LOC103239735 (inactive phospholipid phosphatase 7)

Gene: LOC103239735 (inactive phospholipid phosphatase 7) Chlorocebus sabaeus

Analyze

Symbol:

LOC103239735 (Ensembl: PLPP7)

Name:

inactive phospholipid phosphatase 7 (Ensembl:phospholipid phosphatase 7 (inactive))

RGD ID:

18678215

Description:

ENCODES a protein that exhibits lipid phosphatase activity (ortholog); INVOLVED IN negative regulation of myotube differentiation (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2K (ortholog); genetic disease (ortholog); primary coenzyme Q10 deficiency 7 (ortholog); FOUND IN membrane (inferred); nuclear envelope (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

phospholipid phosphatase 7 (inactive); PLPP7; probable lipid phosphate phosphatase PPAPDC3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	6,832,015 - 6,850,313 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	6,832,283 - 6,849,598 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	8,658,852 - 8,709,428 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive limb-girdle muscular dystrophy type 2K (ISO)

genetic disease (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of myotube differentiation (IEA,ISO)

Cellular Component

membrane (IEA)

nuclear envelope (IEA)

Molecular Function

lipid phosphatase activity (ISO)

sphingosine-1-phosphate phosphatase activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

LOC103239735
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	6,832,015 - 6,850,313 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	6,832,283 - 6,849,598 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	8,658,852 - 8,709,428 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PLPP7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	131,289,723 - 131,309,261 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	131,289,459 - 131,359,022 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	134,165,110 - 134,184,648 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	133,154,945 - 133,174,468 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	131,194,677 - 131,214,201	NCBI
Celera	9	104,704,143 - 104,723,704 (+)	NCBI		Celera
Cytogenetic Map	9	q34.13	NCBI
HuRef	9	103,655,486 - 103,675,048 (+)	NCBI		HuRef
CHM1_1	9	134,314,643 - 134,334,187 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	143,498,005 - 143,517,537 (+)	NCBI		T2T-CHM13v2.0

Plpp7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	31,985,540 - 32,000,827 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	31,985,540 - 32,000,832 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	32,095,528 - 32,110,815 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	32,095,528 - 32,110,820 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	31,951,171 - 31,966,340 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	31,917,660 - 31,932,829 (+)	NCBI		MGSCv36	mm8
Celera	2	31,799,207 - 31,814,376 (+)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	22.02	NCBI

Plpp7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	35,782,215 - 35,796,577 (+)	NCBI		GRCr8
mRatBN7.2	3	15,384,461 - 15,398,820 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	15,384,492 - 15,398,883 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	18,453,991 - 18,468,246 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	27,038,981 - 27,053,233 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	25,289,724 - 25,304,159 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	11,114,551 - 11,130,427 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	11,114,551 - 11,130,425 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	16,467,145 - 16,481,235 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	11,209,598 - 11,223,892 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	11,105,969 - 11,120,261 (+)	NCBI
Celera	3	10,131,465 - 10,145,728 (+)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

Plpp7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	1,076,524 - 1,092,025 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	1,081,748 - 1,092,025 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLPP7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	8,048,162 - 8,073,856 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	8,050,504 - 8,076,205 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	102,411,095 - 102,431,146 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	131,054,886 - 131,074,449 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	131,055,406 - 131,073,474 (+)	Ensembl	panpan1.1		panPan2

PLPP7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	52,781,110 - 52,796,763 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	52,781,020 - 52,796,433 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	52,043,935 - 52,059,596 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	53,679,783 - 53,702,330 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	53,679,785 - 53,695,393 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	52,457,375 - 52,479,854 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	52,777,850 - 52,800,341 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	52,870,823 - 52,893,382 (-)	NCBI		UU_Cfam_GSD_1.0

Plpp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	198,338,299 - 198,353,061 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	18,106,809 - 18,121,794 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	18,106,836 - 18,121,586 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLPP7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	271,268,870 - 271,283,655 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	271,268,843 - 271,283,657 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	305,285,168 - 305,300,506 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Plpp7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	4,606,409 - 4,619,912 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	4,606,693 - 4,619,852 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008005904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037994231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000012927 ⟹ ENSCSAP00000010944

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	12	6,832,283 - 6,849,598 (-)	Ensembl

RefSeq Acc Id:

XM_008005904 ⟹ XP_008004095

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	12	6,832,015 - 6,850,313 (-)	NCBI
Vero_WHO_p1.0	NW_023666079	8,658,852 - 8,709,428 (+)	NCBI

Sequence:

show sequence

GGATTGTCATTTGATTGGACTGTGATGCGCTGAAGCTGAATTCAAGACTGATTTAAAAAAAGAC
CTGCCAGCTTAATGAATGCTGTCACAGAGGGAGGAGCTGGACCTGACCCCAGGGACCCAGGATG
ATGCTGTCAATGACGTCGTTCACTCTATCTGGTGCCCAAAGAGGCCTCGGCCCAAGCAACACCG
TCCAGTTTACAGAACCAGGTCCAAGCTGCCAGGCCGCTGGGGCAGGCAGGCCTGGCTTGCAGGG
GTCTGGACGGCTCAGAGGGAAGCTGGTAAAAACAAGCTGCGGCGGAGAAGGCAGGGAGGCAGCC
ACGGTGGCGGCTCTGGGGGCAGCTCTTGTCTTCGGGGAGAAGGCCCTTGGAACCGGGCTGGCGT
CGGCCTTTTTGGGGTGAGCGGGGTCACCATGCCAGCTTCCCAGAGCCGGGCCCGCGCCAGGGAC
CGCAACAACGTCCTCAACCGGGCTGAGTTCCTGTCCCTGAACCAGCCCCCCAAAGGGGGCCCGG
AGCCCCGCAGCTCCGGCAGAAAGGCCTCCGGCCCCTCGGCACAGCCCCCACCTGCTGGTGACGG
GGCCCGAGAGCGACGCCAGTCACAGCAGCTGCCAGAGGAGGACTGCATGCAGCTGAACCCCTCC
TTCAAGGGCATCGCCTTCAACTCCCTGCTGGCCATCGATATCTGTATGTCCAAGCGGCTGGGGG
TGTGTGCCGGCCGGGCGGCGTCCTGGGCCAGTGCTCGCTCCATGGTCAAACTCATCGGCATCAC
GGGCCACGGCATCCCCTGGATCGGAGGCACCATCCTCTGCCTGGTGAAGAGCAGCACACTGGCC
GGACAGGAGGTGCTCATGAATCTGCTCCTGGCCCTGCTCCTGGACATCATGACAGTGGCTGGCG
TGCAGAAGCTCATCAAGCGGCGTGGCCCGTACGAGACGAGCCCCAGCCTCCTGGACTACCTCAC
CATGGACGTCTACGCCTTCCCAGCCGGGCACGCCAGCCGCGCCGCCATGGTGTCCAAGTTCTTC
CTCAGCCACCTGGTGCTGGCGGTGCCCCTGCGTGTGCTGCTGGTGCTCTGGGCCCTCTGCGTGG
GCCTGTCCCGCGTGATGATTGGCCGCCACCACGTCACGGACGTCCTCTCTGGCTTCGTCATCGG
CTACCTCCAGTTCCGCCTGGTGGAGCTGGTCTGGATGCCCTCCAGCACCTGCCAGATGCTCATC
TCCGCCTGGTGAAGCGCCCGCTGGCCCACGCAAGGCTCTGGGGGCAGGGCTGGCCCTAGAGAAG
GGGCAGGGGATGGCAAGGTGGCAGGCGCGGGTTGAACAGAGCCACCAGGAGTTGGAGCGGCCAC
CCCCACCCCGTCTTCCCCTCCTGGTTGGAAGCCAGTGAACCCAGGCCGCCCCTTCCAGTGACAA
GCGTGTTTGGCAGTGCCAGGCCTCTTGCCCCTTTGCTTGGACTCCAAGTCTCCTCTCTAGGCGG
CCCGGACCCACCCGTGGGGACAGC

hide sequence

RefSeq Acc Id:

XM_037994231 ⟹ XP_037850159

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666079	8,659,139 - 8,709,428 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008004095	(Get FASTA)	NCBI Sequence Viewer
	XP_037850159	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000010944.1

RefSeq Acc Id:	XP_008004095 ⟸ XM_008005904
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_037850159 ⟸ XM_037994231
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RQQ5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000010944 ⟸ ENSCSAT00000012927

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000014839	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000012927.1	UniProtKB/TrEMBL
Gene3D-CATH	Phosphatidic acid phosphatase type 2/haloperoxidase	UniProtKB/TrEMBL
InterPro	P_Acid_Pase_2/haloperoxi_sf	UniProtKB/TrEMBL
	P_Acid_Pase_2/haloperoxidase	UniProtKB/TrEMBL
NCBI Gene	PLPP7	ENTREZGENE
PANTHER	INACTIVE PHOSPHOLIPID PHOSPHATASE 7	UniProtKB/TrEMBL
	SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE	UniProtKB/TrEMBL
Pfam	PAP2	UniProtKB/TrEMBL
SMART	acidPPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48317	UniProtKB/TrEMBL
UniProt	A0A0D9RQQ5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-12-08	LOC103239735	inactive phospholipid phosphatase 7	PLPP7	phospholipid phosphatase 7 (inactive)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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