc Id: XM_037991713   ⟹   XP_037847641
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,304,348 (-)NCBI
RefSeq Acc Id: XM_037991714   ⟹   XP_037847642
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,303,427 (-)NCBI
RefSeq Acc Id: XM_037991715   ⟹   XP_037847643
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,303,409 (-)NCBI
RefSeq Acc Id: XM_037991716   ⟹   XP_037847644
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,303,392 (-)NCBI
RefSeq Acc Id: XM_037991717   ⟹   XP_037847645
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,303,272 (-)NCBI
RefSeq Acc Id: XM_037991718   ⟹   XP_037847646
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607313,278,901 - 13,303,981 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000000038   ⟸   ENSCSAT00000001696
RefSeq Acc Id: XP_037847639   ⟸   XM_037991711
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037847641   ⟸   XM_037991713
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037847646   ⟸   XM_037991718
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QUJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037847640   ⟸   XM_037991712
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037847642   ⟸   XM_037991714
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037847643   ⟸   XM_037991715
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QUJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037847644   ⟸   XM_037991716
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QUJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037847645   ⟸   XM_037991717
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QUJ9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003665 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001696.1 UniProtKB/TrEMBL
InterPro ADCK3_UbiB UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  UbiB_dom UniProtKB/TrEMBL
NCBI Gene COQ8B ENTREZGENE
PANTHER PTHR43851 UniProtKB/TrEMBL
  PTHR43851:SF4 UniProtKB/TrEMBL
Pfam ABC1 UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9QUJ9 ENTREZGENE, UniProtKB/TrEMBL